Long term association of hip fractures by questions of physical health in a cohort of men and women.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2023
Historique:
received: 08 07 2022
accepted: 11 03 2023
medline: 31 3 2023
entrez: 29 3 2023
pubmed: 30 3 2023
Statut: epublish

Résumé

We do not know if fracture predicting factors are constant throughout life, if they can be assessed earlier in life, and for how long. The aim was to study the association between questions about health status and mobility and fragility fractures in a cohort during a 35-year follow-up. A cohort of 16,536 men and women in two age groups, 26-45 and 46-65 years old, who answered five questions of their physical health status in postal surveys in 1969-1970. We obtained data on hip fractures from 1970 to the end of 2016. We found most significant results when restricting the follow-up to age 60-85 years, 35 for the younger age group and 20 years for the older. Men of both age groups considered "at risk" according to their answers had a 2.69 (CI 1.85-3.90)- 3.30 (CI 1.51-7.23) increased risk of having a hip fracture during a follow-up. Women in the younger age group had a 2.69 (CI 1.85-3.90) increased risk, but there was no elevated risk for women in the older age group. This study shows that questions/index of physical health status may be associated with hip fractures that occur many years later in life, and that there is a time span when the predictive value of the questions can be used, before other, age-related, factors dominate. Our interpretation of the results is that we are studying the most vulnerable, who have hip fractures relatively early in life, and that hip fractures are so common among older women that the questions in the survey lose their predictive value.

Identifiants

pubmed: 36989334
doi: 10.1371/journal.pone.0283564
pii: PONE-D-22-17362
pmc: PMC10058117
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0283564

Informations de copyright

Copyright: © 2023 Elleby et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Charlotta Elleby (C)

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Academic Centre for Geriatric Dentistry, Stockholm, Sweden.
Public Dental Services, Folktandvården, Stockholm, Sweden.

Pia Skott (P)

Academic Centre for Geriatric Dentistry, Stockholm, Sweden.
Public Dental Services, Folktandvården, Stockholm, Sweden.
Department of Dental Medicine, Karolinska Institutet, Huddinge, Sweden.

Sven-Erik Johansson (SE)

Center for Primary Health Care Research, Department of Clinical Sciences, Malmö, Lund University, Lund, Sweden.

Sven Nyrén (S)

Department of Molecular Medicine and Surgery, Karolinska Institutet, Solna, Sweden.

Holger Theobald (H)

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Academic Primary Care Health Centre, Region Stockholm, Stockholm, Sweden.

Helena Salminen (H)

Division of Family Medicine and Primary Care, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden.
Academic Primary Care Health Centre, Region Stockholm, Stockholm, Sweden.

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