Ethics Committees: Structure, Roles, and Issues.
Beneficence
Confidentiality
Ethics Committees, Research
Human Rights
Privacy
Research Subjects
Journal
Journal of Korean medical science
ISSN: 1598-6357
Titre abrégé: J Korean Med Sci
Pays: Korea (South)
ID NLM: 8703518
Informations de publication
Date de publication:
26 Jun 2023
26 Jun 2023
Historique:
received:
19
04
2023
accepted:
17
05
2023
medline:
28
6
2023
pubmed:
27
6
2023
entrez:
27
6
2023
Statut:
epublish
Résumé
An Ethics Committee (EC) is an independent body composed of members with expertise in both scientific and nonscientific arenas which functions to ensure the protection of human rights and the well-being of research subjects based on six basic principles of autonomy, justice, beneficence, nonmaleficence, confidentiality, and honesty. MEDLINE, Scopus, and Directory of Open Access Journals were searched for studies relevant to this topic. This review is focused on the types of research articles that need EC approval, the submission process, and exemptions. It further highlights the constitution of ECs, their duties, the review process, and the assessment of the risk-benefit of the proposed research including privacy issues. It's pertinent for academicians and researchers to abide by the rules and regulations put forth by ECs for upholding of human rights and protecting research subjects primarily, as well as avoiding other issues like retraction of publications. Despite various issues of cost, backlogs, lack of expertise, lesser representation of laypersons, need for multiple approvals for multisite projects, conflicts of interest, and monitoring of ongoing research for the continued safety of participants, the ECs form the central force in regulating research and participant safety. Data safety and monitoring boards complement the ECs for carrying out continuous monitoring for better protection of research subjects. The establishment of ECs has ensured safe study designs, the safety of human subjects along with the protection of researchers from before the initiation until the completion of a study.
Identifiants
pubmed: 37365729
pii: 38.e198
doi: 10.3346/jkms.2023.38.e198
pmc: PMC10293659
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e198Informations de copyright
© 2023 The Korean Academy of Medical Sciences.
Déclaration de conflit d'intérêts
The authors have no potential conflicts of interest to disclose.
Références
BMC Med Ethics. 2008 Mar 28;9:6
pubmed: 18373857
BMC Med Ethics. 2016 Feb 06;17:9
pubmed: 26852412
EMBO Rep. 2006 Sep;7(9):850-4
pubmed: 16953195
J Med Ethics. 2020 Aug;46(8):502-504
pubmed: 32461245
Ophthalmic Plast Reconstr Surg. 2013 Sep-Oct;29(5):335-40
pubmed: 24022348
Sci Rep. 2019 Sep 2;9(1):12637
pubmed: 31477792
BMJ Open. 2016 Nov 23;6(11):e012047
pubmed: 27881524
PLoS One. 2013;8(1):e54999
pubmed: 23383026
BMC Gastroenterol. 2022 Nov 21;22(1):477
pubmed: 36404304
BMC Anesthesiol. 2022 Jun 17;22(1):188
pubmed: 35715751
IRB. 2004 Mar-Apr;26(2):13-7
pubmed: 15069972
