The Caries-Arrest Effectiveness of Silver Diamine Fluoride Treatment with Different Post-Treatment Instructions in Preschool Children: A Study Protocol for a Randomized Controlled Trial.
children
dental caries
early childhood caries
post-treatment instruction
randomized clinical trial
silver diamine fluoride
Journal
Dentistry journal
ISSN: 2304-6767
Titre abrégé: Dent J (Basel)
Pays: Switzerland
ID NLM: 101716125
Informations de publication
Date de publication:
05 Jun 2023
05 Jun 2023
Historique:
received:
27
03
2023
revised:
03
05
2023
accepted:
25
05
2023
medline:
27
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
In this 12-month randomized active-controlled clinical trial, we compare two post-treatment instructions for silver diamine fluoride (SDF) therapy in arresting dentine caries. The trial will include at least 254 kindergarten children with active dentine caries. The children will be randomized into two groups and receive a 38% SDF solution applied topically to their carious lesions. Children in Group A will rinse immediately, whereas those in Group B will refrain from rinsing, eating, and drinking for 30 min. One trained examiner will perform the dental examination at baseline and every six months. The primary outcome measurement will be the proportion of caries lesions that become arrested at the 12-month examination. Potential confounding factors and parents' satisfaction with SDF therapy at baseline and after 12 months will be collected using parental questionnaires. This trial will provide evidence-based information for clinical practitioners to give post-treatment instructions for SDF therapy. This study is registered at ClinicalTrial.gov (USA) (registration number: NCT05655286).
Identifiants
pubmed: 37366668
pii: dj11060145
doi: 10.3390/dj11060145
pmc: PMC10297061
pii:
doi:
Banques de données
ClinicalTrials.gov
['NCT05655286']
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : Government of Hong Kong
ID : Hong Kong Research Grant Council,17100019
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