5-HT
5-HT(6) receptor
Antagonists
Non-sulfonyl compounds
Pyridine core
Serotonin receptor
Journal
Bioorganic & medicinal chemistry letters
ISSN: 1464-3405
Titre abrégé: Bioorg Med Chem Lett
Pays: England
ID NLM: 9107377
Informations de publication
Date de publication:
15 Nov 2023
15 Nov 2023
Historique:
received:
30
08
2023
revised:
01
10
2023
accepted:
02
10
2023
medline:
27
11
2023
pubmed:
9
10
2023
entrez:
8
10
2023
Statut:
ppublish
Résumé
In this study, we present the discovery and pharmacological characterization of a new series of 6-piperazinyl-7-azaindoles. These compounds demonstrate potent antagonism and selectivity against the 5-HT
Identifiants
pubmed: 37806499
pii: S0960-894X(23)00375-X
doi: 10.1016/j.bmcl.2023.129497
pii:
doi:
Substances chimiques
serotonin 6 receptor
0
Pyridines
0
VP1-001
0
Serotonin Antagonists
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
129497Informations de copyright
Copyright © 2023 Elsevier Ltd. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.