Integrated survey of helminthic neglected tropical diseases and comparison of two mosquito sampling methods for lymphatic filariasis molecular xenomonitoring in the River Galana area, Kilifi County, coastal Kenya.
Journal
PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081
Informations de publication
Date de publication:
2022
2022
Historique:
received:
08
04
2022
accepted:
21
11
2022
entrez:
9
12
2022
pubmed:
10
12
2022
medline:
15
12
2022
Statut:
epublish
Résumé
A lymphatic filariasis (LF) endemic focus along the River Galana/ Sabaki in Kilifi County, coastal Kenya, provided a platform to conduct an integrated survey for three helminthic neglected tropical diseases (NTDs), namely soil-transmitted helminthiasis (STH), schistosomiasis (SCH) and LF. Additionally, the study compared the performance of two mosquito trapping methods for LF molecular xenomonitoring (MX). Cross-sectional surveys measuring STH, SCH and LF prevalence were conducted in four villages. Mosquitoes were trapped using the CDC light trap (CDC-LT) and the Ifakara A tent trap (Ifakara-TT) methods and stored in pools which were tested for Wuchereria bancrofti DNA using the real-time polymerase chain reaction assay. A total of 907 people (436 adults; 471 children) participated in the parasitological testing. Among the STH infections, Trichuris trichiura and hookworms were most prevalent among the children and adult populations, respectively. The schistosome worm eggs detected belonged to the species Schistosoma haematobium and the prevalence of the infection was generally higher among the children compared with the adult population. The prevalence of LF infection among the adult population ranged from 1.8% to 7.6% across all 4 villages (P < 0.05). A total of 3,652 mosquitoes, including Anopheles, Culex, Mansonia, and Aedes species were collected. One mosquito pool consisting of Anopheles mosquitoes tested positive for filarial DNA out of 1,055 pools that were tested. The CDC-LT caught significantly more mosquitoes compared with the Ifakara-TT (P < 0.001). This study demonstrated that integrated epidemiological surveys using standard parasitological and entomological methods can provide useful information on co-endemic parasitic diseases which could help direct interventions and surveillance activities.
Identifiants
pubmed: 36490233
doi: 10.1371/journal.pone.0278655
pii: PONE-D-22-10379
pmc: PMC9733851
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0278655Informations de copyright
Copyright: © 2022 Njenga et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Clin Infect Dis. 2021 Jun 14;72(Suppl 3):S203-S209
pubmed: 33906238
Trans R Soc Trop Med Hyg. 2013 Jan;107(1):15-22
pubmed: 23222942
Am J Trop Med Hyg. 2021 Nov 22;106(2):700-709
pubmed: 34814104
Clin Infect Dis. 2019 Jan 1;68(1):96-105
pubmed: 29788074
PLoS Negl Trop Dis. 2016 May 19;10(5):e0004722
pubmed: 27196431
PLoS Med. 2005 Nov;2(11):e336
pubmed: 16212468
Malar J. 2016 Apr 26;15:239
pubmed: 27113244
Bull World Health Organ. 1997;75(6):491-503
pubmed: 9509621
Malar J. 2015 Dec 15;14:502
pubmed: 26670881
Trans R Soc Trop Med Hyg. 2007 May;101(5):439-44
pubmed: 17145069
BMJ. 2017 Sep 25;358:j4307
pubmed: 28947636
PLoS Negl Trop Dis. 2013 Dec 12;7(12):e2586
pubmed: 24349595
Trans R Soc Trop Med Hyg. 2008 Oct;102(10):1017-24
pubmed: 18550135
Ann Trop Med Parasitol. 2007 Mar;101(2):161-72
pubmed: 17316502
Parasit Vectors. 2012 May 07;5:89
pubmed: 22564488
Am J Trop Med Hyg. 2010 Sep;83(3):596-600
pubmed: 20810826
Ann Trop Med Parasitol. 1979 Oct;73(5):457-64
pubmed: 393190
Trends Parasitol. 2018 Aug;34(8):694-711
pubmed: 29958813
Parasit Vectors. 2012 Nov 14;5:259
pubmed: 23151383
J Theor Biol. 2017 Nov 7;432:87-99
pubmed: 28823529
Parasitol Res. 2012 Jan;110(1):61-71
pubmed: 21626425
PLoS Negl Trop Dis. 2018 Aug 2;12(8):e0006563
pubmed: 30071014
PLoS Negl Trop Dis. 2020 Jun 23;14(6):e0008322
pubmed: 32574160
Acta Trop. 2000 Oct 23;77(1):41-51
pubmed: 10996119
Commun Biol. 2023 Feb 27;6(1):225
pubmed: 36849730
Trop Med Int Health. 2010 Feb;15(2):198-207
pubmed: 20409287
Parasit Vectors. 2011 May 25;4:90
pubmed: 21612649
Ann Trop Med Parasitol. 1977 Sep;71(3):313-31
pubmed: 335990
Parasit Vectors. 2011 Sep 14;4:175
pubmed: 21917166
PLoS Negl Trop Dis. 2014 Nov 13;8(11):e3281
pubmed: 25393404
J Am Mosq Control Assoc. 1988 Dec;4(4):536-8
pubmed: 3066845
PLoS Negl Trop Dis. 2020 May 12;14(5):e0008289
pubmed: 32396575
Trop Med Int Health. 2003 Feb;8(2):100-8
pubmed: 12581433
Malar J. 2009 Jul 14;8:157
pubmed: 19602253
World Health Organ Tech Rep Ser. 2002;912:i-vi, 1-57, back cover
pubmed: 12592987
Am J Trop Med Hyg. 2006 May;74(5):826-32
pubmed: 16687688