Ambient Air Pollution and Stroke: An Updated Review.
air pollution
lung
nitric oxide
nitrogen dioxide
particulate matter
smoke
stroke
Journal
Stroke
ISSN: 1524-4628
Titre abrégé: Stroke
Pays: United States
ID NLM: 0235266
Informations de publication
Date de publication:
03 2023
03 2023
Historique:
pmc-release:
01
03
2024
pubmed:
30
12
2022
medline:
3
3
2023
entrez:
29
12
2022
Statut:
ppublish
Résumé
Despite recent advances in treatment and prevention, stroke remains a leading cause of morbidity and mortality. There is a critical need to identify novel modifiable risk factors for disease, including environmental agents. A body of evidence has accumulated suggesting that elevated levels of ambient air pollutants may not only trigger cerebrovascular events in susceptible people (short-term exposures) but also increase the risk of future events (long-term average exposures). This review assesses the updated evidence for both short and long-term exposure to ambient air pollution as a risk factor for stroke incidence and outcomes. It discusses the potential pathophysiologic mechanisms and makes recommendations to mitigate exposure on a personal and community level. The evidence indicates that reduction in air pollutant concentrations represent a significant population-level opportunity to reduce risk of cerebrovascular disease.
Identifiants
pubmed: 36579640
doi: 10.1161/STROKEAHA.122.035498
pmc: PMC10421613
mid: NIHMS1849171
doi:
Substances chimiques
Particulate Matter
0
Air Pollutants
0
Nitrogen Dioxide
S7G510RUBH
Types de publication
Journal Article
Review
Research Support, N.I.H., Extramural
Langues
eng
Sous-ensembles de citation
IM
Pagination
882-893Subventions
Organisme : NIEHS NIH HHS
ID : K23 ES030725
Pays : United States
Organisme : NIEHS NIH HHS
ID : P30 ES007033
Pays : United States
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