Evaluating polymeric biomaterials to improve next generation wound dressing design.

Biomaterials Polymers Tissue Engineering Wound Dressings Wound Healing

Journal

Biomaterials research
ISSN: 1226-4601
Titre abrégé: Biomater Res
Pays: England
ID NLM: 101650636

Informations de publication

Date de publication:
01 Oct 2022
Historique:
received: 19 02 2022
accepted: 28 08 2022
entrez: 1 10 2022
pubmed: 2 10 2022
medline: 2 10 2022
Statut: epublish

Résumé

Wound healing is a dynamic series of interconnected events with the ultimate goal of promoting neotissue formation and restoration of anatomical function. Yet, the complexity of wound healing can often result in development of complex, chronic wounds, which currently results in a significant strain and burden to our healthcare system. The advancement of new and effective wound care therapies remains a critical issue, with the current therapeutic modalities often remaining inadequate. Notably, the field of tissue engineering has grown significantly in the last several years, in part, due to the diverse properties and applications of polymeric biomaterials. The interdisciplinary cohesion of the chemical, biological, physical, and material sciences is pertinent to advancing our current understanding of biomaterials and generating new wound care modalities. However, there is still room for closing the gap between the clinical and material science realms in order to more effectively develop novel wound care therapies that aid in the treatment of complex wounds. Thus, in this review, we discuss key material science principles in the context of polymeric biomaterials, provide a clinical breadth to discuss how these properties affect wound dressing design, and the role of polymeric biomaterials in the innovation and design of the next generation of wound dressings.

Identifiants

pubmed: 36183134
doi: 10.1186/s40824-022-00291-5
pii: 10.1186/s40824-022-00291-5
pmc: PMC9526981
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

50

Informations de copyright

© 2022. The Author(s).

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Auteurs

Jacob G Hodge (JG)

Bioengineering Graduate Program, University of Kansas, Lawrence, KS, USA.
Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, KS, USA.

David S Zamierowski (DS)

Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, KS, USA.

Jennifer L Robinson (JL)

Department of Chemical and Petroleum Engineering, University of Kansas, Mail Stop: 3051, 3901 Rainbow Blvd, Lawrence, KS, 66160, USA.

Adam J Mellott (AJ)

Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, KS, USA. amellott@kumc.edu.

Classifications MeSH