Meropenem/Vaborbactam: β-Lactam/β-Lactamase Inhibitor Combination, the Future in Eradicating Multidrug Resistance.
Klebsiella pneumoniae carbapenemase (KPC)
carbapenem-resistant Enterobacterales (CRE)
meropenem
multidrug resistance
vaborbactam
β-lactam/β-lactamase inhibitor
Journal
Antibiotics (Basel, Switzerland)
ISSN: 2079-6382
Titre abrégé: Antibiotics (Basel)
Pays: Switzerland
ID NLM: 101637404
Informations de publication
Date de publication:
10 Nov 2023
10 Nov 2023
Historique:
received:
12
10
2023
revised:
04
11
2023
accepted:
08
11
2023
medline:
24
11
2023
pubmed:
24
11
2023
entrez:
24
11
2023
Statut:
epublish
Résumé
Due to the fact that there is a steadily increasing trend in the area of antimicrobial resistance in microorganisms, there is a need to look for new treatment alternatives. One of them is the search for new β-lactamase inhibitors and combining them with β-lactam antibiotics, with the aim of increasing the low-dose efficacy, as well as lowering the resistance potential of bacterial strains. This review presents the positive effect of meropenem in combination with a vaborbactam (MER-VAB). This latest antibiotic-inhibitor combination has found particular use in the treatment of infections with the etiology of carbapenem-resistant
Identifiants
pubmed: 37998814
pii: antibiotics12111612
doi: 10.3390/antibiotics12111612
pmc: PMC10668789
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
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