A Phylogeographic Analysis of Porcine Parvovirus 1 in Africa.
Africa
VP2
epidemiology
phylogeny
phylogeography
porcine parvovirus 1
Journal
Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722
Informations de publication
Date de publication:
11 01 2023
11 01 2023
Historique:
received:
21
11
2022
revised:
05
01
2023
accepted:
08
01
2023
entrez:
21
1
2023
pubmed:
22
1
2023
medline:
25
1
2023
Statut:
epublish
Résumé
Porcine parvovirus 1 (PPV1) is recognized as a major cause of reproductive failure in pigs, leading to several clinical outcomes globally known as SMEDI. Despite being known since the late 1960s its circulation is still of relevance to swine producers. Additionally, the emergence of variants such as the virulent 27a strain, for which lower protection induced by vaccines has been demonstrated, is of increasing concern. Even though constant monitoring of PPV1 using molecular epidemiological approaches is of pivotal importance, viral sequence data are scarce especially in low-income countries. To fill this gap, a collection of 71 partial VP2 sequences originating from eight African countries (Burkina Faso, Côte d'Ivoire, Kenya, Mozambique, Namibia, Nigeria, Senegal, and Tanzania) during the period 2011-2021 were analyzed within the context of global PPV1 variability. The observed pattern largely reflected what has been observed in high-income regions, i.e., 27a-like strains were more frequently detected than less virulent NADL-8-like strains. A phylogeographic analysis supported this observation, highlighting that the African scenario has been largely shaped by multiple PPV1 importation events from other continents, especially Europe and Asia. The existence of such an international movement coupled with the circulation of potential vaccine-escape variants requires the careful evaluation of the control strategies to prevent new strain introduction and persistence.
Identifiants
pubmed: 36680247
pii: v15010207
doi: 10.3390/v15010207
pmc: PMC9864576
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Références
Mol Biol Evol. 2013 Apr;30(4):772-80
pubmed: 23329690
Animals (Basel). 2022 Jun 30;12(13):
pubmed: 35804594
Curr Issues Mol Biol. 2020;37:33-46
pubmed: 31822635
Viruses. 2017 Jul 26;9(8):
pubmed: 28933737
Virus Evol. 2015 May 26;1(1):vev003
pubmed: 27774277
Bioinformatics. 2006 Dec 15;22(24):3096-8
pubmed: 17110367
Aust Vet J. 1993 May;70(5):177-80
pubmed: 8393655
Infect Genet Evol. 2015 Dec;36:300-306
pubmed: 26453771
Virus Evol. 2016 Apr 09;2(1):vew007
pubmed: 27774300
Viruses. 2017 Dec 20;9(12):
pubmed: 29261104
PLoS Comput Biol. 2009 Sep;5(9):e1000520
pubmed: 19779555
Vet Res Commun. 2022 Dec 10;:
pubmed: 36494511
J Gen Virol. 2006 Feb;87(Pt 2):295-301
pubmed: 16432014
J Gen Virol. 2011 Nov;92(Pt 11):2628-2636
pubmed: 21795474
Virus Evol. 2018 Jun 08;4(1):vey016
pubmed: 29942656
Arch Virol. 2021 Jun;166(6):1723-1728
pubmed: 33721098
Infect Genet Evol. 2012 Aug;12(6):1163-71
pubmed: 22575819
Transbound Emerg Dis. 2022 Sep;69(5):e2175-e2184
pubmed: 35403349
Nat Methods. 2012 Jul 30;9(8):772
pubmed: 22847109
Virus Evol. 2022 Jun 16;8(1):veac053
pubmed: 35815310
Arch Virol. 2022 Dec;167(12):2715-2722
pubmed: 36138234
Vet Microbiol. 2013 Jul 26;165(1-2):13-20
pubmed: 23380460
Transbound Emerg Dis. 2022 Jul;69(4):e1142-e1152
pubmed: 34812571
Mol Biol Evol. 2016 Aug;33(8):2167-9
pubmed: 27189542
Mol Biol Evol. 2019 Jul 31;:
pubmed: 31364710
J Gen Virol. 2007 Feb;88(Pt 2):420-427
pubmed: 17251558
J Trop Med. 2022 Sep 28;2022:5185247
pubmed: 36211625
J Gen Virol. 2009 Oct;90(Pt 10):2437-2441
pubmed: 19535504
Mol Biol Evol. 2015 Jan;32(1):268-74
pubmed: 25371430
Mol Biol Evol. 2012 Sep;29(9):2157-67
pubmed: 22403239
J Virol. 1996 Apr;70(4):2508-15
pubmed: 8642680