Severity and progression rate of periodontitis are associated with an increased risk of hypertension of patients attending a university clinic.
Blood pressure
Classification
Hypertension
Oral health
Periodontitis
Public health
Journal
BMC oral health
ISSN: 1472-6831
Titre abrégé: BMC Oral Health
Pays: England
ID NLM: 101088684
Informations de publication
Date de publication:
22 12 2022
22 12 2022
Historique:
received:
06
10
2022
accepted:
30
11
2022
entrez:
22
12
2022
pubmed:
23
12
2022
medline:
27
12
2022
Statut:
epublish
Résumé
Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate are linked with self-reports on doctor-diagnosed hypertension in a large cohort of patients attending the periodontology clinic at the faculty of dentistry. Archived patient files, including radiographic image records and results from full-mouth clinical periodontal examination were screened for inclusion. Data on socioeconomic factors, smoking and oral hygiene habits, and medical history were collected with a questionnaire. Diagnosis and background data were available for 7008 patients. The median (IQR) age was 31.0 (21.0) years; 60.1% (n = 4211) were female. Hypertension was diagnosed in 6.2% (n = 435) of patients. Both periodontitis stage and grade differed (p < 0.001) between patients with or without hypertension. Increased periodontal disease severity was associated with a 20% increasing risk for hypertension; the odds ratio (OR) was 2.63 (95% confidence interval [CI] 1.48-4.68, p < 0.001) in stage IV periodontitis. Increasing periodontitis progression rate was associated with a 35% increased risk for hypertension; the OR was 2.22 (95% CI 1.45-3.40, p < 0.001) in grade C periodontitis. Severity and progression rate of periodontitis may be independent risk factors for hypertension in this large cohort of patients attending the university periodontal department.
Sections du résumé
BACKGROUND
Although periodontitis is associated with increased risk of hypertension, studies based on new periodontal disease classification is limited. We investigated whether periodontitis severity and progression rate are linked with self-reports on doctor-diagnosed hypertension in a large cohort of patients attending the periodontology clinic at the faculty of dentistry.
METHODS
Archived patient files, including radiographic image records and results from full-mouth clinical periodontal examination were screened for inclusion. Data on socioeconomic factors, smoking and oral hygiene habits, and medical history were collected with a questionnaire.
RESULTS
Diagnosis and background data were available for 7008 patients. The median (IQR) age was 31.0 (21.0) years; 60.1% (n = 4211) were female. Hypertension was diagnosed in 6.2% (n = 435) of patients. Both periodontitis stage and grade differed (p < 0.001) between patients with or without hypertension. Increased periodontal disease severity was associated with a 20% increasing risk for hypertension; the odds ratio (OR) was 2.63 (95% confidence interval [CI] 1.48-4.68, p < 0.001) in stage IV periodontitis. Increasing periodontitis progression rate was associated with a 35% increased risk for hypertension; the OR was 2.22 (95% CI 1.45-3.40, p < 0.001) in grade C periodontitis.
CONCLUSION
Severity and progression rate of periodontitis may be independent risk factors for hypertension in this large cohort of patients attending the university periodontal department.
Identifiants
pubmed: 36550459
doi: 10.1186/s12903-022-02637-w
pii: 10.1186/s12903-022-02637-w
pmc: PMC9784004
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
627Subventions
Organisme : Eskisehir Osmangazi University, Eskisehir, Turkey
ID : 202045A221
Informations de copyright
© 2022. The Author(s).
Références
J Periodontol. 2007 Jul;78(7 Suppl):1387-99
pubmed: 17608611
J Clin Periodontol. 2020 Mar;47(3):268-288
pubmed: 32011025
J Hypertens. 2016 Jun;34(6):1208-17
pubmed: 26991534
J Periodontol. 2020 Oct;91(10):1245-1255
pubmed: 32077489
Nat Rev Cardiol. 2021 Nov;18(11):785-802
pubmed: 34050340
J Periodontol. 2018 Jun;89 Suppl 1:S173-S182
pubmed: 29926951
Am J Hypertens. 2014 Nov;27(11):1327-37
pubmed: 25150828
J Periodontol. 2018 Jun;89 Suppl 1:S1-S8
pubmed: 29926946
J Clin Periodontol. 1982 Jul;9(4):323-36
pubmed: 6764782
Curr Hypertens Rep. 2021 May 7;23(5):27
pubmed: 33961166
Lancet. 2018 Nov 10;392(10159):1923-1994
pubmed: 30496105
Eur Heart J. 2019 Nov 1;40(42):3459-3470
pubmed: 31504461
Int J Cardiol. 2014 Nov 15;177(1):202-8
pubmed: 25499379
Ann Med Health Sci Res. 2014 Jul;4(4):549-53
pubmed: 25221702
mSphere. 2018 Oct 17;3(5):
pubmed: 30333180
Cochrane Database Syst Rev. 2021 Dec 12;12:CD009409
pubmed: 34897644
Arch Microbiol. 2022 Feb 23;204(3):192
pubmed: 35195774
Acta Odontol Scand. 1963 Dec;21:533-51
pubmed: 14121956
Biology (Basel). 2021 Mar 27;10(4):
pubmed: 33801728
Cell. 2018 Jun 14;173(7):1728-1741.e13
pubmed: 29804833
Elife. 2019 Feb 12;8:
pubmed: 30747106
Nat Rev Microbiol. 2018 Dec;16(12):745-759
pubmed: 30301974
Curr Cardiol Rev. 2014 Nov;10(4):355-61
pubmed: 24739001
Cardiovasc Res. 2020 Jan 1;116(1):28-39
pubmed: 31549149
Pharmacol Res. 2021 Apr;166:105511
pubmed: 33617973
J Periodontol. 2013 Feb;84(2):203-11
pubmed: 22548584
Acta Odontol Scand. 1964 Feb;22:121-35
pubmed: 14158464
Nutrients. 2021 Aug 24;13(9):
pubmed: 34578783
J Dent Res. 2020 Sep;99(10):1165-1173
pubmed: 32479136
Periodontol 2000. 2022 Jun;89(1):19-40
pubmed: 35244966
JAMA Netw Open. 2019 Apr 5;2(4):e192523
pubmed: 31026022
Nat Genet. 2022 Feb;54(2):134-142
pubmed: 35115689
J Periodontol. 2018 Jun;89 Suppl 1:S159-S172
pubmed: 29926952
J Periodontol. 2022 Jul;93(7):1024-1035
pubmed: 35460076
Am Heart J. 2016 Oct;180:98-112
pubmed: 27659888