Structural Basis of Cysteine Ligase MshC Inhibition by Cysteinyl-Sulfonamides.
MshC
Mycobacterium tuberculosis
bi-substrate competitive inhibitors
enzyme inhibition
protein-ligand co-crystal structures
structure-activity relationship
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
01 Dec 2022
01 Dec 2022
Historique:
received:
11
11
2022
revised:
25
11
2022
accepted:
26
11
2022
entrez:
11
12
2022
pubmed:
12
12
2022
medline:
15
12
2022
Statut:
epublish
Résumé
Mycothiol (MSH), the major cellular thiol in
Identifiants
pubmed: 36499418
pii: ijms232315095
doi: 10.3390/ijms232315095
pmc: PMC9736012
pii:
doi:
Substances chimiques
Bacterial Proteins
0
Cysteine
K848JZ4886
Glycopeptides
0
Inositol
4L6452S749
Ligases
EC 6.-
Sulfonamides
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Research Foundation - Flanders
ID : G0A4616N
Organisme : Research Foundation - Flanders
ID : G066619N
Organisme : Research Foundation - Flanders
ID : 1S68722N
Organisme : KU Leuven Research Fund
ID : 3M14022
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