The landscape of exosomal non-coding RNAs in breast cancer drug resistance, focusing on underlying molecular mechanisms.
breast neoplasms
circular RNA
drug resistance
exosomes
long non-coding RNA
microRNAs
Journal
Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923
Informations de publication
Date de publication:
2023
2023
Historique:
received:
28
01
2023
accepted:
29
03
2023
medline:
8
5
2023
pubmed:
8
5
2023
entrez:
8
5
2023
Statut:
epublish
Résumé
Breast cancer (BC) is the most common malignancy among women worldwide. Like many other cancers, BC therapy is challenging and sometimes frustrating. In spite of the various therapeutic modalities applied to treat the cancer, drug resistance, also known as, chemoresistance, is very common in almost all BCs. Undesirably, a breast tumor might be resistant to different curative approaches (e.g., chemo- and immunotherapy) at the same period of time. Exosomes, as double membrane-bound extracellular vesicles 1) secreted from different cell species, can considerably transfer cell products and components through the bloodstream. In this context, non-coding RNAs (ncRNAs), including miRNAs, long ncRNAs (lncRNAs), and circular RNAs (circRNAs), are a chief group of exosomal constituents with amazing abilities to regulate the underlying pathogenic mechanisms of BC, such as cell proliferation, angiogenesis, invasion, metastasis, migration, and particularly drug resistance. Thereby, exosomal ncRNAs can be considered potential mediators of BC progression and drug resistance. Moreover, as the corresponding exosomal ncRNAs circulate in the bloodstream and are found in different body fluids, they can serve as foremost prognostic/diagnostic biomarkers. The current study aims to comprehensively review the most recent findings on BC-related molecular mechanisms and signaling pathways affected by exosomal miRNAs, lncRNAs, and circRNAs, with a focus on drug resistance. Also, the potential of the same exosomal ncRNAs in the diagnosis and prognosis of BC will be discussed in detail.
Identifiants
pubmed: 37153758
doi: 10.3389/fphar.2023.1152672
pii: 1152672
pmc: PMC10154547
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
1152672Informations de copyright
Copyright © 2023 Rezaee, Mohammadi, Keshavarzmotamed, Yahyazadeh, Vakili, Milasi, Veisi, Dehmordi, Asadi, Ghorbanhosseini, Rostami, Alimohammadi, Azadi, Moussavi, Asemi, Aminianfar, Mirzaei and Mafi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Mol Pharm. 2020 May 4;17(5):1723-1733
pubmed: 32233440
Oncol Res Treat. 2017;40(7-8):423-429
pubmed: 28683441
Trends Cell Biol. 2017 Mar;27(3):172-188
pubmed: 27979573
