Assessment of dose to vaginal mucosa for gynecologic template interstitial high-dose-rate brachytherapy using Monte Carlo simulation.
brachytherapy
dosimetry calculations
gynecologic cancers
interstitial radiotherapy
Journal
Journal of contemporary brachytherapy
ISSN: 1689-832X
Titre abrégé: J Contemp Brachytherapy
Pays: Poland
ID NLM: 101506276
Informations de publication
Date de publication:
Oct 2023
Oct 2023
Historique:
received:
01
06
2023
accepted:
19
09
2023
medline:
29
11
2023
pubmed:
29
11
2023
entrez:
29
11
2023
Statut:
ppublish
Résumé
This study investigated reliable vaginal mucosa dose-volume histogram (DVH) metrics in gynecologic template interstitial high-dose-rate brachytherapy (HDR-BT) for the purpose of standardized dose reporting. Gynecologic template (Syed/Neblett) interstitial HDR-BT patients treated from September 2016 to November 2022 at the study institute were included in the cohort. Each patient implant included a vaginal mucosa contour defined by a 5 mm expansion from vaginal cylinder, then another volume with clinical target volume subtracted. DVH metrics were investigated between D The patient cohort included 61 patients with clinical plans using conventional homogeneous dose calculation (TG43). Heterogeneous vs. water MC dose differences were between -1.1% and -1.4% for all metrics investigated. DVH metrics D For perineal template gynecologic HDR-BT procedures, the 2 cc volume is the smallest representative volume that reliably reports vaginal dose and at minimum should be reported to establish dose and outcome evaluation.
Identifiants
pubmed: 38026077
doi: 10.5114/jcb.2023.131781
pii: 51575
pmc: PMC10669914
doi:
Types de publication
Journal Article
Langues
eng
Pagination
317-324Informations de copyright
Copyright © 2023 Termedia.
Déclaration de conflit d'intérêts
Authors Roumeliotis and Meyer have ownership interest in Okolo Health, a brachytherapy company. The other authors report no conflict of interest. Supplementary material is available on the journal’s website.
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