Anemia detection and quantification in contrast-enhanced CT scans on a novel photon-counting detector CT: A prospective proof-of-concept study.
Anemia
Computed tomography
Contrast media
Journal
European journal of radiology
ISSN: 1872-7727
Titre abrégé: Eur J Radiol
Pays: Ireland
ID NLM: 8106411
Informations de publication
Date de publication:
Sep 2023
Sep 2023
Historique:
received:
18
04
2023
revised:
31
05
2023
accepted:
07
07
2023
medline:
22
8
2023
pubmed:
25
7
2023
entrez:
24
7
2023
Statut:
ppublish
Résumé
To correlate CT values of the blood pool on VNC series with serum hemoglobin values for the detection of anemia in oncologic patients undergoing contrast-enhanced PCD-CT scans. This prospective study (NCT04989192) included consecutive oncologic patients undergoing contrast-enhanced CT on a novel PCD-CT system between 08/2021 and 01/2022. The interval between complete blood count (CBC) and CT scan acquisition had to be no more than seven days. CT-values of the blood pool were measured on 70 keV VMI series (CT-values(BP) A total of 329 patients (age 68 ± 12 years; 200 men) were included. CT-values(BP) The spectral information inherent in PCD-CT acquisitions allows the detection and quantification of anemia in contrast-enhanced CT acquisitions of oncologic patients with high diagnostic accuracy.
Identifiants
pubmed: 37487433
pii: S0720-048X(23)00281-4
doi: 10.1016/j.ejrad.2023.110967
pii:
doi:
Substances chimiques
Hemoglobins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
110967Informations de copyright
Copyright © 2023 Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Prof. Kroencke discloses receives institutional research support from Siemens Healthineers and Dr. Schwarz has received speaker honoraria from Siemens Healthineers. All other authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article.