Accuracy of lung ultrasound in predicting extubation failure in neonates: A systematic review and meta-analysis.
diagnostic accuracy
extubation
lung ultrasound
meta-analysis
neonates
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
10 2023
10 2023
Historique:
revised:
06
06
2023
received:
29
04
2023
accepted:
03
07
2023
medline:
28
9
2023
pubmed:
11
7
2023
entrez:
11
7
2023
Statut:
ppublish
Résumé
To systematically review and meta-analyze the diagnostic accuracy of lung ultrasound score (LUS) in predicting extubation failure in neonates. MEDLINE, COCHRANE, EMBASE, CINAHL, and clinicaltrials.gov were searched up to 30 November 2022, for studies evaluating the diagnostic accuracy of LUS in predicting extubation outcome in mechanically ventilated neonates. Two investigators independently assessed study eligibility, extracted data, and assessed study quality using the Quality Assessment for Studies of Diagnostic Accuracy 2 tool. We conducted a meta-analysis of pooled diagnostic accuracy data using random-effect models. Data were reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We calculated pooled sensitivity and specificity, pooled diagnostic odds ratios with 95% confidence intervals (CI), and area under the curve (AUC). Eight observational studies involving 564 neonates were included, and the risk of bias was low in seven studies. The pooled sensitivity and specificity for LUS in predicting extubation failure in neonates were 0.82 (95% CI: 0.75-0.88) and 0.83 (95% CI: 0.78-0.86), respectively. The pooled diagnostic odds ratio was 21.24 (95% CI: 10.45-43.19), and the AUC for LUS predicting extubation failure was 0.87 (95% CI: 0.80-0.95). Heterogeneity among included studies was low, both graphically and by statistical criteria (I The predictive value of LUS in neonatal extubation failure may hold promise. However, given the current level of evidence and the methodological heterogeneity observed, there is a clear need for large-scale, well-designed prospective studies that establish standardized protocols for lung ultrasound performance and scoring. The protocol was registered in OSF (https://doi.org/10.17605/OSF.IO/ZXQUT).
Types de publication
Meta-Analysis
Systematic Review
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2846-2856Informations de copyright
© 2023 Wiley Periodicals LLC.
Références
Sant'Anna GM, Keszler M. Weaning infants from mechanical ventilation. Clin Perinatol. 2012;39(3):543-562.
Walsh MC, Morris BH, Wrage LA, et al. Extremely low birthweight neonates with protracted ventilation: mortality and 18-month neurodevelopmental outcomes. J Pediatr. 2005;146(6):798-804.
Jensen EA, DeMauro SB, Kornhauser M, Aghai ZH, Greenspan JS, Dysart KC. Effects of multiple ventilation courses and duration of mechanical ventilation on respiratory outcomes in extremely low-birth-weight infants. JAMA Pediatr. 2015;169(11):1011-1017.
Masry A, Nimeri NAMA, Koobar O, et al. Reintubation rates after extubation to different non-invasive ventilation modes in preterm infants. BMC Pediatr. 2021;21(1):281.
Sangsari R, Saeedi M, Maddah M, Mirnia K, Goldsmith JP. Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review. BMC Pulm Med. 2022;22(1):421.
Giaccone A, Jensen E, Davis P, Schmidt B. Definitions of extubation success in very premature infants: a systematic review. Arch Dis Childhood-Fetal Neonatal Edition. 2014;99(2):F124-F127.
Chawla S, Natarajan G, Shankaran S, et al. Markers of successful extubation in extremely preterm infants, and morbidity after failed extubation. J Pediatr. 2017;189:113-119.
Gupta D, Greenberg RG, Sharma A, et al. A predictive model for extubation readiness in extremely preterm infants. J Perinatol. 2019;39(12):1663-1669.
Shalish W, Kanbar L, Kovacs L, et al. Assessment of extubation readiness using spontaneous breathing trials in extremely preterm neonates. JAMA Pediatr. 2020;174(2):178-185.