Am J Transl Res. 2015 Oct 15;7(10):2115-26
pubmed: 26692956
Cell Biosci. 2019 Feb 15;9:19
pubmed: 30815248
Mol Ther. 2019 Sep 4;27(9):1638-1652
pubmed: 31153828
J Stem Cell Res Ther. 2016 Oct;6(10):
pubmed: 27891292
Nature. 2012 Jul 19;487(7407):380-4
pubmed: 22801492
Trends Pharmacol Sci. 2012 Apr;33(4):207-14
pubmed: 22398146
J Cell Mol Med. 2021 Jan;25(1):15-26
pubmed: 33247543
Mol Cancer. 2015 Feb 10;14:36
pubmed: 25888956
Nat Rev Cancer. 2004 Dec;4(12):937-47
pubmed: 15573115
Cell Death Dis. 2020 Jan 22;11(1):43
pubmed: 31969559
RNA Biol. 2015;12(4):381-8
pubmed: 25746834
Cancer Manag Res. 2020 Sep 22;12:8733-8744
pubmed: 33061571
World J Surg Oncol. 2021 Feb 3;19(1):39
pubmed: 33536026
Mol Cancer. 2019 Mar 9;18(1):37
pubmed: 30849983
Nucleic Acids Res. 2019 Jan 8;47(D1):D155-D162
pubmed: 30423142
Trends Cancer. 2020 Apr;6(4):319-336
pubmed: 32209446
Gene. 2013 Nov 15;531(1):8-14
pubmed: 23994196
Stem Cell Res Ther. 2019 Aug 7;10(1):242
pubmed: 31391108
Cell Biochem Funct. 2022 Apr;40(3):232-247
pubmed: 35258097
J Cell Mol Med. 2020 Jul;24(13):7600-7608
pubmed: 32410348
Cell Death Dis. 2017 Jan 19;8(1):e2569
pubmed: 28102845
FEBS Lett. 2012 Oct 19;586(20):3761-5
pubmed: 23010597
J Biol Chem. 2008 Oct 31;283(44):29897-903
pubmed: 18708351
Dev Cell. 2011 Jul 19;21(1):77-91
pubmed: 21763610
Curr Biol. 2018 Apr 23;28(8):R435-R444
pubmed: 29689228
Nat Cell Biol. 2019 Apr;21(4):498-510
pubmed: 30936474
Cell. 2008 Sep 5;134(5):703-7
pubmed: 18775299
Int J Oncol. 2017 Sep;51(3):781-790
pubmed: 28766688
Cell Mol Life Sci. 2019 Nov;76(21):4203-4219
pubmed: 31300868
Biotechnol Appl Biochem. 2022 Aug;69(4):1633-1645
pubmed: 34342377
Mol Pharm. 2019 Aug 5;16(8):3333-3349
pubmed: 31241965
Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18697-702
pubmed: 25512540
Cell Mol Life Sci. 2016 Mar;73(6):1159-72
pubmed: 26686861
Lancet Oncol. 2008 Aug;9(8):730-56
pubmed: 18639491
BMC Cancer. 2011 Jun 15;11:248
pubmed: 21676217
Nature. 2014 Jan 16;505(7483):344-52
pubmed: 24429633
Mol Cell. 2017 Apr 6;66(1):22-37.e9
pubmed: 28344082
Curr Opin Pharmacol. 2018 Aug;41:59-65
pubmed: 29719270
Tumour Biol. 2014 Oct;35(10):9649-59
pubmed: 24969560
Proc Natl Acad Sci U S A. 2015 Feb 17;112(7):E616-24
pubmed: 25646478
Mol Biol Rep. 2022 Mar;49(3):2421-2432
pubmed: 34850336
Breast Cancer Res. 2012 Jan 19;14(1):202
pubmed: 22264257
BMC Cancer. 2013 Apr 02;13:174
pubmed: 23547709
Sci Rep. 2016 Dec 08;6:38750
pubmed: 27929118
J Cell Physiol. 2022 Apr;237(4):2095-2106
pubmed: 35128660
J Clin Oncol. 2003 Mar 15;21(6):968-75
pubmed: 12637459
Nat Rev Cardiol. 2019 Aug;16(8):503-514
pubmed: 30952956
Oncol Res. 2007;16(11):497-506
pubmed: 18306929
