Cohort profile: the U-BIRTH study on peripartum depression and child development in Sweden.
Community child health
Depression & mood disorders
GYNAECOLOGY
PSYCHIATRY
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
10 11 2023
10 11 2023
Historique:
medline:
13
11
2023
pubmed:
11
11
2023
entrez:
10
11
2023
Statut:
epublish
Résumé
The current U-BIRTH cohort (Uppsala Birth Cohort) extends our previous cohort Biology, Affect, Stress, Imaging and Cognition (BASIC), assessing the development of children up to 11 years after birth. The U-BIRTH study aims to (1) assess the impact of exposure to peripartum mental illness on the children's development taking into account biological and environmental factors during intrauterine life and childhood; (2) identify early predictors of child neurodevelopmental and psychological problems using biophysiological, psychosocial and environmental variables available during pregnancy and early post partum. All mothers participating in the previous BASIC cohort are invited, and mother-child dyads recruited in the U-BIRTH study are consecutively invited to questionnaire assessments and biological sampling when the child is 18 months, 6 years and 11 years old. Data collection at 18 months (n=2882) has been completed. Consent for participation has been obtained from 1946 families of children having reached age 6 and from 698 families of children having reached age 11 years. Based on the complete data from pregnancy to 18 months post partum, peripartum mental health was significantly associated with the development of attentional control and gaze-following behaviours, which are critical to cognitive and social learning later in life. Moreover, infants of depressed mothers had an elevated risk of difficult temperament and behavioural problems compared with infants of non-depressed mothers. Analyses of biological samples showed that peripartum depression and anxiety were related to DNA methylation differences in infants. However, there were no methylation differences in relation to infants' behavioural problems at 18 months of age. Given that the data collection at 18 months is complete, analyses are now being undertaken. Currently, assessments for children reaching 6 and 11 years are ongoing.
Identifiants
pubmed: 37949626
pii: bmjopen-2023-072839
doi: 10.1136/bmjopen-2023-072839
pmc: PMC10649626
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e072839Informations de copyright
© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: None declared.
Références
J Affect Disord. 2016 Mar 15;193:391-404
pubmed: 26802316
Psychiatry Res. 2017 Sep;255:17-26
pubmed: 28511050
Adv Neurosci (Hindawi). 2014 May 1;2014:405094
pubmed: 25110757
Ann Epidemiol. 2021 Nov;63:1-6
pubmed: 34186179
Lancet. 2012 Feb 4;379(9814):445-52
pubmed: 22244654
J Affect Disord. 2020 Dec 1;277:109-114
pubmed: 32805586
J Speech Lang Hear Res. 2001 Apr;44(2):434-45
pubmed: 11324663
Int J Environ Res Public Health. 2021 Apr 28;18(9):
pubmed: 33924970
J Affect Disord. 2021 Aug 1;291:218-234
pubmed: 34049191
J Neurosci Res. 2020 Jul;98(7):1268-1282
pubmed: 30723972
Psychoneuroendocrinology. 2009 Oct;34(9):1329-37
pubmed: 19427131
JAMA Netw Open. 2020 Jun 1;3(6):e208783
pubmed: 32602910
R Soc Open Sci. 2020 Sep 16;7(9):201178
pubmed: 33047063
J Child Psychol Psychiatry. 2018 Feb;59(2):150-159
pubmed: 28925538
Horm Behav. 2017 Aug;94:106-113
pubmed: 28666923
