Moderate activity of RNA chaperone maximizes the yield of self-spliced pre-RNA in vivo.

ATP consumption iterative annealing mechanism kinetic partitioning mechanism self-splicing activity thermodynamic cost

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
06 12 2022
Historique:
entrez: 28 11 2022
pubmed: 29 11 2022
medline: 1 12 2022
Statut: ppublish

Résumé

CYT-19 is a DEAD-box protein whose adenosine-triphosphate (ATP)-dependent helicase activity facilitates the folding of group I introns in precursor RNA (pre-RNA) of

Identifiants

pubmed: 36442111
doi: 10.1073/pnas.2209422119
pmc: PMC9894238
doi:

Substances chimiques

RNA Precursors 0
RNA, Catalytic 0
RNA 63231-63-0
Adenosine Triphosphate 8L70Q75FXE

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2209422119

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Auteurs

Yonghyun Song (Y)

Korea Institute for Advanced Study, Seoul 02455, Korea.

D Thirumalai (D)

Department of Chemistry, The University of Texas at Austin, Austin, TX 78712.

Changbong Hyeon (C)

Korea Institute for Advanced Study, Seoul 02455, Korea.

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Classifications MeSH