Glioma Response to IDH Inhibition: Real-World Experience.

Humans Brain Neoplasms / drug therapy Mutation Glioma / drug therapy Magnetic Resonance Imaging Isocitrate Dehydrogenase / genetics

Journal

Clinical cancer research : an official journal of the American Association for Cancer Research
ISSN: 1557-3265
Titre abrégé: Clin Cancer Res
Pays: United States
ID NLM: 9502500

Informations de publication

Date de publication:
01 Dec 2023
Historique:
received: 13 08 2023
revised: 28 08 2023
accepted: 07 09 2023
medline: 4 12 2023
pubmed: 22 9 2023
entrez: 22 9 2023
Statut: ppublish

Résumé

Treatment of IDH-mutated non-enhancing grade 2 and 3 diffuse gliomas with ivosidenib leads to reduction of tumor size when assessed via volumetric MRI. Isocitrate dehydrogenase inhibition has a therapeutic benefit in patients with these tumors. See related article by Kamson et al., p. 4863.

Identifiants

DOI: 10.1158/1078-0432.CCR-23-2164 PMID: 37738033
pubmed: 37738033
pii: 729226
doi: 10.1158/1078-0432.CCR-23-2164
doi:

Substances chimiques

Isocitrate Dehydrogenase EC 1.1.1.41

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4709-4710

Subventions

Organisme : National Cancer Institute (NCI)
ID : P50CA221747

Informations de copyright

©2023 American Association for Cancer Research.

Auteurs

Rimas V Lukas (RV)

Department of Neurology, Northwestern University, Chicago, Illinois.
Lou & Jean Malnati Brain Tumor Institute, Northwestern University, Chicago, Illinois.
ORCID: 0000-0002-9352-5396

Craig Horbinski (C)

Lou & Jean Malnati Brain Tumor Institute, Northwestern University, Chicago, Illinois.
Department of Neurological Surgery, Northwestern University, Chicago, Illinois.
Department of Pathology, Northwestern University, Chicago, Illinois.
ORCID: 0000-0001-8340-9992

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

Recherchemedicale.com › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Glioma Response to IDH Inhibition: Real-World...
Recherchemedicale.com › Maladies du système nerveux › Tumeurs du système nerveux › Tumeurs du système nerveux central › Tumeurs du cerveau › Glioma Response to IDH Inhibition: Real-World...
Recherchemedicale.com › Phénomènes génétiques › Variation génétique › Mutation › Glioma Response to IDH Inhibition: Real-World...
Recherchemedicale.com › Tumeurs › Tumeurs par type histologique › Tumeurs du tissu nerveux › Tumeurs neuroectodermiques › Tumeurs neuroépitheliales › Gliome › Glioma Response to IDH Inhibition: Real-World...
Recherchemedicale.com › Diagnostic › Techniques et procédures diagnostiques › Imagerie diagnostique › Tomographie › Imagerie par résonance magnétique › Glioma Response to IDH Inhibition: Real-World...
Recherchemedicale.com › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › NAD (+) and NADP (+) dependent Alcohol oxidoreductases › Isocitrate dehydrogenases › Glioma Response to IDH Inhibition: Real-World...