Mapping brain mechanical property maturation from childhood to adulthood.
Cortex
Damping ratio
Development
Elastography
Stiffness
Viscoelasticity
Journal
NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515
Informations de publication
Date de publication:
11 2022
11 2022
Historique:
received:
16
06
2022
revised:
10
08
2022
accepted:
23
08
2022
medline:
5
5
2023
pubmed:
28
8
2022
entrez:
27
8
2022
Statut:
ppublish
Résumé
Magnetic resonance elastography (MRE) is a phase contrast MRI technique which uses external palpation to create maps of brain mechanical properties noninvasively and in vivo. These mechanical properties are sensitive to tissue microstructure and reflect tissue integrity. MRE has been used extensively to study aging and neurodegeneration, and to assess individual cognitive differences in adults, but little is known about mechanical properties of the pediatric brain. Here we use high-resolution MRE imaging in participants of ages ranging from childhood to adulthood to understand brain mechanical properties across brain maturation. We find that brain mechanical properties differ considerably between childhood and adulthood, and that neuroanatomical subregions have differing maturational trajectories. Overall, we observe lower brain stiffness and greater brain damping ratio with increasing age from 5 to 35 years. Gray and white matter change differently during maturation, with larger changes occurring in gray matter for both stiffness and damping ratio. We also found that subregions of cortical and subcortical gray matter change differently, with the caudate and thalamus changing the most with age in both stiffness and damping ratio, while cortical subregions have different relationships with age, even between neighboring regions. Understanding how brain mechanical properties mature using high-resolution MRE will allow for a deeper understanding of the neural substrates supporting brain function at this age and can inform future studies of atypical maturation.
Identifiants
pubmed: 36030061
pii: S1053-8119(22)00705-4
doi: 10.1016/j.neuroimage.2022.119590
pmc: PMC9950297
mid: NIHMS1848521
pii:
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
119590Subventions
Organisme : NIMH NIH HHS
ID : R01 MH123470
Pays : United States
Organisme : NIBIB NIH HHS
ID : R01 EB027577
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103446
Pays : United States
Organisme : NINDS NIH HHS
ID : U01 NS112120
Pays : United States
Organisme : NIA NIH HHS
ID : R01 AG058853
Pays : United States
Organisme : NIGMS NIH HHS
ID : P20 GM103653
Pays : United States
Organisme : NICHD NIH HHS
ID : F31 HD103361
Pays : United States
Informations de copyright
Copyright © 2022 The Authors. Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflict of Interest There are no known conflicts of interest associated with this publication and there has been no significant financial support for this work that could have influenced its outcome.
Références
Prog Neurobiol. 2021 Sep;204:102109
pubmed: 34147583
J Cogn Neurosci. 2020 Sep;32(9):1704-1713
pubmed: 32379003
Phys Med Biol. 2016 Dec 21;61(24):R401-R437
pubmed: 27845941
Dev Cogn Neurosci. 2018 Nov;34:27-33
pubmed: 29906788
Eur Radiol. 2018 Aug;28(8):3347-3354
pubmed: 29460073
NMR Biomed. 2013 Nov;26(11):1534-9
pubmed: 23784982
Neuroimage. 2017 Jun;153:179-188
pubmed: 28366763
Neuroimage. 2016 Jan 15;125:144-152
pubmed: 26458518
Neuroimage. 2008 Apr 15;40(3):1044-55
pubmed: 18295509
Neuroimage Clin. 2013 Sep 20;3:381-7
pubmed: 24273721
Science. 2011 Sep 9;333(6048):1456-8
pubmed: 21778362
Dev Cogn Neurosci. 2020 Oct;45:100857
pubmed: 32927244
