Clinical Performance of Three Commercial Molecular Diagnostic Assays for the Detection of Fluoroquinolone Resistance-Associated Mutations in Mycoplasma genitalium.


Journal

Journal of clinical microbiology
ISSN: 1098-660X
Titre abrégé: J Clin Microbiol
Pays: United States
ID NLM: 7505564

Informations de publication

Date de publication:
21 12 2022
Historique:
pubmed: 3 11 2022
medline: 24 12 2022
entrez: 2 11 2022
Statut: ppublish

Résumé

The high prevalence of macrolide resistance in Mycoplasma genitalium results in an increased reliance on moxifloxacin, the second-line treatment; however, moxifloxacin resistance has also emerged. Because assays that can detect fluoroquinolone resistance-associated mutations will be useful for the management of macrolide-resistant M. genitalium infections, we evaluated the performance of three commercial assays (the Allplex MG & MoxiR Assay [Seegene], LightMix Modular parC kit [TIBMOLBIOL], and MGMO qPCR [NYtor) in comparison with

Identifiants

pubmed: 36321820
doi: 10.1128/jcm.01135-22
pmc: PMC9769504
doi:

Substances chimiques

Fluoroquinolones 0
Anti-Bacterial Agents 0
Moxifloxacin U188XYD42P
Macrolides 0
RNA, Ribosomal, 23S 0
DNA, Bacterial 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0113522

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Auteurs

Marie Gardette (M)

CHU Bordeaux, Bacteriology Department, National Reference Center for Bacterial Sexually Transmitted Infections, Bordeaux, France.

Nadège Hénin (N)

University of Bordeauxgrid.412041.2, CNRS, Fundamental Microbiology and Pathogenicity, UMR 5234, Bordeaux, France.

Chloé Le Roy (C)

University of Bordeauxgrid.412041.2, CNRS, Fundamental Microbiology and Pathogenicity, UMR 5234, Bordeaux, France.

Jennifer Guiraud (J)

CHU Bordeaux, Bacteriology Department, National Reference Center for Bacterial Sexually Transmitted Infections, Bordeaux, France.
University of Bordeauxgrid.412041.2, CNRS, Fundamental Microbiology and Pathogenicity, UMR 5234, Bordeaux, France.

Arabella Touati (A)

CHU Bordeaux, Bacteriology Department, National Reference Center for Bacterial Sexually Transmitted Infections, Bordeaux, France.

Cécile Bébéar (C)

CHU Bordeaux, Bacteriology Department, National Reference Center for Bacterial Sexually Transmitted Infections, Bordeaux, France.
University of Bordeauxgrid.412041.2, CNRS, Fundamental Microbiology and Pathogenicity, UMR 5234, Bordeaux, France.

Sabine Pereyre (S)

CHU Bordeaux, Bacteriology Department, National Reference Center for Bacterial Sexually Transmitted Infections, Bordeaux, France.
University of Bordeauxgrid.412041.2, CNRS, Fundamental Microbiology and Pathogenicity, UMR 5234, Bordeaux, France.

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Classifications MeSH