Cancer Chemother Pharmacol. 2020 Dec;86(6):761-772
pubmed: 33068176
Br J Cancer. 2011 Oct 25;105(9):1352-61
pubmed: 21970883
Bioinformation. 2016 Jun 15;12(3):135-139
pubmed: 28149048
Oncogene. 2013 Dec 12;32(50):5614-24
pubmed: 23955085
Lancet Oncol. 2015 Jan;16(1):67-75
pubmed: 25497694
J Extracell Vesicles. 2017 Mar 7;6(1):1286095
pubmed: 28326170
Hepatology. 2013 Dec;58(6):1964-76
pubmed: 23775631
Eur Rev Med Pharmacol Sci. 2016 Oct;20(20):4362-4368
pubmed: 27831634
Orphanet J Rare Dis. 2013 Jan 11;8:7
pubmed: 23311495
Cells Tissues Organs. 2018;205(5-6):279-292
pubmed: 30300884
Biomed Pharmacother. 2019 Jun;114:108800
pubmed: 30921705
Cancer Lett. 2009 Nov 28;285(2):116-26
pubmed: 19464788
Lancet. 1985 Aug 3;2(8449):282
pubmed: 2862460
Mol Cell Biochem. 2015 Jan;398(1-2):11-9
pubmed: 25223638
Noncoding RNA. 2018 Dec 12;4(4):
pubmed: 30545127
CNS Neurol Disord Drug Targets. 2022 Aug 29;:
pubmed: 36043720
Nat Med. 2013 Nov;19(11):1423-37
pubmed: 24202395
Curr Opin Cell Biol. 2008 Feb;20(1):4-11
pubmed: 18222686
Breast Cancer Res. 2004;6(5):R601-7
pubmed: 15318941
J Cell Biochem. 2019 Feb;120(2):1133-1140
pubmed: 29315763
Front Oncol. 2020 Sep 02;10:1569
pubmed: 32984016
Oncogene. 2019 Jun;38(26):5227-5238
pubmed: 30890754
Cell Death Dis. 2019 Jun 26;10(7):503
pubmed: 31243263
Cancer Chemother Pharmacol. 2005 Jan;55(1):21-32
pubmed: 15338192
Mol Ther Nucleic Acids. 2020 Mar 6;19:1434-1448
pubmed: 32160712
Cell. 2018 Feb 8;172(4):841-856.e16
pubmed: 29395328
Cancer Res. 2017 May 1;77(9):2242-2254
pubmed: 28249898
Oncogene. 1996 Sep 5;13(5):1103-9
pubmed: 8806701
Cancer Treat Rev. 2018 Jun;67:63-70
pubmed: 29763779
PLoS One. 2014 May 02;9(5):e96228
pubmed: 24788655
Nat Cell Biol. 2012 Jun 03;14(7):677-85
pubmed: 22660413
Cancers (Basel). 2020 Sep 15;12(9):
pubmed: 32942617
Int J Oncol. 2007 Aug;31(2):277-83
pubmed: 17611683
J Cell Biol. 2010 Sep 20;190(6):1079-91
pubmed: 20837771
J Cell Mol Med. 2018 Oct;22(10):4935-4947
pubmed: 30063126
Curr Med Chem. 2013;20(5):596-604
pubmed: 23278394
J Cell Physiol. 2016 Jan;231(1):25-30
pubmed: 26031493
Sci Rep. 2015 Mar 30;5:9301
pubmed: 25818003
Sci Rep. 2018 Aug 16;8(1):12252
pubmed: 30115973
Dis Markers. 2022 May 23;2022:5762686
pubmed: 35655918
Viruses. 2015 Jun 19;7(6):3204-25
pubmed: 26102580
Anticancer Drugs. 2022 Jan 1;33(1):e166-e177
pubmed: 34387598
FEBS Lett. 2015 Jun 4;589(13):1391-8
pubmed: 25937124
Cancer Res Treat. 2006 Dec;38(4):198-200
pubmed: 19771242
Cancer Cell. 2006 Jul;10(1):51-64
pubmed: 16843265
Thorac Cancer. 2020 Jul;11(7):1891-1903
pubmed: 32445273
Cell Commun Signal. 2022 Jan 28;20(1):13
pubmed: 35090496
Breast Cancer Res Treat. 2018 Aug;171(1):151-159
