Risk Factors and Role of Antibiotic Prophylaxis for Wound Infections after Percutaneous Endoscopic Gastrostomy.
antibiotic prophylaxis
head and neck cancer
percutaneous endoscopic gastrostomy (PEG)
radio-chemotherapy
wound infection
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
28 Apr 2023
28 Apr 2023
Historique:
received:
30
01
2023
revised:
29
03
2023
accepted:
05
04
2023
medline:
13
5
2023
pubmed:
13
5
2023
entrez:
13
5
2023
Statut:
epublish
Résumé
The incidence of wound infections after percutaneous endoscopic gastrostomy (PEG) varies widely in recent studies. The present study systematically investigates the underlying risk factors for the development of wound infections in a large cohort of patients over a long-term follow-up period. A retrospective cohort study of patients undergoing PEG insertion using either the pull or push technique was conducted and patients followed up for 3 years. Tube-related wound infections were identified, and pathogens regularly cultured from wound swabs. Adjusted analysis was performed via univariate and multivariate logistic regression analysis. 616 patients were included in this study. A total of 25% percent of patients developed wound infections upon PEG tube insertion and 6.5% showed recurrent infections. Nicotine abuse ( Wound infections after PEG placement are common and occasionally occur as recurrent infections. There is potential for improvement in everyday clinical practice, particularly regarding antibiotic prophylaxis in accordance with guidelines.
Sections du résumé
BACKGROUND AND STUDY AIM
OBJECTIVE
The incidence of wound infections after percutaneous endoscopic gastrostomy (PEG) varies widely in recent studies. The present study systematically investigates the underlying risk factors for the development of wound infections in a large cohort of patients over a long-term follow-up period.
PATIENTS AND METHODS
METHODS
A retrospective cohort study of patients undergoing PEG insertion using either the pull or push technique was conducted and patients followed up for 3 years. Tube-related wound infections were identified, and pathogens regularly cultured from wound swabs. Adjusted analysis was performed via univariate and multivariate logistic regression analysis.
RESULTS
RESULTS
616 patients were included in this study. A total of 25% percent of patients developed wound infections upon PEG tube insertion and 6.5% showed recurrent infections. Nicotine abuse (
CONCLUSIONS
CONCLUSIONS
Wound infections after PEG placement are common and occasionally occur as recurrent infections. There is potential for improvement in everyday clinical practice, particularly regarding antibiotic prophylaxis in accordance with guidelines.
Identifiants
pubmed: 37176616
pii: jcm12093175
doi: 10.3390/jcm12093175
pmc: PMC10179185
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
BMC Gastroenterol. 2022 Jul 28;22(1):361
pubmed: 35902805
Gastrointest Endosc. 2011 Jul;74(1):7-12
pubmed: 21704804
Dig Liver Dis. 2002 Dec;34(12):857-61
pubmed: 12643294
Z Gastroenterol. 2015 Dec;53(12):1496-530
pubmed: 26666284
Oral Oncol. 2022 Jul;130:105903
pubmed: 35569318
Arch Intern Med. 2004 Nov 8;164(20):2206-16
pubmed: 15534156
J Otolaryngol Head Neck Surg. 2013 Feb 28;42:20
pubmed: 23672761
JPEN J Parenter Enteral Nutr. 1994 May-Jun;18(3):264-7
pubmed: 8065003
Cancer Manag Res. 2020 Jan 08;12:127-136
pubmed: 32021429
BMC Gastroenterol. 2011 Mar 16;11:23
pubmed: 21410958
Ann Oncol. 2020 Nov;31(11):1462-1475
pubmed: 33239190
Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005571
pubmed: 17054265
Endoscopy. 2021 Feb;53(2):178-195
pubmed: 33348410
Support Care Cancer. 2011 Aug;19(8):1267-71
pubmed: 21553315
J Infect Prev. 2015 May;16(3):113-116
pubmed: 28989413
Gastrointest Endosc. 2008 Sep;68(3):580-4
pubmed: 18620346
Clin Otolaryngol. 2009 Apr;34(2):103-12
pubmed: 19413607
Laryngoscope Investig Otolaryngol. 2021 Sep 29;6(6):1325-1331
pubmed: 34938870
JPEN J Parenter Enteral Nutr. 2008 May-Jun;32(3):285-7
pubmed: 18443141
Cancer. 2020 Dec 1;126(23):5124-5136
pubmed: 32888342
JPEN J Parenter Enteral Nutr. 2009 Sep-Oct;33(5):472-500
pubmed: 19713551
J Pak Med Assoc. 1988 Jul;38(7):179-83
pubmed: 3149684
J Pediatr Gastroenterol Nutr. 2020 Jul;71(1):23-28
pubmed: 32205769
Front Oncol. 2021 Dec 02;11:784457
pubmed: 34926301
BMC Oral Health. 2012 Jul 20;12:22
pubmed: 22817766
JAMA. 2001 Oct 10;286(14):1754-8
pubmed: 11594901
Nutr Clin Pract. 2018 Feb;33(1):73-80
pubmed: 29323421