Essential data dimensions for prospective international data collection in older age bipolar disorder (OABD): Recommendations from the GAGE-BD group.


Journal

Bipolar disorders
ISSN: 1399-5618
Titre abrégé: Bipolar Disord
Pays: Denmark
ID NLM: 100883596

Informations de publication

Date de publication:
Nov 2023
Historique:
medline: 24 11 2023
pubmed: 28 2 2023
entrez: 27 2 2023
Statut: ppublish

Résumé

By 2030, over 50% of individuals living with bipolar disorder (BD) are expected to be aged ≥50 years. However, older age bipolar disorder (OABD) remains understudied. There are limited large-scale prospectively collected data organized in key dimensions capable of addressing several fundamental questions about BD affecting this subgroup of patients. We developed initial recommendations for the essential dimensions for OABD data collection, based on (1) a systematic review of measures used in OABD studies, (2) a Delphi consensus of international OABD experts, (3) experience with harmonizing OABD data in the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD, n ≥ 4500 participants), and (4) critical feedback from 34 global experts in geriatric mental health. We identified 15 key dimensions and variables within each that are relevant for the investigation of OABD: (1) demographics, (2) core symptoms of depression and (3) mania, (4) cognition screening and subjective cognitive function, (5) elements for BD diagnosis, (6) descriptors of course of illness, (7) treatment, (8) suicidality, (9) current medication, (10) psychiatric comorbidity, (11) psychotic symptoms, (12) general medical comorbidities, (13) functioning, (14) family history, and (15) other. We also recommend particular instruments for capturing some of the dimensions and variables. The essential data dimensions we present should be of use to guide future international data collection in OABD and clinical practice. In the longer term, we aim to establish a prospective consortium using this core set of dimensions and associated variables to answer research questions relevant to OABD.

Sections du résumé

BACKGROUND BACKGROUND
By 2030, over 50% of individuals living with bipolar disorder (BD) are expected to be aged ≥50 years. However, older age bipolar disorder (OABD) remains understudied. There are limited large-scale prospectively collected data organized in key dimensions capable of addressing several fundamental questions about BD affecting this subgroup of patients.
METHODS METHODS
We developed initial recommendations for the essential dimensions for OABD data collection, based on (1) a systematic review of measures used in OABD studies, (2) a Delphi consensus of international OABD experts, (3) experience with harmonizing OABD data in the Global Aging & Geriatric Experiments in Bipolar Disorder Database (GAGE-BD, n ≥ 4500 participants), and (4) critical feedback from 34 global experts in geriatric mental health.
RESULTS RESULTS
We identified 15 key dimensions and variables within each that are relevant for the investigation of OABD: (1) demographics, (2) core symptoms of depression and (3) mania, (4) cognition screening and subjective cognitive function, (5) elements for BD diagnosis, (6) descriptors of course of illness, (7) treatment, (8) suicidality, (9) current medication, (10) psychiatric comorbidity, (11) psychotic symptoms, (12) general medical comorbidities, (13) functioning, (14) family history, and (15) other. We also recommend particular instruments for capturing some of the dimensions and variables.
CONCLUSION CONCLUSIONS
The essential data dimensions we present should be of use to guide future international data collection in OABD and clinical practice. In the longer term, we aim to establish a prospective consortium using this core set of dimensions and associated variables to answer research questions relevant to OABD.

Identifiants

pubmed: 36843436
doi: 10.1111/bdi.13312
doi:

Types de publication

Practice Guideline Systematic Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

554-563

Subventions

Organisme : International Society for Bipolar Disorder (ISBD) Bowden Massey Strategic Research Initiative
ID : www.isbd.org

Informations de copyright

© 2023 John Wiley & Sons Ltd. This article has been contributed to by U.S. Government employees and their work is in the public domain in the USA.

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Auteurs

Paola Lavin (P)

Department of Geriatric Psychiatry, Department of Psychiatry, Jewish General Hospital/Lady Davis Institute, McGill University, Montreal, Quebec, Canada.

Soham Rej (S)

Department of Geriatric Psychiatry, Department of Psychiatry, Jewish General Hospital/Lady Davis Institute, McGill University, Montreal, Quebec, Canada.

Andrew T Olagunju (AT)

Department of Psychiatry and Behavioral Neurosciences, McMaster University/St Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada.

