Gene drive mosquitoes can aid malaria elimination by retarding


Journal

Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440

Informations de publication

Date de publication:
23 09 2022
Historique:
entrez: 21 9 2022
pubmed: 22 9 2022
medline: 24 9 2022
Statut: ppublish

Résumé

Gene drives hold promise for the genetic control of malaria vectors. The development of vector population modification strategies hinges on the availability of effector mechanisms impeding parasite development in transgenic mosquitoes. We augmented a midgut gene of the malaria mosquito

Identifiants

pubmed: 36129981
doi: 10.1126/sciadv.abo1733
pmc: PMC9491717
doi:

Substances chimiques

Magainins 0
Melitten 20449-79-0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

eabo1733

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Auteurs

Astrid Hoermann (A)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Tibebu Habtewold (T)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Prashanth Selvaraj (P)

Institute for Disease Modeling, Bill and Melinda Gates Foundation, Seattle, WA 98109, USA.

Giuseppe Del Corsano (G)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Paolo Capriotti (P)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Maria Grazia Inghilterra (MG)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Temesgen M Kebede (TM)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

George K Christophides (GK)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

Nikolai Windbichler (N)

Department of Life Sciences, Imperial College London, London SW7 2AZ, UK.

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Classifications MeSH