pubmed: 29736743
Cancer Res. 2009 Sep 1;69(17):6871-8
pubmed: 19671800
Nat Rev Cancer. 2006 Apr;6(4):259-69
pubmed: 16557279
Signal Transduct Target Ther. 2021 Nov 10;6(1):383
pubmed: 34753929
Sci Rep. 2018 Dec 19;8(1):17970
pubmed: 30568280
Int J Biol Macromol. 2023 Jan 15;225:1038-1048
pubmed: 36410538
CA Cancer J Clin. 2017 Nov;67(6):439-448
pubmed: 28972651
Mol Cancer. 2020 Dec 14;19(1):172
pubmed: 33317550
Trends Cell Biol. 2011 Jun;21(6):344-53
pubmed: 21601459
World J Clin Oncol. 2014 Aug 10;5(3):283-98
pubmed: 25114845
Nat Rev Cancer. 2011 Nov 24;11(12):849-64
pubmed: 22113163
Trends Cell Biol. 2020 Mar;30(3):226-240
pubmed: 31973951
Autophagy. 2017 Aug 3;13(8):1386-1403
pubmed: 28696138
Cancer Res. 2005 May 1;65(9):3509-12
pubmed: 15867338
PLoS One. 2014 Apr 16;9(4):e95240
pubmed: 24740415
Mol Cancer. 2018 Apr 20;17(1):82
pubmed: 29678180
J Biol Chem. 2013 Jun 21;288(25):18121-33
pubmed: 23649631
Oncotarget. 2015 Sep 8;6(26):22227-38
pubmed: 26087399
Trends Mol Med. 2014 Aug;20(8):460-9
pubmed: 25027972
Toxicol Sci. 2017 Jan;155(1):3-21
pubmed: 27864543
J Clin Oncol. 2006 Dec 20;24(36):5652-7
pubmed: 17116942
J Cell Sci. 2011 Oct 1;124(Pt 19):3344-55
pubmed: 21940797
PLoS Pathog. 2014 Oct 02;10(10):e1004424
pubmed: 25275643
Cancer Lett. 2018 Feb 1;414:107-115
pubmed: 29107112
Clin Breast Cancer. 2002 Oct;3 Suppl 2:S69-74
pubmed: 12435290
Arch Pathol Lab Med. 2010 Jul;134(7):e48-72
pubmed: 20586616
Biomark Med. 2018 Feb;12(2):177-188
pubmed: 29151358
Eur Rev Med Pharmacol Sci. 2015 Sep;19(18):3403-11
pubmed: 26439035
Int J Mol Sci. 2018 Apr 27;19(5):
pubmed: 29702599
Breast Cancer Res Treat. 2017 Feb;161(3):605-616
pubmed: 28000015
Tumour Biol. 2015 Mar;36(3):1395-401
pubmed: 25744731
Bioengineered. 2021 Dec;12(1):4032-4043
pubmed: 34288822
Pharmacol Ther. 2017 Jul;175:91-106
pubmed: 28216025
Cell Cycle. 2016 Dec;15(23):3278-3295
pubmed: 27753529
Prog Neurobiol. 2020 Mar;186:101746
pubmed: 31931031
Oncogene. 2005 Nov 14;24(50):7410-25
pubmed: 16288288
Adv Enzyme Regul. 2006;46:249-79
pubmed: 16854453
Cancer Res. 2016 Jun 1;76(11):3136-44
pubmed: 27009166
Clin Chim Acta. 2022 Dec 1;537:127-132
pubmed: 36330945
Nat Rev Cancer. 2016 Oct;16(10):635-49
pubmed: 27634447
Physiol Rev. 2016 Oct;96(4):1297-325
pubmed: 27535639
J Clin Endocrinol Metab. 2014 Sep;99(9):E1681-5
pubmed: 24937531
Cell Death Dis. 2018 Jan 11;9(1):14
pubmed: 29323124
Nat Rev Cancer. 2018 Jan;18(1):5-18
pubmed: 29170536
Oncol Lett. 2016 Jan;11(1):633-641
pubmed: 26870258
Front Endocrinol (Lausanne). 2018 Aug 03;9:402
pubmed: 30123182
Clin Cancer Res. 2018 May 15;24(10):2452-2463
pubmed: 29363524
Cancer Lett. 2009 Oct 8;283(2):168-75
