Synthesis and Characterization of a Novel Dual-Responsive Nanogel for Anticancer Drug Delivery.
Journal
Oxidative medicine and cellular longevity
ISSN: 1942-0994
Titre abrégé: Oxid Med Cell Longev
Pays: United States
ID NLM: 101479826
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
07
2022
accepted:
03
09
2022
entrez:
4
10
2022
pubmed:
5
10
2022
medline:
6
10
2022
Statut:
epublish
Résumé
In this study, to reduce the side effects of anticancer drugs and also to increase the efficiency of current drug delivery systems, a pH and temperature-responsive polymeric nanogel was synthesized by copolymerization of N-vinylcaprolactam (VCL) and acrylic acid (AA) monomers (P(VCL-co-AA)) with a novel cross-linker, triethylene glycol dimethacrylate (TEGDMA), as a biocompatible and nontoxic component. The structural and physicochemical features of the P(VCL-co-AA) nanogel were characterized by FT-IR, DLS/Zeta potential, FE-SEM, and
Identifiants
pubmed: 36193087
doi: 10.1155/2022/1548410
pmc: PMC9526620
doi:
Substances chimiques
Antineoplastic Agents
0
Drug Carriers
0
Nanogels
0
polyethylene glycol polyethyleneimine nanogel
0
Polyethylene Glycols
3WJQ0SDW1A
Carbon
7440-44-0
Doxorubicin
80168379AG
Polyethyleneimine
9002-98-6
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1548410Informations de copyright
Copyright © 2022 Darya Aminoleslami et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest regarding the publication of this paper.
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