The association of dietary and lifestyle indices for hyperinsulinemia with odds of non-alcoholic fatty liver disease in Iranian adults: a case-control study.
Adults
Dietary pattern
Insulinemic indices
Lifestyle
Non-alcoholic fatty liver disease
Physical activity
Journal
BMC nutrition
ISSN: 2055-0928
Titre abrégé: BMC Nutr
Pays: England
ID NLM: 101672434
Informations de publication
Date de publication:
20 Jan 2023
20 Jan 2023
Historique:
received:
06
07
2022
accepted:
12
01
2023
entrez:
20
1
2023
pubmed:
21
1
2023
medline:
21
1
2023
Statut:
epublish
Résumé
Evidence on the association of insulinemic effects of dietary pattern and other lifestyle factors with the odds of non-alcoholic fatty liver disease (NAFLD) are limited. In the current study, we aimed to examine the association of the empirical dietary index for hyperinsulinemia (EDIH) and empirical lifestyle index for hyperinsulinemia (ELIH) index with the NAFLD odds in the adult population. In the current case-control study, 120 cases of NAFLD and 240 controls aged 20-60 years were included. The ultrasonography test was used to determine NAFLD. We used a validated food frequency questionnaire to collect dietary data of individuals and determine the scores of EDIH. Also, we determined the ELIH score based on diet, body mass index, and physical activity. The odds ratio (OR) of NAFLD was calculated using logistic regression test across EDIH and ELIH tertiles. The mean ± SD age of subjects (53% men) were 41.8 ± 7.5 years. In the age and sex-adjusted model, there is a significant association between a higher ELIH score and higher odds of NAFLD (OR = 2.74;95%CI:1.51-4.96,P Our results showed that the high insulinemic potential of lifestyle, determined by the ELIH score, can be related to an increased NAFLD odds. However, no significant association was found between higher EDIH score and odds of NAFLD.
Sections du résumé
BACKGROUND
BACKGROUND
Evidence on the association of insulinemic effects of dietary pattern and other lifestyle factors with the odds of non-alcoholic fatty liver disease (NAFLD) are limited. In the current study, we aimed to examine the association of the empirical dietary index for hyperinsulinemia (EDIH) and empirical lifestyle index for hyperinsulinemia (ELIH) index with the NAFLD odds in the adult population.
METHODS
METHODS
In the current case-control study, 120 cases of NAFLD and 240 controls aged 20-60 years were included. The ultrasonography test was used to determine NAFLD. We used a validated food frequency questionnaire to collect dietary data of individuals and determine the scores of EDIH. Also, we determined the ELIH score based on diet, body mass index, and physical activity. The odds ratio (OR) of NAFLD was calculated using logistic regression test across EDIH and ELIH tertiles.
RESULTS
RESULTS
The mean ± SD age of subjects (53% men) were 41.8 ± 7.5 years. In the age and sex-adjusted model, there is a significant association between a higher ELIH score and higher odds of NAFLD (OR = 2.74;95%CI:1.51-4.96,P
CONCLUSIONS
CONCLUSIONS
Our results showed that the high insulinemic potential of lifestyle, determined by the ELIH score, can be related to an increased NAFLD odds. However, no significant association was found between higher EDIH score and odds of NAFLD.
Identifiants
pubmed: 36670457
doi: 10.1186/s40795-023-00675-3
pii: 10.1186/s40795-023-00675-3
pmc: PMC9854092
doi:
Types de publication
Journal Article
Langues
eng
Pagination
16Informations de copyright
© 2023. The Author(s).
Références
Clin Liver Dis. 2018 Feb;22(1):73-92
pubmed: 29128062
Clin Nutr. 2021 Oct;40(10):5373-5382
pubmed: 34560608
J Nutr. 2019 May 1;149(5):804-815
pubmed: 31004153
Lancet Gastroenterol Hepatol. 2021 Dec;6(12):1036-1046
pubmed: 34508671
J Gastroenterol Hepatol. 2011 Mar;26(3):510-6
pubmed: 21155882
World J Gastroenterol. 2011 Aug 7;17(29):3377-89
pubmed: 21876630
Am J Clin Nutr. 2007 Mar;85(3):910-8
pubmed: 17344515
Int J Behav Nutr Phys Act. 2011 Oct 21;8:115
pubmed: 22018588
J Hum Nutr Diet. 2021 Oct;34(5):901-909
pubmed: 33586811
Br J Nutr. 2016 Nov 28;116(10):1787-1798
pubmed: 27821188
Diabetes Care. 2021 Mar;44(3):707-714
pubmed: 33419931
Hepatobiliary Surg Nutr. 2019 Apr;8(2):167-169
pubmed: 31098370
Nutr Rev. 2007 Jun;65(6 Pt 2):S57-63
pubmed: 17605315
Med Sci Sports Exerc. 2000 Sep;32(9 Suppl):S498-504
pubmed: 10993420
Am J Clin Nutr. 2018 Aug 1;108(2):363-370
pubmed: 29901698
Nutr J. 2021 Apr 23;20(1):39
pubmed: 33892738
JNCI Cancer Spectr. 2018 Nov;2(4):pky080
pubmed: 30740588
Liver Int. 2022 Jan;42(1):69-79
pubmed: 34521152
Am J Med. 2011 Jan;124(1):69-76
pubmed: 21187187
Diabetol Metab Syndr. 2021 May 13;13(1):53
pubmed: 33985566
Hepatology. 2009 Jan;49(1):306-17
pubmed: 19065650
Diabetes Care. 2020 Nov;43(11):2675-2683
pubmed: 32873589
J Clin Endocrinol Metab. 2001 May;86(5):1930-5
pubmed: 11344187
Lancet Gastroenterol Hepatol. 2021 Jul;6(7):578-588
pubmed: 33961787