pubmed: 19401262
Adv Sci (Weinh). 2020 Sep 24;7(21):2002518
pubmed: 33173749
BMC Cancer. 2018 Jan 6;18(1):41
pubmed: 29304770
Nat Commun. 2020 Jun 26;11(1):3256
pubmed: 32591500
Front Genet. 2019 May 22;10:496
pubmed: 31178900
RNA. 2003 Oct;9(10):1274-81
pubmed: 13130141
Transl Oncol. 2019 Oct;12(10):1305-1313
pubmed: 31336316
Sci Rep. 2018 Jan 16;8(1):829
pubmed: 29339789
Cancers (Basel). 2018 Aug 16;10(8):
pubmed: 30115848
Genes Genomics. 2022 May;44(5):539-550
pubmed: 35023068
Nat Rev Mol Cell Biol. 2018 Apr;19(4):213-228
pubmed: 29339798
J Natl Cancer Inst. 2003 Apr 2;95(7):526-32
pubmed: 12671020
Breast Cancer (Dove Med Press). 2021 Jan 06;13:1-7
pubmed: 33442288
Nature. 2012 Sep 6;489(7414):57-74
pubmed: 22955616
Mol Cancer. 2019 Jul 5;18(1):116
pubmed: 31277663
Ann N Y Acad Sci. 2007 Oct;1113:202-16
pubmed: 17513464
Medicine (Baltimore). 2017 Sep;96(36):e8000
pubmed: 28885360
Am J Cancer Res. 2021 May 15;11(5):1962-1981
pubmed: 34094664
Theranostics. 2020 Feb 10;10(8):3503-3517
pubmed: 32206104
Tumour Biol. 2016 Mar;37(3):3227-35
pubmed: 26432333
J Hematol Oncol. 2018 Apr 11;11(1):54
pubmed: 29642941
Theranostics. 2018 Mar 11;8(8):2251-2263
pubmed: 29721077
J Cell Biochem. 2020 Oct;121(10):4176-4187
pubmed: 31922280
Int J Mol Sci. 2016 Feb 06;17(2):170
pubmed: 26861301
Curr Drug Metab. 2019;20(10):804-814
pubmed: 31424364
Oncotarget. 2015 Oct 20;6(32):32774-89
pubmed: 26416415
Cancers (Basel). 2022 Jun 15;14(12):
pubmed: 35740618
PLoS One. 2013;8(2):e55820
pubmed: 23437065
Oncogene. 2020 Jan;39(5):953-974
pubmed: 31601996
Br J Cancer. 2014 Oct 14;111(8):1572-80
pubmed: 25117811
Nat Cell Biol. 2007 Jun;9(6):654-9
pubmed: 17486113
Int J Cancer. 2017 Jul 15;141(2):220-230
pubmed: 28240776
Biosci Rep. 2022 Jan 28;42(1):
pubmed: 34935899
Clin Cancer Res. 2005 Oct 15;11(20):7434-43
pubmed: 16243817
Cancers (Basel). 2022 Jan 09;14(2):
pubmed: 35053477
Front Cell Dev Biol. 2021 Apr 12;9:646864
pubmed: 33912560
J Cell Physiol. 2007 Jul;212(1):174-81
pubmed: 17299798
Sci Rep. 2017 Mar 27;7:45283
pubmed: 28345661
Oncogene. 2008 Jul 3;27(29):4086-95
pubmed: 18332865
Biochem Biophys Res Commun. 2018 Dec 2;506(4):819-825
pubmed: 30389133
Immunol Res. 2021 Dec;69(6):558-567
pubmed: 34559381
Int J Mol Sci. 2022 Jul 28;23(15):
pubmed: 35955480
Transl Oncol. 2021 Aug;14(8):101045
pubmed: 34023560
J Cell Physiol. 2020 Oct;235(10):6896-6904
pubmed: 31994191
Proc Natl Acad Sci U S A. 2009 May 19;106(20):8368-73
pubmed: 19416831
Oncotarget. 2016 Sep 13;7(37):59714-59726
pubmed: 27487127
Onco Targets Ther. 2020 Sep 24;13:9497-9511
pubmed: 33061434
Cancer Manag Res. 2019 Jun 12;11:5425-5435
pubmed: 31354350
Mol Biomed. 2021 Jun 30;2(1):20
