Biopsychosocial factors associated with complications in patients with frostbite.


Journal

Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R

Informations de publication

Date de publication:
26 Aug 2022
Historique:
entrez: 31 8 2022
pubmed: 1 9 2022
medline: 2 9 2022
Statut: ppublish

Résumé

Cold weather injuries can be devastating and life changing. Biopsychosocial factors such as homelessness and mental illness (especially substance use disorders [SUDs]) are known risk factors for incurring frostbite. Based on clinical experience in an urban level 1 trauma center, we hypothesized that complications following frostbite injury would be influenced by homelessness, SUDs, and other forms of mental illness. The aim of this study was to examine the relationship between biopsychosocial factors and both amputations and unplanned hospital readmissions after cold injuries. Patients admitted with a diagnosis of frostbite between the winters of 2009 and 2018 were included in this retrospective cohort study. Descriptive statistics and multivariable regression assessed factors associated with outcomes of interest. Of the 148 patients in the study, 40 had unplanned readmissions within 1 year. Readmitted patients were significantly less likely to have a stable living situation (48.7% vs 75.0%, P = .005) and more likely to have an SUD (85.0% vs 60.2%, P = .005) or other psychiatric disorder (70.0% vs 50.9%, P = .042). Homelessness and SUDs were independent predictors of unplanned readmission. Overall, 18% of frostbite injuries resulted in amputation. Any history of drug and/or alcohol use independently predicted amputations. The study results suggest that additional hospital and community resources may need to be marshaled to prevent vulnerable patients with biopsychosocial risk factors from having complications after frostbite. Complications place a high downstream burden on healthcare systems. Clinicians caring for frostbite patients with comorbid conditions can use these findings to inform care and discharge decisions.

Identifiants

pubmed: 36042625
doi: 10.1097/MD.0000000000030211
pii: 00005792-202208260-00044
pmc: PMC9410586
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e30211

Informations de copyright

Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.

Déclaration de conflit d'intérêts

The authors have no funding and conflicts of interest to disclose.

