Cloning, purification and characterization of human dentine matrix protein 1(DMP1).
Cloning
Dentine matrix protein
Human
Purification
Journal
The Saudi dental journal
ISSN: 1013-9052
Titre abrégé: Saudi Dent J
Pays: Saudi Arabia
ID NLM: 9313603
Informations de publication
Date de publication:
Jul 2023
Jul 2023
Historique:
received:
16
12
2022
revised:
07
05
2023
accepted:
10
05
2023
medline:
31
7
2023
pubmed:
31
7
2023
entrez:
31
7
2023
Statut:
ppublish
Résumé
Human teeth are composed mainly of dentin, formed by the odontoblasts. Dentin matrix protein 1 (DMP1) is one of odontoblast differentiation's most important growth factors. Human DMP1 has yet to be completely identified or studied. This study aimed to clone and characterize human DMP1. The DMP1 gene sequence was prepared and cloned by transfection of human 293 cells. The recombinant DMP1 was purified and characterized. The results suggested its future use in dental tissue regeneration and tissue engineering.
Identifiants
pubmed: 37520603
doi: 10.1016/j.sdentj.2023.05.006
pii: S1013-9052(23)00087-1
pmc: PMC10373089
doi:
Types de publication
Journal Article
Langues
eng
Pagination
553-558Informations de copyright
© 2023 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
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