pubmed: 35006452
Mol Cell Biochem. 2021 Nov;476(11):4081-4092
pubmed: 34273059
Cancer Cell Int. 2021 Jan 15;21(1):55
pubmed: 33451320
Sci Rep. 2016 Dec 08;6:38498
pubmed: 27929108
J Biomed Sci. 2019 Apr 25;26(1):29
pubmed: 31027496
Breast Cancer Res. 2008;10(6):R94
pubmed: 19014541
Cancer Res. 2016 Oct 1;76(19):5832-5844
pubmed: 27569215
Cell Physiol Biochem. 2017;44(5):1741-1748
pubmed: 29216623
Cancer Genet Cytogenet. 1999 Jun;111(2):161-5
pubmed: 10347556
Int J Mol Sci. 2017 Nov 03;18(11):
pubmed: 29099749
Circ Res. 2014 Jan 17;114(2):325-32
pubmed: 24436428
J Cell Biochem. 2004 Oct 1;93(2):242-50
pubmed: 15368352
J Clin Oncol. 2010 Mar 1;28(7):1145-53
pubmed: 20100965
J Neurosci Res. 2022 Sep;100(9):1775-1790
pubmed: 35642104
Clin Cancer Res. 2011 Nov 15;17(22):7105-15
pubmed: 21953503
EMBO J. 2011 Aug 31;30(17):3481-500
pubmed: 21878991
Mol Cancer Ther. 2001 Dec;1(2):85-94
pubmed: 12467226
Hum Mol Genet. 2010 Oct 15;19(R2):R152-61
pubmed: 20729297
Adv Exp Med Biol. 2016;937:3-17
pubmed: 27573892
Med Sci Monit. 2020 Aug 05;26:e922253
pubmed: 32756532
Int J Cancer. 2006 Jan 15;118(2):290-301
pubmed: 16080193
Cancer Res. 1997 Dec 15;57(24):5469-74
pubmed: 9407952
RNA. 2013 Feb;19(2):141-57
pubmed: 23249747
Onco Targets Ther. 2018 Aug 03;11:4525-4535
pubmed: 30122944
Anticancer Drugs. 2022 Jan 1;33(1):e700-e710
pubmed: 34845164
Gene. 2005 Sep 12;357(2):83-94
pubmed: 16111837
Lancet. 2017 Mar 18;389(10074):1134-1150
pubmed: 27865536
Clin Epigenetics. 2011 Aug;2(2):171-185
pubmed: 21949547
Breast Cancer Res Treat. 2020 Nov;184(2):287-300
pubmed: 32772271
J Transl Med. 2012 May 21;10:103
pubmed: 22613733
Cell. 2014 Mar 27;157(1):77-94
pubmed: 24679528
Noncoding RNA. 2015 Jun 03;1(1):53-68
pubmed: 29861415
Oncotarget. 2015 Apr 30;6(12):10253-66
pubmed: 25860935
J Clin Invest. 2013 Sep;123(9):3664-71
pubmed: 23999440
Cancers (Basel). 2020 Aug 12;12(8):
pubmed: 32806533
Breast Cancer Res Treat. 2008 May;109(2):325-35
pubmed: 17653856
Cancer Metastasis Rev. 2016 Dec;35(4):601-629
pubmed: 27858305
Clin Cancer Res. 2014 Jan 15;20(2):413-24
pubmed: 24173541
Med Sci Monit. 2019 Mar 26;25:2211-2220
pubmed: 30910994
Oncotarget. 2016 Apr 12;7(15):19601-9
pubmed: 26910922
Bioengineered. 2022 Mar;13(3):7197-7208
pubmed: 35263216
J Clin Oncol. 1987 Feb;5(2):172-7
pubmed: 3806165
Oncotarget. 2016 Dec 6;7(49):81452-81462
pubmed: 27845892
Breast Cancer Res Treat. 2014 Sep;147(2):423-31
pubmed: 25007959
Nat Rev Genet. 2019 Nov;20(11):675-691
pubmed: 31395983
Lancet Oncol. 2014 Dec;15(13):1469-1480
pubmed: 25456366
Biochemistry (Mosc). 2018 May;83(5):603-611
pubmed: 29738694
Front Genet. 2015 Jan 26;6:2
pubmed: 25674102