Références

Heil K, Thomas R, Robertson G, et al. Freezing and non-freezing cold weather injuries: a systematic review. Br Med Bull. 2016;117:79–93.
Urschel JD. Frostbite: predisposing factors and predictors of poor outcome. J Trauma. 1990;30:340–2.
Koljonen V, Andersson K, Mikkonen K, et al. Frostbite injuries treated in the Helsinki area from 1995 to 2002. J Trauma. 2004;57:1315–20.
Nygaard RM, Endorf FW. Frostbite vs burns: increased cost of care and use of hospital resources. J Burn Care Res. 2018;39:676–9.
Endorf FW, Nygaard RM. High cost and resource utilization of frostbite readmissions in the United States. J Burn Care Res. 2021;42:857–64.
Mäkinen TM, Jokelainen J, Näyhä S, et al. Occurrence of frostbite in the general population—work-related and individual factors. Scand J Work Environ Health. 2009;35:384–93.
Brunette DD, McVaney K. Hypothermic cardiac arrest: an 11 year review of ED management and outcome. Am J Emerg Med. 2000;18:418–22.
Song X, Wang S, Hu Y, et al. Impact of ambient temperature on morbidity and mortality: an overview of reviews. Sci Total Environ. 2017;586:241–54.
Anderson W, White V, Finney A. Coping with low incomes and cold homes. Energy Policy. 2012;49:40–52.
Antti-Poika I, Pohjolainen T, Alaranta H. Severe frostbite of the upper extremities—a psychosocial problem mostly associated with alcohol abuse. Scand J Soc Med. 1990;18:59–61.
National Coalition for the Homeless. Mental illness and homelessness. July 2009. Available at: http://www.nationalhomeless.org/factsheets/Mental_Illness.pdf [access date September 20, 2021].
Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis. 1987;40:373–83.
Sundararajan V, Henderson T, Perry C, et al. New ICD-10 version of the Charlson comorbidity index predicted in-hospital mortality. J Clin Epidemiol. 2004;57:1288–94.
Bannay A, Chaignot C, Blotière PO, et al. The best use of the Charlson comorbidity index with electronic health care database to predict mortality. Med Care. 2016;54:188–94.
Foray J. Mountain frostbite. Current trends in prognosis and treatment (from results concerning 1261 cases). Int J Sports Med. 1992;13(Suppl 1):S193–6.
Cappaert TA, Stone JA, Castellani JW, et al. National Athletic Trainers’ Association position statement: environmental cold injuries. J Athl Train. 2008;43:640–58.
Reamy BV. Frostbite: review and current concepts. J Am Board Fam Pract. 1998;11:34–40.
Handford C, Buxton P, Russell K, et al. Frostbite: a practical approach to hospital management. Extrem Physiol Med. 2014;3:7.
Pinzur MS, Weaver FM. Is urban frostbite a psychiatric disorder? Orthopedics. 1997;20:43–5.
Hudson A, Al Youha S, Samargandi OA, et al. Pre-existing psychiatric disorder in the burn patient is associated with worse outcomes. Burns. 2017;43:973–82.
Davis LE, Bogner E, Coburn NG, et al. Stage at diagnosis and survival in patients with cancer and a pre-existing mental illness: a meta-analysis. J Epidemiol Community Health. 2020;74:84–94.
Haupt E, Vincent HK, Harris A, et al. Pre-injury depression and anxiety in patients with orthopedic trauma and their treatment. Injury. 2018;49:1079–84.
Sturgis R, Sirgany A, Stoops M, et al. Winter homeless services: bringing our neighbors in from the cold. National Coalition for the Homeless. 2010. Available at: http://www.nationalhomeless.org/publications/winter_weather/Winter_weather_report.pdf [access date September 20, 2021].
Rehou S, Mason S, MacDonald J, et al. The influence of substance misuse on clinical outcomes following burn. Burns. 2017;43:1493–8.
Klifto KM, Shetty PN, Slavin BR, et al. Impact of nicotine/smoking, alcohol, and illicit substance use on outcomes and complications of burn patients requiring hospital admission: systematic review and meta-analysis. Burns. 2019;46:1498–24.
Twomey JA, Peltier GL, Zera RT. An open-label study to evaluate the safety and efficacy of tissue plasminogen activator in treatment of severe frostbite. J Trauma. 2005;59:1350–54.
Gonzaga T, Jenabzadeh K, Anderson CP, et al. Use of intra-arterial thrombolytic therapy for acute treatment of frostbite in 62 patients with review of thrombolytic therapy in frostbite. J Burn Care Res. 2016;37:e323–34.
Bruen KJ, Ballard JR, Morris SE, et al. Reduction of the incidence of amputation in frostbite injury with thrombolytic therapy. Arch Surg. 2007;142:546–551.
Heard J, Shamrock A, Galet C, et al. Thrombolytic use in management of frostbite injuries: eight year retrospective review at a single institution. J Burn Care Res. 2020;41:722–6.
Nygaard RM, Lacey AM, Lemere A, et al. Time matters in severe frostbite: assessment of limb/digit salvage on the individual patient level. J Burn Care Res. 2017;38:53–9.
Ungvari Z, Tarantini S, Donato AJ, et al. Mechanisms of vascular aging. Circ Res. 2018;123:849–67.
Nygaard RM, Whitley AB, Fey RM, et al. The Hennepin score: quantification of frostbite management efficacy. J Burn Care Res. 2016;37:e317–22.
Lacey AM, Fey RM, Gayken JR, et al. Microangiography: an alternative tool for assessing severe frostbite injury. J Burn Care Res. 2019;40:566–9.

Auteurs

Frederick W Endorf (FW)

Department of Surgery, Hennepin Healthcare, Minneapolis, MN, USA.

Deepak Alapati (D)

Department of Psychiatry, Hennepin Healthcare, Minneapolis, MN, USA.

Yee Xiong (Y)

Department of Psychiatry, Hennepin Healthcare, Minneapolis, MN, USA.

Cynthia DiGiandomenico (C)

Department of Psychiatry, Hennepin Healthcare, Minneapolis, MN, USA.

Courtney S Rasimas (CS)

School of Public Health, University of Minnesota, Minneapolis, MN, USA.

Joseph J Rasimas (JJ)

Department of Psychiatry, Hennepin Healthcare, Minneapolis, MN, USA.

Rachel M Nygaard (RM)

Department of Surgery, Hennepin Healthcare, Minneapolis, MN, USA.

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