Indian J Med Ethics. 2019 Jul-Sept;4(3):178-183
pubmed: 31727613
Immunol Invest. 2023 Jan;52(1):134
pubmed: 33402009
Cureus. 2022 Mar 17;14(3):r55
pubmed: 35342661
J Surg Res. 2016 Aug;204(2):481-489
pubmed: 27565086
JAMA. 1970 Nov 16;214(7):1303-13
pubmed: 4320008
Milbank Q. 2011 Dec;89(4):599-627
pubmed: 22188349
J Cachexia Sarcopenia Muscle. 2019 Oct;10(5):1143-1145
pubmed: 31661195
Rev Infect Dis. 1986 Jan-Feb;8(1):157-62
pubmed: 3952423
Dev World Bioeth. 2017 Aug;17(2):84-89
pubmed: 27518590
JAMA. 2007 Sep 19;298(11):1277-8
pubmed: 17878419
Clin Invest Med. 2004 Dec;27(6):316-23
pubmed: 15675112
J Intern Med. 2011 Apr;269(4):396-402
pubmed: 21410788
Perspect Clin Res. 2012 Apr;3(2):50-6
pubmed: 22701820
J Korean Med Sci. 2021 Jan 18;36(3):e31
pubmed: 33463097
J Med Ethics. 2006 Mar;32(3):138-42
pubmed: 16507656
Eur J Clin Pharmacol. 2023 Apr;79(4):575-578
pubmed: 36884061
Acad Psychiatry. 2019 Jun;43(3):285-289
pubmed: 30706434
N Engl J Med. 1966 Jun 16;274(24):1354-60
pubmed: 5327352
BMC Med Ethics. 2013 Jun 05;14:23
pubmed: 23738971
J Med Virol. 2014 Nov;86(11):1998
pubmed: 25328930
BMC Pregnancy Childbirth. 2023 Feb 4;23(1):95
pubmed: 36739375
Pan Afr Med J. 2017 Nov 03;28:200
pubmed: 29610638
Seton Hall Law Rev. 2003;32(3):513-23
pubmed: 12741410
Muscle Nerve. 2003 Jul;28(1):27-39
pubmed: 12811770
BMC Med Ethics. 2020 May 13;21(1):37
pubmed: 32404098
Perspect Clin Res. 2017 Jan-Mar;8(1):22-30
pubmed: 28194334
Ther Innov Regul Sci. 2016 May;50(3):337-341
pubmed: 30227063
East Mediterr Health J. 2006;12 Suppl 1:S56-65
pubmed: 17037690
JAMA. 1996 Nov 27;276(20):1691
pubmed: 11644854
Bull Med Ethics. 2002 Oct;(182):17-23
pubmed: 14983848
J Med Ethics. 2008 Apr;34(4):301-2
pubmed: 18375685
N Engl J Med. 2005 Apr 28;352(17):1825-7
pubmed: 15858200
Mayo Clin Proc. 2019 Mar;94(3):515-525
pubmed: 30832791
BMJ. 2015 Oct 28;351:h5682
pubmed: 26514599
Indian J Med Ethics. 2009 Apr-Jun;6(2):78-84
pubmed: 19517650
J Am Acad Dermatol. 2008 Oct;59(4):718-9
pubmed: 18793941
J Ayub Med Coll Abbottabad. 2018 Oct-Dec;30(4):588-591
pubmed: 30632343
Health Res Policy Syst. 2016 Jan 19;14:5
pubmed: 26865158
Int J Technol Assess Health Care. 2007 Winter;23(1):17-23
pubmed: 17234012
Interact Cardiovasc Thorac Surg. 2022 Nov 8;35(6):
pubmed: 36458985
Pediatr Investig. 2018 May 11;2(1):46-51
pubmed: 32851230
Ann Intern Med. 2004 Aug 17;141(4):282-91
pubmed: 15313744
JAMA. 1997 Mar 19;277(11):925-6
pubmed: 9062334
CMAJ. 2004 Oct 26;171(9):1027-8
pubmed: 15505253
Gac Sanit. 2020 Sep - Oct;34(5):430-434
pubmed: 31530483
Springerplus. 2014 Sep 25;3:558
pubmed: 25392122
J Empir Res Hum Res Ethics. 2012 Feb;7(1):1-6
pubmed: 22378129
J Korean Med Sci. 2020 Nov 23;35(45):e398
pubmed: 33230988
Am J Health Syst Pharm. 2009 Jan 15;66(2):176-84
pubmed: 19139484
BMC Med Ethics. 2022 Nov 11;23(1):109
pubmed: 36368994
J Law Med Ethics. 2016 Sep;44(3):481-91
pubmed: 27587452
Rheumatol Int. 2011 Nov;31(11):1409-17
pubmed: 21800117
J Med Ethics. 2020 Nov 25;:
pubmed: 33239469
J Korean Med Sci. 2003 Feb;18(1):3-10
pubmed: 12589079