Cultivating Clinical Clarity through Computer Vision: A Current Perspective on Whole Slide Imaging and Artificial Intelligence.

artificial intelligence (AI) computer vision deep learning diagnostics digital pathology digital workflow informatics laboratory medicine machine learning whole slide imaging (WSI)

Journal

Diagnostics (Basel, Switzerland)
ISSN: 2075-4418
Titre abrégé: Diagnostics (Basel)
Pays: Switzerland
ID NLM: 101658402

Informations de publication

Date de publication:
22 Jul 2022
Historique:
received: 19 06 2022
revised: 10 07 2022
accepted: 11 07 2022
entrez: 27 7 2022
pubmed: 28 7 2022
medline: 28 7 2022
Statut: epublish

Résumé

Diagnostic devices, methodological approaches, and traditional constructs of clinical pathology practice, cultivated throughout centuries, have transformed radically in the wake of explosive technological growth and other, e.g., environmental, catalysts of change. Ushered into the fray of modern laboratory medicine are digital imaging devices and machine-learning (ML) software fashioned to mitigate challenges, e.g., practitioner shortage while preparing clinicians for emerging interconnectivity of environments and diagnostic information in the era of big data. As computer vision shapes new constructs for the modern world and intertwines with clinical medicine, cultivating clarity of our new terrain through examining the trajectory and current scope of computational pathology and its pertinence to clinical practice is vital. Through review of numerous studies, we find developmental efforts for ML migrating from research to standardized clinical frameworks while overcoming obstacles that have formerly curtailed adoption of these tools, e.g., generalizability, data availability, and user-friendly accessibility. Groundbreaking validatory efforts have facilitated the clinical deployment of ML tools demonstrating the capacity to effectively aid in distinguishing tumor subtype and grade, classify early vs. advanced cancer stages, and assist in quality control and primary diagnosis applications. Case studies have demonstrated the benefits of streamlined, digitized workflows for practitioners alleviated by decreased burdens.

Identifiants

pubmed: 35892487
pii: diagnostics12081778
doi: 10.3390/diagnostics12081778
pmc: PMC9332710
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

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Auteurs

Ankush U Patel (AU)

Mayo Clinic Department of Laboratory Medicine and Pathology, Rochester, MN 55905, USA.

Nada Shaker (N)

Department of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA.

Sambit Mohanty (S)

CORE Diagnostics, Gurugram 122016, India.
Advanced Medical Research Institute, Bareilly 243001, India.

Shivani Sharma (S)

CORE Diagnostics, Gurugram 122016, India.

Shivam Gangal (S)

Department of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA.
College of Engineering, Biomedical Engineering, The Ohio State University, Columbus, OH 43210, USA.

Catarina Eloy (C)

Institute of Molecular Pathology and Immunology of the University of Porto (IPATIMUP), Rua Júlio Amaral de Carvalho, 45, 4200-135 Porto, Portugal.
Institute for Research and Innovation in Health (I3S Consortium), Rua Alfredo Allen, 208, 4200-135 Porto, Portugal.

Anil V Parwani (AV)

Department of Pathology, Wexner Medical Center, The Ohio State University, Columbus, OH 43210, USA.
Cooperative Human Tissue Network (CHTN) Midwestern Division, Columbus, OH 43240, USA.

Classifications MeSH