He F, Wu D, Sun Y, Lin Y, Wen X, Cheng ASK. Predictors of extubation outcomes among extremely and very preterm infants: a retrospective cohort study. J Pediatr. 2022;98(6):648-654.
Shalish W, Latremouille S, Papenburg J, Sant'Anna GM. Predictors of extubation readiness in preterm infants: a systematic review and meta-analysis. Arch Dis Childhood-Fetal Neonatal Edition. 2019;104(1):F89-F97.
Kanbar LJ, Shalish W, Onu CC, et al. Automated prediction of extubation success in extremely preterm infants: the apex multicenter study. Pediatr Res. 2022;93(4):1041-1049.
Fernández LR, Hernández RG, Guerediaga IS, et al. Usefulness of lung ultrasound in the diagnosis and follow-up of respiratory diseases in neonates. Anales de Pediatría (English Edition).2022;96(3):252.e251-252.e213.
He L, Sun Y, Sheng W, Yao Q. Diagnostic performance of lung ultrasound for transient tachypnea of the newborn: a meta-analysis. PLoS One. 2021;16(3):e0248827.
Ma HR, Liu J, Yan WK. Accuracy and reliability of lung ultrasound to diagnose transient tachypnoea of the newborn: evidence from a meta-analysis and systematic review. Am J Perinatol. 2022;39(9):0973-0979.
Wang Y, Li N, Qu Y. Diagnostic accuracy of lung ultrasound for transient tachypnea: a meta-analysis. J Pediatr. 2022;98(4):329-337.
Ma H, Yan W, Liu J. Diagnostic value of lung ultrasound for neonatal respiratory distress syndrome: a meta-analysis and systematic review. Med Ultrasonog. 2020;22(3):325-333.
Wu J, Wang Y, Zhao A, Wang Z. Lung ultrasound for the diagnosis of neonatal respiratory distress syndrome: a meta-analysis. Ultrasound Q. 2020;36(2):102-110.
Pezza L, Alonso-Ojembarrena A, Elsayed Y, et al. Meta-analysis of lung ultrasound scores for early prediction of bronchopulmonary dysplasia. Ann Am Thorac Soc. 2022;19(4):659-667.
Razak A, Faden M. Neonatal lung ultrasonography to evaluate need for surfactant or mechanical ventilation: a systematic review and meta-analysis. Arch Dis Childhood-Fetal Neonatal Edition. 2020;105(2):164-171.
Capasso L, Pacella D, Migliaro F, et al. Can lung ultrasound score accurately predict surfactant replacement? A systematic review and meta-analysis of diagnostic test studies. Pediatr Pulmonol. 2023;58(5):1427-1437.
Eltomey MA, Shehata AH, Nassar MAE, Elmashad AEM. Can lung ultrasound assist in the decision of weaning mechanically ventilated neonates? Egyptian J Radiol Nuc Med. 2019;50(1):47.
El Amrousy D, Elgendy M, Eltomey M, Elmashad AE. Value of lung ultrasonography to predict weaning success in ventilated neonates. Pediatr Pulmonol. 2020;55(9):2452-2456.
Singhal M, Feinstein K, Schreiber M, Sriram S. Usefulness of lung ultrasound to determine extubation readiness in very low birth weight infants (abstract). Pediatric academic societies meeting, poster presentation.
Toma AI, Bogdan RD, Cuzino AI, et al. Use of lung ultrasound and and aeeg patterns to predict the need for mechanical ventilation and the readiness for extubation in neonates with respiratory distress. Rom Med J. 2021;68(5):105-112.
Awad HA, Khafagy SM, Ahmed NT, Shehata BM, Shabana AM. Lung ultrasonography as tool for follow up of ventilated neonates for prediction of weaning readiness. QJM: Int J Medi (abstract). 2021;114(supplment_1):hcab113.
Liang Z, Meng Q, You C, Wu B, Li X, Wu Q. Roles of lung ultrasound score in the extubation failure from mechanical ventilation among premature infants with neonatal respiratory distress syndrome. Front Pediatr. 2021;9:1368.