Clin Epigenetics. 2021 Apr 12;13(1):78
pubmed: 33845866
PLoS One. 2016 Jan 25;11(1):e0144274
pubmed: 26807799
J Affect Disord. 2022 Nov 15;317:298-306
pubmed: 36031003
J Midwifery Womens Health. 2020 Jan;65(1):96-108
pubmed: 31970924
Child Psychiatry Hum Dev. 2012 Oct;43(5):683-714
pubmed: 22407278
J Am Coll Nutr. 2004 Dec;23(6 Suppl):588S-595S
pubmed: 15640511
Psychoneuroendocrinology. 2016 Jul;69:142-9
pubmed: 27088373
BMJ Open. 2019 Oct 22;9(10):e031514
pubmed: 31641004
Mol Neurobiol. 2023 Jul;60(7):3979-4003
pubmed: 37004608
J Autism Dev Disord. 2014 May;44(5):1064-76
pubmed: 24114582
Sci Rep. 2019 Apr 17;9(1):6213
pubmed: 30996270
Nature. 2007 May 24;447(7143):425-32
pubmed: 17522676
Transl Psychiatry. 2019 Aug 23;9(1):204
pubmed: 31444321
Best Pract Res Clin Obstet Gynaecol. 2014 Jan;28(1):3-12
pubmed: 24140480
Sci Rep. 2019 Oct 25;9(1):15328
pubmed: 31653981
J Clin Lab Anal. 2021 Aug;35(8):e23890
pubmed: 34263944
J Affect Disord. 2020 Aug 1;273:542-551
pubmed: 32560952
PLoS One. 2015 Aug 31;10(8):e0135471
pubmed: 26322643
Obstet Gynecol Clin North Am. 2021 Jun;48(2):325-337
pubmed: 33972069
Front Psychiatry. 2021 Jun 25;12:685656
pubmed: 34248718
BMC Pregnancy Childbirth. 2019 Jan 29;19(1):49
pubmed: 30696409
Psychoneuroendocrinology. 2019 May;103:296-305
pubmed: 30776573
J Child Psychol Psychiatry. 2003 Sep;44(6):793-809
pubmed: 12959489
Infant Behav Dev. 2006 Jul;29(3):386-401
pubmed: 17138293
J Clin Child Adolesc Psychol. 2005 Mar;34(1):93-104
pubmed: 15677284
J Affect Disord. 2017 Jan 01;207:141-147
pubmed: 27721188
Sci Rep. 2019 Feb 12;9(1):1863
pubmed: 30755659
Eur Child Adolesc Psychiatry. 2004;13 Suppl 3:3-13
pubmed: 15692877
J Affect Disord. 2017 Nov;222:177-184
pubmed: 28709025
Ann N Y Acad Sci. 2004 Dec;1032:234-6
pubmed: 15677418
Psychoneuroendocrinology. 2017 May;79:146-159
pubmed: 28285186
Lancet. 2014 Nov 15;384(9956):1800-19
pubmed: 25455250
Arch Womens Ment Health. 2016 Oct;19(5):711-20
pubmed: 27085795
Psychoneuroendocrinology. 2017 Jun;80:15-25
pubmed: 28292683
J Neurosci Res. 2020 Jul;98(7):1309-1321
pubmed: 30252150
Sci Rep. 2021 Dec 17;11(1):24190
pubmed: 34921204
J Exp Child Psychol. 2015 Feb;130:67-78
pubmed: 25462032
Reprod Sci. 2015 Oct;22(10):1281-8
pubmed: 25824011
Brain Behav Immun. 2020 Jul;87:901-909
pubmed: 32113908
Am J Obstet Gynecol. 2010 Jan;202(1):5-14
pubmed: 20096252
J Paediatr Child Health. 2019 Jan;55(1):87-94
pubmed: 30051946
Psychoneuroendocrinology. 2013 Dec;38(12):3150-4
pubmed: 24041544
Mol Psychiatry. 2014 May;19(5):560-7
pubmed: 23689534
J Affect Disord. 2017 Sep;219:86-92
pubmed: 28531848
Ups J Med Sci. 2020 Feb;125(1):30-36
pubmed: 31960733
JAMA Pediatr. 2020 Nov 1;174(11):1082-1092
pubmed: 32926075
Early Hum Dev. 2011 May;87(5):373-80
pubmed: 21420261
J Clin Child Adolesc Psychol. 2006 Jun;35(2):302-12
pubmed: 16597226
Obstet Gynecol. 2005 Nov;106(5 Pt 1):1071-83
pubmed: 16260528
Transl Psychiatry. 2022 May 5;12(1):186
pubmed: 35513368
JAMA Psychiatry. 2023 May 1;80(5):425-431
pubmed: 36884232
Health Policy. 1990 Dec;16(3):199-208
pubmed: 10109801
BMC Pregnancy Childbirth. 2019 Dec 5;19(1):479
pubmed: 31805950
Psychol Med. 2015 Jul;45(10):2023-30
pubmed: 25628053
Arch Womens Ment Health. 2005 Jun;8(2):77-87
pubmed: 15883651
BJOG. 2020 Oct;127(11):1382-1390
pubmed: 32339378
Arch Womens Ment Health. 2013 Jun;16(3):237-45
pubmed: 23462983
Depress Anxiety. 2016 Nov;33(11):1023-1030
pubmed: 27232288