Vaccination and Factors Related to the Clinical Outcome of COVID-19 in Healthcare Workers-A Romanian Front-Line Hospital's Experience.

COVID-19 clinical outcomes exposure healthcare workers individual risk vaccination

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
25 Apr 2023
Historique:
received: 27 03 2023
revised: 18 04 2023
accepted: 23 04 2023
medline: 27 5 2023
pubmed: 27 5 2023
entrez: 27 5 2023
Statut: epublish

Résumé

The study aims to describe the frequency of COVID-19 in healthcare workers (HCWs) in a designated hospital for COVID-19 treatment in Bucharest, Romania, and to explore COVID-19 vaccination and other factors associated with the clinical outcome. We actively surveyed all HCWs from 26 February 2020 to 31 December 2021. Cases were laboratory-confirmed with RT-PCR or rapid test antigen. Epidemiological, demographic, clinical outcomes, vaccination status, and co-morbidities data were collected. Data were analyzed using Microsoft Excel, SPSS, and MedCalc. A total of 490 cases of COVID-19 in HCWs were diagnosed. The comparison groups were related to the severity of the clinical outcome: the non-severe group (279, 64.65%) included mild and asymptomatic cases, and the potentially severe group included moderate and severe cases. Significant differences between groups were registered for high-risk departments (

Identifiants

pubmed: 37243002
pii: vaccines11050899
doi: 10.3390/vaccines11050899
pmc: PMC10222041
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Carmen-Daniela Chivu (CD)

Department of Epidemiology 1, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Emergency Clinical Hospital for Children "Grigore Alexandrescu", 011743 Bucharest, Romania.

Maria-Dorina Crăciun (MD)

Department of Epidemiology 1, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Emergency Clinical Hospital for Children "Grigore Alexandrescu", 011743 Bucharest, Romania.

Daniela Pițigoi (D)

Department of Epidemiology 1, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.

Victoria Aramă (V)

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.
Department of Infectious Diseases 1, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Monica Luminița Luminos (ML)

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.
Department of Infectious Diseases 3, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Gheorghiță Jugulete (G)

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.
Department of Infectious Diseases 3, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Cătălin Gabriel Apostolescu (CG)

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.
Department of Infectious Diseases 1, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Adrian Streinu Cercel (A)

National Institute for Infectious Diseases "Prof. Dr. Matei Balș", 021105 Bucharest, Romania.
Department of Infectious Diseases 1, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.

Classifications MeSH