Population Genetics of the European Roma-A Review.

Romani bottleneck founder event genetic structure genomics population genetics

Journal

Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097

Informations de publication

Date de publication:
08 11 2022
Historique:
received: 06 10 2022
revised: 27 10 2022
accepted: 03 11 2022
entrez: 11 11 2022
pubmed: 12 11 2022
medline: 15 11 2022
Statut: epublish

Résumé

The Roma are a group of populations with a common origin that share the Romani identity and cultural heritage. Their genetic history has been inferred through multiple studies based on uniparental and autosomal markers, and current genomic data have provided novel insights into their genetic background. This review was prompted by two factors: (i) new developments to estimate the genetic structure of the Roma at a fine-scale resolution have precisely identified the ancestral components and traced migrations that were previously documented only in historical sources, clarifying and solving debates on the origins and the diaspora of the Roma; (ii) while there has been an effort to review the health determinants of the Roma, the increasing literature on their population genetics has not been subjected to a dedicated review in the last two decades. We believe that a summary on the state of the art will benefit both the public and scholars that are approaching the subject.

Identifiants

pubmed: 36360305
pii: genes13112068
doi: 10.3390/genes13112068
pmc: PMC9690732
pii:
doi:

Types de publication

Journal Article Review Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Giacomo Francesco Ena (GF)

Department of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, Spain.

Julen Aizpurua-Iraola (J)

Department of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, Spain.

Neus Font-Porterias (N)

Department of Biomedical Informatics, Anschutz Medical Campus, University of Colorado, Aurora, CO 80309, USA.

Francesc Calafell (F)

Department of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, Spain.

David Comas (D)

Department of Medicine and Life Sciences (MELIS), Institute of Evolutionary Biology (CSIC-UPF), Universitat Pompeu Fabra, 08002 Barcelona, Spain.

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Classifications MeSH