Surgical resection of a tuberculoma in the diaphragm: a case report.
Diaphragm
Extrapulmonary tuberculosis
Paradoxical reaction
Tuberculoma
Journal
Surgical case reports
ISSN: 2198-7793
Titre abrégé: Surg Case Rep
Pays: Germany
ID NLM: 101662125
Informations de publication
Date de publication:
14 Oct 2022
14 Oct 2022
Historique:
received:
17
12
2021
accepted:
10
10
2022
entrez:
14
10
2022
pubmed:
15
10
2022
medline:
15
10
2022
Statut:
epublish
Résumé
Extrapulmonary tuberculosis commonly affects the lymphatic system, nervous system, and gastrointestinal system. Tuberculous infection in the muscle is very rare. Moreover, tuberculous infection in the diaphragm is extremely rare. We herein report a case of tuberculomas in the diaphragm and posterior mediastinum that were successfully diagnosed and treated. We encountered a 62-year-old woman with a tuberculoma in the diaphragm. The patient presented with mild dyspnea. Computed tomography showed a mass in the left diaphragm, focal thickening of the posterior mediastinum, and multiple nodules in the lungs. Positron emission tomography-computed tomography showed increased uptake in the left diaphragm mass and thickening of the posterior mediastinum; therefore, we considered the masses to be malignant and planned surgical resection. However, the patient was diagnosed with tuberculosis from a sputum culture, and she was treated with anti-tuberculous therapy. The masses in the diaphragm and posterior mediastinum had become enlarged after 6 months of anti-tuberculous therapy; therefore, the patient underwent resection of both masses. Tuberculous infection was histologically confirmed in each lesion. She was pathologically diagnosed with tuberculous abscesses in the diaphragm and posterior mediastinum and began treatment with anti-tuberculosis drugs. Preoperative diagnosis of a tuberculoma in the diaphragm is usually difficult, and surgical intervention is important for both diagnosis and treatment.
Sections du résumé
BACKGROUND
BACKGROUND
Extrapulmonary tuberculosis commonly affects the lymphatic system, nervous system, and gastrointestinal system. Tuberculous infection in the muscle is very rare. Moreover, tuberculous infection in the diaphragm is extremely rare. We herein report a case of tuberculomas in the diaphragm and posterior mediastinum that were successfully diagnosed and treated.
CASE PRESENTATION
METHODS
We encountered a 62-year-old woman with a tuberculoma in the diaphragm. The patient presented with mild dyspnea. Computed tomography showed a mass in the left diaphragm, focal thickening of the posterior mediastinum, and multiple nodules in the lungs. Positron emission tomography-computed tomography showed increased uptake in the left diaphragm mass and thickening of the posterior mediastinum; therefore, we considered the masses to be malignant and planned surgical resection. However, the patient was diagnosed with tuberculosis from a sputum culture, and she was treated with anti-tuberculous therapy. The masses in the diaphragm and posterior mediastinum had become enlarged after 6 months of anti-tuberculous therapy; therefore, the patient underwent resection of both masses. Tuberculous infection was histologically confirmed in each lesion. She was pathologically diagnosed with tuberculous abscesses in the diaphragm and posterior mediastinum and began treatment with anti-tuberculosis drugs.
CONCLUSIONS
CONCLUSIONS
Preoperative diagnosis of a tuberculoma in the diaphragm is usually difficult, and surgical intervention is important for both diagnosis and treatment.
Identifiants
pubmed: 36239874
doi: 10.1186/s40792-022-01554-y
pii: 10.1186/s40792-022-01554-y
pmc: PMC9568637
doi:
Types de publication
Journal Article
Langues
eng
Pagination
198Informations de copyright
© 2022. The Author(s).
Références
Respirol Case Rep. 2020 Sep 09;8(8):e00658
pubmed: 32995009
Thorax. 2004 Aug;59(8):704-7
pubmed: 15282393
J Natl Med Assoc. 1990 Oct;82(10):733-6
pubmed: 2280425
Infection. 2013 Apr;41(2):537-43
pubmed: 23203899
Ann Thorac Surg. 2005 Mar;79(3):964-7
pubmed: 15734414
Clin Infect Dis. 2002 Aug 15;35(4):409-13
pubmed: 12145724
Radiographics. 2019 Nov-Dec;39(7):2023-2037
pubmed: 31697616
Mol Clin Oncol. 2016 Jul;5(1):210-212
pubmed: 27330800