Pediatric Delirium: An Overlooked Diagnosis?


Journal

Pediatric neurology
ISSN: 1873-5150
Titre abrégé: Pediatr Neurol
Pays: United States
ID NLM: 8508183

Informations de publication

Date de publication:
Aug 2023
Historique:
received: 04 05 2022
revised: 03 02 2023
accepted: 02 04 2023
medline: 10 7 2023
pubmed: 5 6 2023
entrez: 4 6 2023
Statut: ppublish

Résumé

Delirium is well-recognized in adult inpatient care. However, it is often overlooked in children, being mistaken for pain, anxiety, or age-appropriate agitation. To assess the impact of a formal teaching session on the diagnostic rates and management of pediatric delirium (PD) in a tertiary care center, we conducted a retrospective chart review of all hospitalized children diagnosed with PD between August 2003 and August 2018 at the CHU Sainte-Justine (Montreal, Canada). Diagnostic incidence and management were compared before (2003 to 2014) and after (2015 to 2018) a formal teaching session provided to pediatric residents, staff pediatricians, and intensive care physicians in December 2014. The two cohorts displayed similar demographics, PD symptomatology, PD duration (median: 2 days), and hospital stay duration (median: 11.0 and 10.5 days). However, we saw a major increase in diagnosis frequency after 2014 (from 1.84 to 7.09 cases/year). This increased diagnostic rate was most striking in the pediatric intensive care unit setting. Although symptomatic treatment with antipsychotics and alpha-2 agonists was similar between the two cohorts, patients diagnosed after 2014 were more often weaned from offending medications (benzodiazepines, anesthetics, and anticholinergics). All patients recovered fully. Formal teaching on the symptoms and management of PD was associated with an increase in diagnostic rate and an improved management of PD in our institution. Larger studies are required to assess standardized screening tools that may further enhance diagnostic rates and improve care for children with PD.

Sections du résumé

BACKGROUND BACKGROUND
Delirium is well-recognized in adult inpatient care. However, it is often overlooked in children, being mistaken for pain, anxiety, or age-appropriate agitation.
METHODS METHODS
To assess the impact of a formal teaching session on the diagnostic rates and management of pediatric delirium (PD) in a tertiary care center, we conducted a retrospective chart review of all hospitalized children diagnosed with PD between August 2003 and August 2018 at the CHU Sainte-Justine (Montreal, Canada). Diagnostic incidence and management were compared before (2003 to 2014) and after (2015 to 2018) a formal teaching session provided to pediatric residents, staff pediatricians, and intensive care physicians in December 2014.
RESULTS RESULTS
The two cohorts displayed similar demographics, PD symptomatology, PD duration (median: 2 days), and hospital stay duration (median: 11.0 and 10.5 days). However, we saw a major increase in diagnosis frequency after 2014 (from 1.84 to 7.09 cases/year). This increased diagnostic rate was most striking in the pediatric intensive care unit setting. Although symptomatic treatment with antipsychotics and alpha-2 agonists was similar between the two cohorts, patients diagnosed after 2014 were more often weaned from offending medications (benzodiazepines, anesthetics, and anticholinergics). All patients recovered fully.
CONCLUSIONS CONCLUSIONS
Formal teaching on the symptoms and management of PD was associated with an increase in diagnostic rate and an improved management of PD in our institution. Larger studies are required to assess standardized screening tools that may further enhance diagnostic rates and improve care for children with PD.

Identifiants

pubmed: 37271057
pii: S0887-8994(23)00110-8
doi: 10.1016/j.pediatrneurol.2023.04.001
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

48-53

Informations de copyright

Copyright © 2023 Elsevier Inc. All rights reserved.

Auteurs

Audrey-Anne Lamoureux (AA)

CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.

Laurence Ducharme-Crevier (L)

Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.

Fanny Lacelle-Webster (F)

Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada; Department of Pediatrics, CHU Sherbrooke, University of Sherbrooke, Sherbrooke, Quebec, Canada.

Philippe Jouvet (P)

Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada.

Johanne Boivin (J)

Department of Psychiatry, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada.

Annie Lavoie (A)

Division of Pediatric Critical Care Medicine, Department of Pediatrics, CHU Sainte-Justine, Université de Montréal, Montréal, Québec, Canada; Department of Pharmacy, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada.

Elsa Rossignol (E)

Department of Pediatrics, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada; Department of Neurosciences, CHU Sainte-Justine, University of Montreal, Montreal, Quebec, Canada. Electronic address: elsa.rossignol@umontreal.ca.

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