Granular cell tumor of the neurohypophysis presenting as a third ventricle mass.
granular cell tumor
pituicytoma
posterior pituitary
third ventricle
Journal
Neuropathology : official journal of the Japanese Society of Neuropathology
ISSN: 1440-1789
Titre abrégé: Neuropathology
Pays: Australia
ID NLM: 9606526
Informations de publication
Date de publication:
Dec 2023
Dec 2023
Historique:
revised:
11
04
2023
received:
30
01
2023
accepted:
14
04
2023
medline:
5
12
2023
pubmed:
6
5
2023
entrez:
6
5
2023
Statut:
ppublish
Résumé
Granular cell tumors of the neurohypophysis (GCT) are rare benign neoplasms belonging, along with pituicytoma and spindle cell oncocytoma, to the family of TTF1-positive low-grade neoplasms of the posterior pituitary gland. GCT usually present as a solid sellar mass, slowly growing and causing compressive symptoms over time, occasionally with suprasellar extension. They comprise polygonal monomorphous cells with abundant granular cytoplasm, which is ultrastructurally filled with lysosomes. Here we report the case of a GCT presenting as a third ventricle mass, radiologically mimicking chordoid glioma, with aberrant expression of GFAP and Annexin-A, which lends itself as an example of an integrated diagnostic approach to sellar/suprasellar and third ventricle masses.
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Pagination
472-478Informations de copyright
© 2023 Japanese Society of Neuropathology.
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