Fluid shear stress triggers cholesterol biosynthesis and uptake in inner medullary collecting duct cells, independently of nephrocystin-1 and nephrocystin-4.
NPHP1
NPHP4
cholesterol
nephronophthisis
shear stress
Journal
Frontiers in molecular biosciences
ISSN: 2296-889X
Titre abrégé: Front Mol Biosci
Pays: Switzerland
ID NLM: 101653173
Informations de publication
Date de publication:
2023
2023
Historique:
received:
07
07
2023
accepted:
15
09
2023
medline:
2
11
2023
pubmed:
2
11
2023
entrez:
2
11
2023
Statut:
epublish
Résumé
Renal epithelial cells are subjected to fluid shear stress of urine flow. Several cellular structures act as mechanosensors-the primary cilium, microvilli and cell adhesion complexes-that directly relay signals to the cytoskeleton to regulate various processes including cell differentiation and renal cell functions. Nephronophthisis (NPH) is an autosomal recessive tubulointerstitial nephropathy leading to end-stage kidney failure before adulthood.
Identifiants
pubmed: 37916190
doi: 10.3389/fmolb.2023.1254691
pii: 1254691
pmc: PMC10616263
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1254691Informations de copyright
Copyright © 2023 Garfa Traoré, Roccio, Miceli, Ferri, Parisot, Cagnard, Lhomme, Dupont, Benmerah, Saunier and Delous.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Biol Cell. 2011 Mar;103(3):109-30
pubmed: 21275904
Cold Spring Harb Perspect Biol. 2017 Mar 1;9(3):
pubmed: 27793968
FASEB J. 2017 May;31(5):1796-1806
pubmed: 28100643
J Biol Chem. 2002 Aug 9;277(32):29028-35
pubmed: 12006559
Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115960119
pubmed: 35482924
Am J Physiol Renal Physiol. 2003 Nov;285(5):F998-F1012
pubmed: 12837680
Nat Genet. 2005 May;37(5):537-43
pubmed: 15852005
Biomed Pharmacother. 2018 Dec;108:1123-1134
pubmed: 30372813
Front Cell Dev Biol. 2021 May 13;9:653138
pubmed: 34055783
Curr Opin Pediatr. 2015 Apr;27(2):212-8
pubmed: 25575298
Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1398-F1405
pubmed: 30089029
Am J Physiol Cell Physiol. 2011 Aug;301(2):C451-60
pubmed: 21525434
Genome Biol. 2002 Jun 18;3(7):RESEARCH0034
pubmed: 12184808
Pediatr Transplant. 2008 Dec;12(8):878-82
pubmed: 19000067
Nat Rev Mol Cell Biol. 2008 Feb;9(2):125-38
pubmed: 18216769
Nat Cell Biol. 2020 Sep;22(9):1091-1102
pubmed: 32868900
Curr Pharm Biotechnol. 2012 Feb;13(2):303-18
pubmed: 21470123
Exp Cell Res. 2005 May 1;305(2):333-42
pubmed: 15817158
J Cell Physiol. 2018 Apr;233(4):3615-3628
pubmed: 29044509
Am J Physiol Renal Physiol. 2012 Sep;303(5):F632-8
pubmed: 22696602
Pediatr Nephrol. 2018 Oct;33(10):1701-1712
pubmed: 29974258
Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F815-F824
pubmed: 31364378
Nat Cell Biol. 2010 Nov;12(11):1115-22
pubmed: 20972424
Am J Physiol Cell Physiol. 2004 Apr;286(4):C831-9
pubmed: 14644772
Hum Mol Genet. 2021 Dec 27;31(2):232-243
pubmed: 34415307
Am J Physiol Renal Physiol. 2016 Aug 1;311(2):F450-8
pubmed: 27279484
J Am Soc Nephrol. 2009 Aug;20(8):1724-32
pubmed: 19478095
Hum Mol Genet. 2005 Mar 1;14(5):645-56
pubmed: 15661758
Clin J Am Soc Nephrol. 2017 Dec 7;12(12):1974-1983
pubmed: 29146700
Biochem Biophys Res Commun. 2020 Jan 8;521(2):290-295
pubmed: 31668373
Commun Biol. 2019 Jan 29;2:31
pubmed: 30729178
J Lipid Res. 2016 Mar;57(3):410-21
pubmed: 26685326
Front Cell Dev Biol. 2020 Dec 17;8:622822
pubmed: 33392209
J Am Soc Nephrol. 2009 Jan;20(1):23-35
pubmed: 19118152
Cell Mol Life Sci. 2012 Jan;69(1):165-73
pubmed: 21671118
Int J Mol Med. 2018 Oct;42(4):1809-1818
pubmed: 30015823
Nucleic Acids Res. 2018 Jul 2;46(W1):W242-W245
pubmed: 29762716
Nat Rev Mol Cell Biol. 2000 Oct;1(1):11-21
pubmed: 11413485
Am J Physiol Renal Physiol. 2012 Jun 1;302(11):F1409-17
pubmed: 22419690
Cell Calcium. 2013 May-Jun;53(5-6):327-37
pubmed: 23528238
Am J Physiol Renal Physiol. 2010 Nov;299(5):F1185-92
pubmed: 20719980
Science. 2011 Sep 30;333(6051):1888-91
pubmed: 21903779
Am J Hum Genet. 2011 Dec 9;89(6):713-30
pubmed: 22152675
Biochim Biophys Acta. 2011 Aug;1812(8):1007-22
pubmed: 21382489
Molecules. 2013 Apr 04;18(4):4002-17
pubmed: 23558541
Biochem Biophys Res Commun. 2011 Apr 22;407(4):813-7
pubmed: 21443862
Curr Opin Genet Dev. 2019 Jun;56:49-60
pubmed: 31419725
Hum Mol Genet. 2009 Dec 15;18(24):4711-23
pubmed: 19755384
Nat Rev Nephrol. 2020 Jun;16(6):337-351
pubmed: 32127698
Biomicrofluidics. 2020 Jul 02;14(4):044102
pubmed: 32665806
Biochem Biophys Res Commun. 2008 Jul 11;371(4):877-82
pubmed: 18477472
Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9784-9
pubmed: 11493697
Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11418-23
pubmed: 18685100
Hum Mol Genet. 2019 Mar 1;28(5):778-795
pubmed: 30388224
Genes Dev. 2002 May 1;16(9):1032-54
pubmed: 12000787
Am J Physiol Renal Physiol. 2015 Jun 1;308(11):F1229-37
pubmed: 25761882
Kidney Int. 2023 Aug;104(2):378-387
pubmed: 37230223
Hum Mol Genet. 2011 Jul 1;20(13):2611-27
pubmed: 21498478
Am J Physiol Renal Physiol. 2001 Oct;281(4):F751-62
pubmed: 11553522
Am J Physiol Heart Circ Physiol. 2015 Oct;309(7):H1178-85
pubmed: 26297225
Nat Cell Biol. 2016 Jun;18(6):657-67
pubmed: 27214279
Front Physiol. 2013 Oct 16;4:292
pubmed: 24137132
Nat Protoc. 2013 Nov;8(11):2281-2308
pubmed: 24157548
J Am Soc Nephrol. 2000 Feb;11(2):270-282
pubmed: 10665934
Exp Cell Res. 2000 Apr 10;256(1):168-78
pubmed: 10739664
Am J Physiol Renal Physiol. 2010 Dec;299(6):F1220-36
pubmed: 20810611