Urinary glyphosate kinetics after occupational exposure.
Elimination half-life
Glyphosate
Herbicide
Occupational exposure
Toxicokinetic
Urine
Journal
International journal of hygiene and environmental health
ISSN: 1618-131X
Titre abrégé: Int J Hyg Environ Health
Pays: Germany
ID NLM: 100898843
Informations de publication
Date de publication:
08 2022
08 2022
Historique:
received:
14
02
2022
revised:
12
07
2022
accepted:
03
08
2022
pubmed:
19
8
2022
medline:
14
9
2022
entrez:
18
8
2022
Statut:
ppublish
Résumé
Glyphosate-surfactant herbicides are the most used and imported herbicide in Thailand. Urinary biomonitoring is a very important tool for evaluating glyphosate exposures and its adverse health effects. However, the data for glyphosate toxicokinetics, especially in Asian populations, is relatively limited. The majority of farmers in Thailand have long term experience with glyphosate use, but they generally follow poor safety practices, including insufficient or incorrect use of personal protective equipment during pesticide handling activities. Therefore, this study aimed to determine the toxicokinetics of glyphosate and its metabolite in urine among maize farmers from the northern region of Thailand. The effects of personal protective equipment usage, as well as farmer behavior during work, on urinary glyphosate levels were also studied. Full-voided spot urine samples were collected over the exposure assessment period (0-72 h). Urinary glyphosate levels were determined by liquid chromatography tandem mass spectrometry. The maximum concentration in urine (uC
Identifiants
pubmed: 35981405
pii: S1438-4639(22)00104-3
doi: 10.1016/j.ijheh.2022.114021
pii:
doi:
Substances chimiques
Herbicides
0
Glycine
TE7660XO1C
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
114021Informations de copyright
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