Cancer risk in information technology workers: a UK Biobank study.


Journal

Occupational medicine (Oxford, England)
ISSN: 1471-8405
Titre abrégé: Occup Med (Lond)
Pays: England
ID NLM: 9205857

Informations de publication

Date de publication:
29 09 2023
Historique:
medline: 2 10 2023
pubmed: 21 7 2023
entrez: 21 7 2023
Statut: ppublish

Résumé

The information technology (IT) workforce has been growing more rapidly than others, with occupational health (OH) risks of sedentary behaviour, physical inactivity and poor diet, yet studies of their non-communicable disease risk, notably cancer, are lacking. To investigate cancer risk in IT workers compared to others in employment and the nine major Standard Occupational Classification (SOC) groups. We evaluated incident diagnosed cancers in the UK Biobank cohort through national cancer registry linkage. Cox proportional hazard regression models, with 15-year follow-up, were used to compare incident cancer risk among IT workers with all other employed participants and with the nine major SOC groups. Overall, 10 517 (4%) employed participants were IT workers. Adjusting for confounders, IT workers had a slightly lower cancer incidence compared to all other employed participants (Model 2: hazard ratio = 0.91, 95% confidence interval [CI] 0.83-1.01). Compared to the nine major SOC groups, they had a similar (Major Groups 2, 5 and 8) or lower (Major Groups 1, 3, 4, 6, 7 and 9) cancer incidence. Despite their occupational risks of sedentary behaviour, poor diet and physical inactivity, IT workers do not have an increased cancer incidence compared to all other employed participants and the nine major SOC groups. This study paves the way for large, longitudinal health outcome studies of this under-researched and rapidly growing occupational group.

Sections du résumé

BACKGROUND
The information technology (IT) workforce has been growing more rapidly than others, with occupational health (OH) risks of sedentary behaviour, physical inactivity and poor diet, yet studies of their non-communicable disease risk, notably cancer, are lacking.
AIMS
To investigate cancer risk in IT workers compared to others in employment and the nine major Standard Occupational Classification (SOC) groups.
METHODS
We evaluated incident diagnosed cancers in the UK Biobank cohort through national cancer registry linkage. Cox proportional hazard regression models, with 15-year follow-up, were used to compare incident cancer risk among IT workers with all other employed participants and with the nine major SOC groups.
RESULTS
Overall, 10 517 (4%) employed participants were IT workers. Adjusting for confounders, IT workers had a slightly lower cancer incidence compared to all other employed participants (Model 2: hazard ratio = 0.91, 95% confidence interval [CI] 0.83-1.01). Compared to the nine major SOC groups, they had a similar (Major Groups 2, 5 and 8) or lower (Major Groups 1, 3, 4, 6, 7 and 9) cancer incidence.
CONCLUSIONS
Despite their occupational risks of sedentary behaviour, poor diet and physical inactivity, IT workers do not have an increased cancer incidence compared to all other employed participants and the nine major SOC groups. This study paves the way for large, longitudinal health outcome studies of this under-researched and rapidly growing occupational group.

Identifiants

pubmed: 37477883
pii: 7227604
doi: 10.1093/occmed/kqad070
pmc: PMC10540665
mid: EMS187525
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

304-308

Subventions

Organisme : Medical Research Council
ID : MC_UU_00022/2
Pays : United Kingdom
Organisme : Chief Scientist Office
ID : SCAF/15/02
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_PC_13027
Pays : United Kingdom
Organisme : Chief Scientist Office
ID : SPHSU17
Pays : United Kingdom

Informations de copyright

© The Author(s) 2023. Published by Oxford University Press on behalf of the Society of Occupational Medicine.

Références

BMJ. 2020 Feb 12;368:m131
pubmed: 32051121
Int J Environ Res Public Health. 2021 Feb 22;18(4):
pubmed: 33671784
Occup Med (Lond). 2021 Apr 9;71(2):68-74
pubmed: 33515462
Nutrients. 2022 Mar 12;14(6):
pubmed: 35334858
Lancet Oncol. 2017 Aug;18(8):e457-e471
pubmed: 28759385
Int J Epidemiol. 2017 Dec 1;46(6):1797-1813
pubmed: 29025130
JNCI Cancer Spectr. 2019 May 22;3(2):pkz034
pubmed: 31360907

Auteurs

D Lalloo (D)

Healthy Working Lives Group, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.
MRC/CSO Social and Public Health Sciences Unit, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.

J Lewsey (J)

Health Economics and Health Technology Assessment, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.

S V Katikireddi (SV)

MRC/CSO Social and Public Health Sciences Unit, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.

E B Macdonald (EB)

Healthy Working Lives Group, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.

E Demou (E)

MRC/CSO Social and Public Health Sciences Unit, Clarice Pears Building, School of Health & Wellbeing, University of Glasgow, 90 Byres Road, Glasgow, G12 8TB, UK.

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