Jiang Q-X, Shi L-J, Shen L-Y, et al. Application value of a new lung ultrasound scoring method in neonatal respiratory distress syndrome treatment. Ultrasound Med Biol. 2022;48(2):275-282.
Mohsen N, Nasef N, Ghanem M, et al. Accuracy of lung and diaphragm ultrasound in predicting successful extubation in extremely preterm infants: a prospective observational study. Pediatr Pulmonol. 2023;58(2):530-539.
Llamas-Álvarez AM, Tenza-Lozano EM, Latour-Pérez J. Diaphragm and lung ultrasound to predict weaning outcome. Chest. 2017;152(6):1140-1150.
Page MJ, McKenzie JE, Bossuyt PM, et al. The prisma 2020 statement: an updated guideline for reporting systematic reviews. Int J Surg. 2021;88:105906.
McInnes MDF, Moher D, Thombs BD, et al. Preferred reporting items for a systematic review and meta-analysis of diagnostic test accuracy studies: the prisma-dta statement. JAMA. 2018;319(4):388-396.
Whiting PF, Weswood ME, Rutjes AW, Reitsma JB, Bossuyt PN, Kleijnen J. Evaluation of quadas, a tool for the quality assessment of diagnostic accuracy studies. BMC Med Res Methodol. 2006;6:9.
Reitsma JB, Glas AS, Rutjes AWS, Scholten RJPM, Bossuyt PM, Zwinderman AH. Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. JCE. 2005;58(10):982-990.
DerSimonian R, Laird N. Meta-analysis in clinical trials. Controlled Clin Trials. 1986;7(3):177-188.
Schünemann HJ, Mustafa RA, Brozek J, et al. Grade guidelines: 21 part 2. Test accuracy: inconsistency, imprecision, publication bias, and other domains for rating the certainty of evidence and presenting it in evidence profiles and summary of findings tables. JCE. 2020;122:142-152.
Biasucci DG, Loi B, Centorrino R, et al. Ultrasound-assessed lung aeration correlates with respiratory system compliance in adults and neonates with acute hypoxemic restrictive respiratory failure: an observational prospective study. Respir Res. 2022;23(1):360.
Brat R, Yousef N, Klifa R, Reynaud S, Shankar Aguilera S, De Luca D. Lung ultrasonography score to evaluate oxygenation and surfactant need in neonates treated with continuous positive airway pressure. JAMA Pediatr. 2015;169(8):e151797.
Zong H, Huang Z, Zhao J, et al. The value of lung ultrasound score in neonatology. Front Pediatr. 2022;10:791664.
Louis D, Belen K, Farooqui M, et al. Prone versus supine position for lung ultrasound in neonates with respiratory distress. Am J Perinatol. 2021;38(02):176-181.
Alonso-Ojembarrena A, Montero-Gato J, Gregorio-Hernández R, et al. Lung ultrasound scores progress differently in extreme and very preterm infants after birth: a multicentre prospective study. Neonatology. 2022;119(5):558-566.
Alonso-Ojembarrena A, Lubián-López SP. Lung ultrasound score as early predictor of bronchopulmonary dysplasia in very low birth weight infants. Pediatr Pulmonol. 2019;54(9):1404-1409.
Raimondi F, Yousef N, Migliaro F, Capasso L, De Luca D. Point-of-care lung ultrasound in neonatology: classification into descriptive and functional applications. Pediatr Res. 2021;90(3):524-531.
Wang J, Wei H, Chen H, et al. Application of ultrasonography in neonatal lung disease: an updated review. Front Pediatr. 2022;10:10.
Capasso L, Pacella D, Migliaro F, et al. Can lung ultrasound score accurately predict surfactant replacement? A systematic review and meta-analysis of diagnostic test studies. Pediatr Pulmonol. 2023;58:1427-1437.
Gunes AO, Karadag N, Cakir H, Toptan HH, Karatekin G. The associations between lung ultrasonography scores in the first day of life and clinical outcomes. J Ultrasound Med. 2022;41(2):417-425.