Airway Stents from Now to the Future: A Narrative Review.

Airway stenosis Airway stent Bronchoscopy and interventional techniques

Journal

Respiration; international review of thoracic diseases
ISSN: 1423-0356
Titre abrégé: Respiration
Pays: Switzerland
ID NLM: 0137356

Informations de publication

Date de publication:
2023
Historique:
received: 19 07 2022
accepted: 20 03 2023
medline: 22 6 2023
pubmed: 26 5 2023
entrez: 26 5 2023
Statut: ppublish

Résumé

Airway stent insertion is important for patients with airway stenosis. Currently, the most widely used airway stents in clinical procedures are silicone and metallic stents, which offer patients effective treatment. However, these stents composed of permanent materials need to be removed, subjecting patients to invasive manipulation once more. As a result, there is a growing demand for biodegradable airway stents. Biodegradable materials for airway stents are now available in two types: biodegradable polymers and biodegradable alloys. Polymers that include poly (<sc>l</sc>-lactic acid), poly (D, <sc>l</sc>-lactide-co-glycolide), polycaprolactone, and polydioxanone are the ultimate metabolites which are generally carbon dioxide and water. Magnesium alloys are the most often utilized metal biodegradable materials for airway stents. The stent's mechanical properties and rate of degradation vary as a result of the different materials, cutting techniques, and structural configurations. We summarized the information above from recent studies on biodegradable airway stents conducted in both animals and humans. There is great potential for clinical applications for biodegradable airway stents. They avoid damage to the trachea during removal and reduce complications to some extent. However, several significant technical difficulties slow down the development of biodegradable airway stents. The efficacy and safety of different biodegradable airway stents still need to be investigated and proved.

Identifiants

pubmed: 37232032
pii: 000530421
doi: 10.1159/000530421
doi:

Substances chimiques

Polydioxanone 31621-87-1
Polymers 0
Alloys 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

439-448

Informations de copyright

© 2023 S. Karger AG, Basel.

Auteurs

Liangyuan Li (L)

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Laboratory of Pulmonary Immunology and Inflammation, Department of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.

Xinyuan Zhang (X)

Department of Applied Mechanics, College of Architecture and Environment, Sichuan Province Biomechanical Engineering Laboratory, Sichuan University, Chengdu, China.

Jingyu Shi (J)

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.

Yu Chen (Y)

Department of Applied Mechanics, College of Architecture and Environment, Sichuan Province Biomechanical Engineering Laboratory, Sichuan University, Chengdu, China.
Medical Big Data Center, Sichuan University, Chengdu, China.

Huajing Wan (H)

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Laboratory of Pulmonary Immunology and Inflammation, Department of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.

Felix J Herth (FJ)

Department of Pneumology and Critical Care Medicine, Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Centre Heidelberg (TLRC), Member of German Centre for Lung Research (DZL), Heidelberg, Germany.

Fengming Luo (F)

Department of Respiratory and Critical Care Medicine, West China Hospital, Sichuan University, Chengdu, China.
Laboratory of Pulmonary Immunology and Inflammation, Department of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.

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