Fluorescent Indocyanine Green versus Technetium-99m and Blue Dye for Bilateral SENTinel Lymph Node Detection in Stage I-IIA Cervical Cancer (FluoreSENT): protocol for a non-inferiority study.
Diagnostic radiology
GYNAECOLOGY
Gynaecological oncology
Nuclear radiology
ONCOLOGY
Journal
BMJ open
ISSN: 2044-6055
Titre abrégé: BMJ Open
Pays: England
ID NLM: 101552874
Informations de publication
Date de publication:
13 09 2022
13 09 2022
Historique:
entrez:
13
9
2022
pubmed:
14
9
2022
medline:
16
9
2022
Statut:
epublish
Résumé
Nowadays, two predominant methods for detecting sentinel lymph nodes (SLNs) in cervical cancer are in use. The most conventional method is a combination of a radiotracer, technetium-99m ( We initiated a prospective non-inferiority study with a paired comparison of both SLN methods in a single sample of 101 patients with International Federation of Gynecology and Obstetrics (FIGO) stage IA-IB2 or IIA1 cervical cancer receiving primary surgical treatment. All patients undergo SLN mapping with ICG and NIR fluorescence imaging in adjunct to mapping with The current study is approved by the Medical Ethics Research Committee Utrecht (reference number 21-014). Findings arising from this study will be disseminated in peer-reviewed journals, academic conferences and through patient organisations. NL9011 and EudraCT 2020-005134-15.
Identifiants
pubmed: 36100304
pii: bmjopen-2022-061829
doi: 10.1136/bmjopen-2022-061829
pmc: PMC9472172
doi:
Substances chimiques
Coloring Agents
0
Technetium
7440-26-8
Indocyanine Green
IX6J1063HV
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e061829Informations de copyright
© Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
Déclaration de conflit d'intérêts
Competing interests: RPZ is a proctor for robot-assisted surgery in gynaecological oncology on behalf of Intuitive Surgical.
Références
World J Surg. 2015 May;39(5):1069-79
pubmed: 25522896
Gynecol Oncol. 2020 Feb;156(2):335-340
pubmed: 31780237
Ann Surg Oncol. 2016 Oct;23(11):3749-3756
pubmed: 27160526
Gynecol Oncol. 2017 Aug;146(2):234-239
pubmed: 28528918
World J Surg Oncol. 2018 Mar 9;16(1):52
pubmed: 29523141
Lancet Oncol. 2018 Oct;19(10):1394-1403
pubmed: 30143441
Gynecol Oncol. 2012 Jan;124(1):78-82
pubmed: 21996262
J Clin Oncol. 2011 May 1;29(13):1686-91
pubmed: 21444878
Lasers Surg Med. 2018 Dec;50(10):994-1001
pubmed: 29968916
Ann Surg Oncol. 2016 Aug;23(8):2522-8
pubmed: 26905542
Gynecol Oncol. 2015 Jun;137(3):436-42
pubmed: 25870917
Cancer. 2011 Nov 1;117(21):4812-22
pubmed: 21484779
Gynecol Oncol. 2014 May;133(2):274-7
pubmed: 24582865
Eur J Cancer. 2019 Jul;116:77-85
pubmed: 31181536
Gynecol Oncol. 2013 May;129(2):389-94
pubmed: 23454644
JAMA Surg. 2021 Feb 1;156(2):157-164
pubmed: 33175109
Gynecol Oncol. 2020 Jan;156(1):93-99
pubmed: 31839343
Ann Surg Oncol. 2008 Oct;15(10):2862-6
pubmed: 18696155
Int J Gynecol Cancer. 2019 May;29(4):829-834
pubmed: 30898938
Cancer Rep (Hoboken). 2022 Jan;5(1):e1401
pubmed: 33973745
Expert Rev Anticancer Ther. 2013 Jul;13(7):861-70
pubmed: 23875664
Gynecol Oncol. 2012 Dec;127(3):462-6
pubmed: 22943880
Gynecol Oncol. 2015 Sep;138(3):542-7
pubmed: 26095896
Gynecol Oncol. 2014 Dec;135(3):606-13
pubmed: 25124160
Gynecol Oncol. 2016 Nov;143(2):302-306
pubmed: 27526991
Gynecol Oncol. 2015 Dec;139(3):559-67
pubmed: 26416173
Mol Imaging Biol. 2011 Oct;13(5):1043-9
pubmed: 20835767
Lancet Oncol. 2017 Mar;18(3):384-392
pubmed: 28159465
Eur Urol. 2014 Dec;66(6):991-8
pubmed: 25092539
Gynecol Oncol. 2012 Mar;124(3):496-501
pubmed: 22120175
Ann Intern Med. 2013 Feb 5;158(3):200-7
pubmed: 23295957
Int J Gynecol Cancer. 2018 May;28(4):641-655
pubmed: 29688967
Gynecol Oncol. 2017 Apr;145(1):96-101
pubmed: 28188015
Gynecol Oncol. 2007 Sep;106(3):604-13
pubmed: 17628644
Eur J Nucl Med Mol Imaging. 2017 Oct;44(11):1853-1861
pubmed: 28492965
Int J Gynaecol Obstet. 2019 Apr;145(1):129-135
pubmed: 30656645
Gynecol Oncol. 2012 Oct;127(1):126-30
pubmed: 22796548
Gynecol Oncol. 2005 Aug;98(2):281-8
pubmed: 15961145
Stat Med. 2002 Jan 30;21(2):231-45
pubmed: 11782062
Gynecol Oncol. 2009 Aug;114(2):375-6
pubmed: 19446867
J Cancer Res Clin Oncol. 2017 Oct;143(10):2039-2048
pubmed: 28828528
Int J Gynecol Cancer. 2019 Jan;29(1):212-215
pubmed: 30640706
N Engl J Med. 2018 Nov 15;379(20):1895-1904
pubmed: 30380365