Effects of Different Hemoglobin Levels on Near-Infrared Spectroscopy-Derived Cerebral Oxygen Saturation in Elderly Patients Undergoing Noncardiac Surgery.

Near-infrared spectroscopy Red blood cell transfusion Regional cerebral oxygen saturation

Journal

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie
ISSN: 1660-3796
Titre abrégé: Transfus Med Hemother
Pays: Switzerland
ID NLM: 101176417

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 05 07 2022
accepted: 28 12 2022
medline: 28 9 2023
pubmed: 28 9 2023
entrez: 28 9 2023
Statut: epublish

Résumé

Near-infrared spectroscopy (NIRS) is a commonly used technique to evaluate tissue oxygenation and prevent harmful cerebral desaturation in the perioperative setting. The aims of the present study were to assess whether surgery-related anemia can be detected via NIRS of cerebral oxygen saturation and to investigate the effects of different perioperative transfusion strategies on cerebral oxygenation, potentially affecting transfusion decision-making. Data from the ongoing multicenter LIBERAL-Trial (liberal transfusion strategy to prevent mortality and anemia-associated ischemic events in elderly noncardiac surgical patients, LIBERAL) were used. In this single-center sub-study, regional cerebral oxygenation saturation (rSO rSO Cerebral oxygenation monitoring using NIRS provides noninvasive rapid and continuous information regarding perioperative alterations in Hb concentration without the utilization of patients' blood for blood sampling. Further investigations are required to demonstrate if cerebral rSO

Sections du résumé

Background UNASSIGNED
Near-infrared spectroscopy (NIRS) is a commonly used technique to evaluate tissue oxygenation and prevent harmful cerebral desaturation in the perioperative setting. The aims of the present study were to assess whether surgery-related anemia can be detected via NIRS of cerebral oxygen saturation and to investigate the effects of different perioperative transfusion strategies on cerebral oxygenation, potentially affecting transfusion decision-making.
Study Design and Methods UNASSIGNED
Data from the ongoing multicenter LIBERAL-Trial (liberal transfusion strategy to prevent mortality and anemia-associated ischemic events in elderly noncardiac surgical patients, LIBERAL) were used. In this single-center sub-study, regional cerebral oxygenation saturation (rSO
Results UNASSIGNED
rSO
Discussion UNASSIGNED
Cerebral oxygenation monitoring using NIRS provides noninvasive rapid and continuous information regarding perioperative alterations in Hb concentration without the utilization of patients' blood for blood sampling. Further investigations are required to demonstrate if cerebral rSO

Identifiants

pubmed: 37767283
doi: 10.1159/000528888
pii: tmh-0050-0270
pmc: PMC10521215
doi:

Types de publication

Journal Article

Langues

eng

Pagination

270-276

Informations de copyright

Copyright © 2023 by The Author(s). Published by S. Karger AG, Basel.

Déclaration de conflit d'intérêts

The authors have no conflicts of interest to declare.

Références

Br J Anaesth. 2011 Aug;107(2):209-17
pubmed: 21642644
J Clin Monit Comput. 2021 Apr;35(2):245-258
pubmed: 32815042
Transfusion. 2013 Jul;53(7):1459-67
pubmed: 23145971
J Pak Med Assoc. 2021 Feb;71(Suppl 2)(2):S10-S13
pubmed: 33785934
Adv Neonatal Care. 2011 Dec;11(6):382-8
pubmed: 22123468
J Perinatol. 2018 Aug;38(8):1022-1029
pubmed: 29740185
Transfus Med Rev. 2003 Apr;17(2):110-9
pubmed: 12733104
Anaesthesist. 2018 May;67(5):375-379
pubmed: 29644444
Trials. 2019 Feb 4;20(1):101
pubmed: 30717805
Transfus Med. 2007 Feb;17(1):1-15
pubmed: 17266700
Anesthesiology. 2011 Sep;115(3):548-54
pubmed: 21716091
JMIR Res Protoc. 2015 Dec 18;4(4):e137
pubmed: 26685289
Anesthesiology. 2015 Feb;122(2):241-75
pubmed: 25545654
Anesthesiology. 2000 Jun;92(6):1646-52
pubmed: 10839915
BMC Anesthesiol. 2021 Jun 1;21(1):165
pubmed: 34074238
Transfusion. 2020 Mar;60(3):466-472
pubmed: 31984520
Pediatr Clin North Am. 2017 Oct;64(5):991-1015
pubmed: 28941545
Anesth Analg. 2014 Dec;119(6):1381-92
pubmed: 25313967
Acta Neurochir (Wien). 2022 Apr;164(4):985-999
pubmed: 35220460
Transfusion. 2007 Apr;47(4):582-92
pubmed: 17381615
J Paediatr Child Health. 2019 Oct;55(10):1209-1213
pubmed: 30632233
PLoS One. 2020 Oct 30;15(10):e0240721
pubmed: 33125405
Am J Surg. 2011 May;201(5):592-8
pubmed: 21545905

Auteurs

Achilles Delis (A)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Derek Bautz (D)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Heidi Ehrentraut (H)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Karin Doll (K)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Thomas M Randau (TM)

Department of Orthopaedic and Trauma Surgery, University Hospital Bonn, Bonn, Germany.

Andreas C Strauss (AC)

Department of Orthopaedic and Trauma Surgery, University Hospital Bonn, Bonn, Germany.

Ivana Habicht (I)

Department of Orthopaedic and Trauma Surgery, University Hospital Bonn, Bonn, Germany.

Erdem Güresir (E)

Department of Neurosurgery, University Hospital Bonn, Bonn, Germany.

Holger Bogatsch (H)

Clinical Trial Center Leipzig, University Leipzig, Leipzig, Germany.

Peter Kranke (P)

Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.

Maria Wittmann (M)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Patrick Meybohm (P)

Department of Anaesthesiology, Intensive Care, Emergency and Pain Medicine, University Hospital Wuerzburg, Wuerzburg, Germany.

Markus Velten (M)

Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany.

Classifications MeSH