Effectiveness of vaccines in preventing hospitalization due to COVID-19: A multicenter hospital-based case-control study, Germany, June 2021 to January 2022.
COVID-19
Case-control study
Delta
Hospitalization
SARS-CoV-2
Vaccine effectiveness
Journal
Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899
Informations de publication
Date de publication:
09 01 2023
09 01 2023
Historique:
received:
10
08
2022
revised:
16
11
2022
accepted:
27
11
2022
pubmed:
13
12
2022
medline:
4
1
2023
entrez:
12
12
2022
Statut:
ppublish
Résumé
We included 852 patients in a prospectively recruiting multicenter matched case-control study in Germany to assess vaccine effectiveness (VE) in preventing COVID-19-associated hospitalization during the Delta-variant dominance. The two-dose VE was 89 % (95 % CI 84-93 %) overall, 79 % in patients with more than two comorbidities and 77 % in adults aged 60-75 years. A third dose increased the VE to more than 93 % in all patient-subgroups.
Identifiants
pubmed: 36509640
pii: S0264-410X(22)01489-X
doi: 10.1016/j.vaccine.2022.11.065
pmc: PMC9715487
pii:
doi:
Substances chimiques
Vaccines
0
Types de publication
Multicenter Study
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
290-293Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: S. G. received payment/honoraria from Astra Zeneca, Boehringer Ingelheim, Roche Pharma and Berlin Chemie, this had no influence on this work; all other authors reported no conflicts of interest.
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