Idiopathic Multicentric Castleman Disease with Cutaneous Manifestation: Case Report.
Castleman disease
case report
cutaneous manifestation
idiopathic
lymphoproliferative disorders
plasmacytic variant
Journal
Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208
Informations de publication
Date de publication:
05 Sep 2022
05 Sep 2022
Historique:
received:
28
07
2022
revised:
28
08
2022
accepted:
02
09
2022
entrez:
23
9
2022
pubmed:
24
9
2022
medline:
28
9
2022
Statut:
epublish
Résumé
Castleman disease constitutes a rare class of lymphoproliferative disorders, with an estimated incidence of 21 to 25 per million patient years. The idiopathic subtype exhibits a significantly diverse clinical presentation, which can imitate many autoimmune, malignant, and infectious diseases. Cutaneous manifestations are uncommon and require in-depth investigation, especially when concurrent lymphadenopathy is present. A 79-year-old female, with a chronic, complicated erysipelas-like lesion, presented with bilaterally enlarged inguinal lymph nodes; after surgical excision, their histopathological examination revealed Castleman disease. Even though it is a benign condition, patients are often predisposed to developing certain types of malignancies, which can deteriorate their prognosis. An accurate and early diagnosis, along with effective treatment and prevention of recurrence, is of utmost importance in order to increase the patients' overall survival and quality of life.
Identifiants
pubmed: 36143899
pii: medicina58091222
doi: 10.3390/medicina58091222
pmc: PMC9505402
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
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