Neuroimage. 2015 May 1;111:59-64
pubmed: 25698157
IEEE Trans Med Imaging. 2013 Oct;32(10):1901-9
pubmed: 23797239
Hum Brain Mapp. 2016 Dec;37(12):4221-4233
pubmed: 27401228
PLoS One. 2011;6(9):e23451
pubmed: 21931599
Neuroradiology. 1997 Dec;39(12):841-6
pubmed: 9457706
Neuroimage. 2009 Jul 1;46(3):652-7
pubmed: 19281851
Phys Med Biol. 2022 Apr 15;67(9):
pubmed: 35316794
J Magn Reson Imaging. 2020 Mar;51(3):727-733
pubmed: 31373136
Philos Trans R Soc Lond B Biol Sci. 2018 Sep 24;373(1759):
pubmed: 30249772
Biomech Model Mechanobiol. 2019 Oct;18(5):1497-1505
pubmed: 31055692
Magn Reson Med. 2003 Jan;49(1):193-7
pubmed: 12509838
Neuroimage. 2009 Jun;46(2):530-41
pubmed: 19385018
Neuroimage. 2018 May 1;171:99-106
pubmed: 29317306
Neuroimage. 2020 Jul 15;215:116850
pubmed: 32298793
Eur Radiol. 2020 Dec;30(12):6614-6623
pubmed: 32683552
Magn Reson Med. 2022 Oct;88(4):1659-1672
pubmed: 35649188
Nat Rev Neurosci. 2003 Jan;4(1):37-48
pubmed: 12511860
IEEE Trans Med Imaging. 2001 Jan;20(1):45-57
pubmed: 11293691
PLoS One. 2013 Dec 02;8(12):e81668
pubmed: 24312570
J Magn Reson Imaging. 2011 Sep;34(3):494-8
pubmed: 21751286
Neuropsychol Rev. 2010 Dec;20(4):327-48
pubmed: 21042938
Neurobiol Aging. 2018 May;65:158-167
pubmed: 29494862
Proc Natl Acad Sci U S A. 2004 May 25;101(21):8174-9
pubmed: 15148381
Cereb Cortex. 2021 May 10;31(6):2799-2811
pubmed: 33454745
Nat Neurosci. 1999 Oct;2(10):861-3
pubmed: 10491603
Magn Reson Med. 2022 Aug;88(2):916-929
pubmed: 35381121
J Cogn Neurosci. 2019 Dec;31(12):1857-1872
pubmed: 31393232
Magn Reson Med. 2004 Dec;52(6):1388-96
pubmed: 15562493
Front Cell Neurosci. 2015 Jul 08;9:257
pubmed: 26217183
Cereb Cortex. 2012 Jan;22(1):1-12
pubmed: 21613470
Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6650-5
pubmed: 22492966
Magn Reson Med. 2014 Feb;71(2):477-85
pubmed: 24347237
Med Phys. 2012 Oct;39(10):6388-96
pubmed: 23039674
Neuroimage. 1999 Feb;9(2):179-94
pubmed: 9931268
J Mech Behav Biomed Mater. 2021 Mar;115:104229
pubmed: 33387852
Phys Med Biol. 2018 Jul 19;63(14):145021
pubmed: 29877194
J Child Neurol. 2020 Jun;35(7):463-471
pubmed: 32202191
Biol Sex Differ. 2012 Aug 21;3(1):19
pubmed: 22908911
Med Biol Eng Comput. 2008 Aug;46(8):759-66
pubmed: 18521645
Neurosci Biobehav Rev. 2006;30(6):718-29
pubmed: 16887188
J Pediatr. 2003 Oct;143(4 Suppl):S35-45
pubmed: 14597912
Neurobiol Aging. 2009 Oct;30(10):1657-76
pubmed: 18276037
Neuroimage Clin. 2015 Dec 19;10:283-90
pubmed: 26900568
Neuroimage. 2002 Oct;17(2):825-41
pubmed: 12377157
Dev Neuropsychol. 2022 Aug;47(5):258-272
pubmed: 35938379
NMR Biomed. 2019 Apr;32(4):e3778
pubmed: 28886240
Acta Biomater. 2019 Nov;99:433-442
pubmed: 31449927
Neuroimage. 2021 May 15;232:117889
pubmed: 33617995
Dev Neurosci. 2014;36(3-4):147-60
pubmed: 24993606
Brain Imaging Behav. 2020 Feb;14(1):175-185
pubmed: 30382528
Med Image Anal. 2001 Dec;5(4):237-54
pubmed: 11731304
Neuroimage. 2010 Feb 1;49(3):2520-5
pubmed: 19539039
Magn Reson Med. 2001 Oct;46(4):638-51
pubmed: 11590639
Nat Rev Neurosci. 2012 Dec;13(12):867-78
pubmed: 23165263
Brain Commun. 2020;2(1):fcz049
pubmed: 31998866
Dev Cogn Neurosci. 2018 Oct;33:54-72
pubmed: 29395939
Dev Cogn Neurosci. 2014 Jul;9:172-90
pubmed: 24879112
Neuropsychopharmacology. 2022 Jan;47(1):41-57
pubmed: 34645980
Trends Cogn Sci. 2005 Feb;9(2):60-8
pubmed: 15668098
Neuroimage. 2012 Mar;60(1):340-52
pubmed: 22178809
Dev Cogn Neurosci. 2018 Oct;33:176-181
pubmed: 29239832
Neuroimage. 2016 May 15;132:534-541
pubmed: 26931816
IEEE Trans Med Imaging. 2003 Feb;22(2):178-88
pubmed: 12715994
PLoS One. 2012;7(1):e29888
pubmed: 22276134
Biol Psychiatry. 2020 Jul 1;88(1):63-69
pubmed: 32245576