Rev Neurosci. 2019 Dec 18;31(1):77-87
pubmed: 31318699
Annu Rev Cell Dev Biol. 2014;30:255-89
pubmed: 25288114
Oncogene. 1992 Jun;7(6):1185-9
pubmed: 1594247
Cancer Lett. 2016 Jul 10;377(1):87-96
pubmed: 27130664
Science. 2017 Mar 24;355(6331):1324-1330
pubmed: 28336670
Oncol Lett. 2017 May;13(5):3100-3108
pubmed: 28521415
Biochim Biophys Acta. 2013 Jun;1833(6):1356-66
pubmed: 23485394
Curr Drug Targets. 2010 Sep;11(9):1074-88
pubmed: 20545611
Autophagy. 2019 Apr;15(4):599-612
pubmed: 30403914
Mol Cancer. 2021 Mar 1;20(1):43
pubmed: 33648498
World J Surg. 2022 Apr;46(4):836-844
pubmed: 35001140
Cancer Cell Int. 2021 Jul 19;21(1):384
pubmed: 34281530
Proc Natl Acad Sci U S A. 2016 May 3;113(18):E2526-35
pubmed: 27091996
Cancers (Basel). 2022 Mar 23;14(7):
pubmed: 35406386
Carcinogenesis. 2017 May 1;38(5):485-491
pubmed: 28449079
Annu Rev Cell Dev Biol. 2003;19:397-422
pubmed: 14570575
Endocr Relat Cancer. 2004 Dec;11(4):643-58
pubmed: 15613444
J Pathol. 2010 Jan;220(1):71-86
pubmed: 19768731
Cell Biochem Funct. 2021 Dec;39(8):955-969
pubmed: 34708430
Nat Commun. 2014 Jun 20;5:4121
pubmed: 24947672
EMBO J. 1996 Oct 1;15(19):5290-8
pubmed: 8895574
Gene. 2017 Jan 5;596:110-118
pubmed: 27746366
J Clin Endocrinol Metab. 2004 Mar;89(3):1102-7
pubmed: 15001594
Nat Biotechnol. 2014 May;32(5):453-61
pubmed: 24811520
Radiat Oncol. 2019 Apr 15;14(1):64
pubmed: 30987655
Oncotarget. 2017 Sep 21;8(54):91990-92003
pubmed: 29190892
Nat Rev Cancer. 2018 Jul;18(7):452-464
pubmed: 29643473
Drug Resist Updat. 2022 Jul;63:100851
pubmed: 35810716
Mol Cell Biol. 2008 Sep;28(18):5605-20
pubmed: 18625725
Nat Commun. 2019 Sep 26;10(1):4375
pubmed: 31558756
Pathol Res Pract. 2021 Nov;227:153618
pubmed: 34649056
Cell Death Dis. 2014 Jan 23;5:e1008
pubmed: 24457952
Am J Transl Res. 2020 Jun 15;12(6):2585-2599
pubmed: 32655792
Cell Mol Biol Lett. 2022 Aug 3;27(1):65
pubmed: 35922753
BMC Cancer. 2019 Mar 8;19(1):211
pubmed: 30849956
Curr Opin Cell Biol. 2011 Aug;23(4):452-7
pubmed: 21570275
Am J Transl Res. 2017 Jun 15;9(6):2956-2965
pubmed: 28670383
Drug Discov Ther. 2020 Sep 8;14(4):197-203
pubmed: 32863323
Sci Adv. 2016 May 27;2(5):e1600200
pubmed: 27386546
Front Pharmacol. 2020 Dec 09;11:592912
pubmed: 33362547
Cancers (Basel). 2021 Jul 22;13(15):
pubmed: 34359591
Proc Natl Acad Sci U S A. 1976 Nov;73(11):3852-6
pubmed: 1069269
Drug Dev Res. 2022 Feb;83(1):75-87
pubmed: 34227151
Cell Prolif. 2020 Jun;53(6):e12828
pubmed: 32391938
Semin Cell Dev Biol. 2015 Apr;40:41-51
pubmed: 25721812
Traffic. 2011 Dec;12(12):1659-68
pubmed: 21645191
Traffic. 2009 Jul;10(7):925-37
pubmed: 19490536
Front Oncol. 2021 Jul 06;11:639961
pubmed: 34295807