Quantum Sensing of Free Radicals in Primary Human Granulosa Cells with Nanoscale Resolution.


Journal

ACS central science
ISSN: 2374-7943
Titre abrégé: ACS Cent Sci
Pays: United States
ID NLM: 101660035

Informations de publication

Date de publication:
27 Sep 2023
Historique:
received: 20 06 2023
medline: 2 10 2023
pubmed: 2 10 2023
entrez: 2 10 2023
Statut: epublish

Résumé

Cumulus granulosa cells (cGCs) and mural granulosa cells (mGCs), although derived from the same precursors, are anatomically and functionally heterogeneous. They are critical for female fertility by supporting oocyte competence and follicular development. There are various techniques used to investigate the role of free radicals in mGCs and cCGs. Yet, temporospatial resolution remains a challenge. We used a quantum sensing approach to study free radical generation at nanoscale in cGCs and mGCs isolated from women undergoing oocyte retrieval during

Identifiants

pubmed: 37780363
doi: 10.1021/acscentsci.3c00747
pmc: PMC10540281
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1784-1798

Informations de copyright

© 2023 The Authors. Published by American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare the following competing financial interest(s): Unrelated to the current work, Prof. A. Hoek, is member of an advisory board on the development and application of a lifestyle app for patients with infertility, Ferring Pharmaceutical Company, The Netherlands.

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Auteurs

Nuan Lin (N)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.
Department of Obstetrics and Gynecology, The First Affiliated Hospital of Shantou University Medical College, 515041 Shantou, China.

Koen van Zomeren (K)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

Teelkien van Veen (T)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

Aldona Mzyk (A)

Department of Biomedical Engineering, Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.
Institute of Metallurgy and Materials Science, Polish Academy of Sciences, Reymonta 25, 30-059 Krakow, Poland.

Yue Zhang (Y)

Department of Biomedical Engineering, Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.

Xiaoling Zhou (X)

Center for Reproductive Medicine, Shantou University Medical College, Shantou 515041, China.

Torsten Plosch (T)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

Uwe J F Tietge (UJF)

Division of Clinical Chemistry, Department of Laboratory Medicine, Karolinska Institute, SE-141 52 Stockholm, Sweden.
Clinical Chemistry, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, SE-141 86 Stockholm, Sweden.

Astrid Cantineau (A)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

Annemieke Hoek (A)

Department of Obstetrics and Gynecology, University of Groningen, University Medical Center Groningen, 9713 GZ Groningen, The Netherlands.

Romana Schirhagl (R)

Department of Biomedical Engineering, Groningen University, University Medical Center Groningen, Antonius Deusinglaan 1, 9713 AW Groningen, The Netherlands.

Classifications MeSH