Antonio L Teixeira (AL)

Department of Psychiatry and Behavioral Sciences, University of Texas/McGovern Medical School, Houston, Texas, USA.

Annemieke Dols (A)

Department of Old Age Psychiatry, GGZ inGeest, Amsterdam, The Netherlands.
Amsterdam UMC, Vrije Universiteit, Psychiatry, Amsterdam Public Health Research Institute, Amsterdam Neuroscience, Amsterdam, The Netherlands.

Martin Alda (M)

Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.

Osvaldo P Almeida (OP)

Medical School, University of Western Australia, Perth, Western Australia, Australia.

Kursat Altinbas (K)

Selçuk University Medical Faculty, Department of Psychiatry, Mazhar Osman Mood Clinic, Konya, Turkey.

Vicent Balanzá-Martínez (V)

Teaching Unit of Psychiatry and Psychological Medicine, Department of Medicine, University of Valencia, CIBERSAM, Valencia, Spain.

Izabela G Barbosa (IG)

Laboratório Interdisciplinar de Investigação Médica da Faculdad de Medicina, Universidad Federal de Minas Gerais, Belo Horizonte, Brazil.

Hilary P Blumberg (HP)

Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.

Farren Briggs (F)

Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Cynthia Calkin (C)

Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.

Kristin Cassidy (K)

Department of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Brent P Forester (BP)

Division of Geriatric Psychiatry, McLean Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Orestes V Forlenza (OV)

Laboratory of Neuroscience (LIM-27), Department and Institute of Psychiatry, HCFMUSP, Faculdad de Medicina da Universidad de São Paulo, São Paulo, Brazil.

Tomas Hajek (T)

Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada.
National Institute of Mental Health, Klecany, Czech Republic.

Barthomeus C M Haarman (BCM)

Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

Esther Jimenez (E)

Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.

Beny Lafer (B)

Department of Psychiatry, University of Sao Paulo, São Paulo, Brazil.

Benoit Mulsant (B)

Department of Psychiatry, University of Toronto, Center for Addiction and Mental Health, Toronto, Ontario, Canada.

Stephen O Oluwaniyi (SO)

Federal Neuro-psychiatric Hospital Yaba, Lagos, Nigeria.

Regan Patrick (R)

Division of Geriatric Psychiatry, McLean Hospital, Belmont, Massachusetts, USA.

Joaquim Radua (J)

Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.
Department of Clinical Neuroscience, Centre for Psychiatric Research and Education, Karolinska Institutet, Solna, Sweden.
Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, UK.

Sigfried Schouws (S)

Department of Old Age Psychiatry, GGZ inGeest, Amsterdam, The Netherlands.
Amsterdam UMC, Vrije Universiteit, Psychiatry, Amsterdam Public Health Research Institute, Amsterdam Neuroscience, Amsterdam, The Netherlands.

Harmehr Sekhon (H)

Department of Geriatric Psychiatry, Department of Psychiatry, Jewish General Hospital/Lady Davis Institute, McGill University, Montreal, Quebec, Canada.
Division of Geriatric Psychiatry, McLean Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Christian Simhandl (C)

Medical Faculty, Bipolar Center Wiener Neustadt, Sigmund Freud University, Wien, Austria.

Jair C Soares (JC)

Teaching Unit of Psychiatry and Psychological Medicine, Department of Medicine, University of Valencia, CIBERSAM, Valencia, Spain.
Faillace Department of Psychiatry and Behavioral Sciences, McGovern Medical School, UTHealth Houston, Texas, USA.

Shang-Ying Tsai (SY)

Department of Psychiatry, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

Eduard Vieta (E)

Bipolar and Depressive Disorders Unit, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Catalonia, Spain.

Luca M Villa (LM)

Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut, USA.
Department of Psychiatry, University of Oxford, Oxford, UK.

Martha Sajatovic (M)

Departments of Psychiatry and of Neurology, Case Western Reserve University School of Medicine, University Hospitals Cleveland Medical Center, Cleveland, Ohio, USA.

Lisa T Eyler (LT)

Department of Psychiatry, University of California San Diego, San Diego, California, USA.
Desert-Pacific Mental Illness Research Education and Clinical Center, VA San Diego Healthcare System, San Diego, California, USA.

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