An overview of radiation-induced heart disease.
Antioxidants
Cardiomyopathies
Coronary artery disease
Inflammation
Oxidative stress
Radiation-induced abnormalities
Radiotherapy
Journal
Radiation oncology journal
ISSN: 2234-1900
Titre abrégé: Radiat Oncol J
Pays: Korea (South)
ID NLM: 101577577
Informations de publication
Date de publication:
Jun 2022
Jun 2022
Historique:
received:
10
08
2021
accepted:
20
05
2022
entrez:
7
7
2022
pubmed:
8
7
2022
medline:
8
7
2022
Statut:
ppublish
Résumé
Radiation therapy (RT) has dramatically improved cancer survival, leading to several inevitable complications. Unintentional irradiation of the heart can lead to radiation-induced heart disease (RIHD), including cardiomyopathy, pericarditis, coronary artery disease, valvular heart disease, and conduction system abnormalities. Furthermore, the development of RIHD is aggravated with the addition of chemotherapy. The screening, diagnosis, and follow-up for RIHD in patients who have undergone RT are described by the consensus guidelines from the European Association of Cardiovascular Imaging (EACVI) and the American Society of Echocardiography (ASE). There is compelling evidence that chest RT can increase the risk of heart disease. Although the prevalence and severity of RIHD are likely to be reduced with modern RT techniques, the incidence of RIHD is expected to rise in cancer survivors who have been treated with old RT regimens. However, there remains a gap between guidelines and clinical practice. Currently, therapeutic modalities followed in the treatment of RIHD are similar to the non-irradiated population. Preventive measures mainly reduce the radiation dose and radiation volume of the heart. There is no concrete evidence to endorse the preventive role of statins, angiotensin-converting enzyme inhibitors, and antioxidants. This review summarizes the current evidence of RIHD subtypes and risk factors and suggests screening regimens, diagnosis, treatment, and preventive approaches.
Identifiants
pubmed: 35796112
pii: roj.2021.00766
doi: 10.3857/roj.2021.00766
pmc: PMC9262704
doi:
Types de publication
Journal Article
Langues
eng
Pagination
89-102Références
Int J Radiat Oncol Biol Phys. 2021 Jun 1;110(2):473-481
pubmed: 33421556
Int J Radiat Oncol Biol Phys. 2016 Jul 1;95(3):1075-1082
pubmed: 27130788
Chemotherapy. 2020;65(3-4):65-76
pubmed: 33049738
Radiat Oncol. 2015 Jul 10;10:141
pubmed: 26159409
Am J Cardiol. 2021 Mar 15;143:14-20
pubmed: 33359199
J Am Heart Assoc. 2020 Sep 15;9(18):e018403
pubmed: 32893704
JAMA Oncol. 2021 Feb 01;7(2):206-219
pubmed: 33331883
Am J Cardiol. 2018 Nov 1;122(9):1578-1587
pubmed: 30220416
J Clin Oncol. 2018 Aug 1;36(22):2288-2296
pubmed: 29791285
Blood. 2017 Apr 20;129(16):2257-2265
pubmed: 28143884
Radiat Oncol. 2019 Feb 7;14(1):29
pubmed: 30732640
JAMA. 1993 Oct 27;270(16):1949-55
pubmed: 8411552
Clin Res Cardiol. 2021 Apr;110(4):507-531
pubmed: 33591377
Cleve Clin J Med. 2016 Dec;83(12):914-922
pubmed: 27938516
Cardiooncology. 2020 Jul 14;6:8
pubmed: 32685198
Medicina (Kaunas). 2019 May 09;55(5):
pubmed: 31075882
Breast Cancer Res Treat. 2017 Nov;166(1):249-257
pubmed: 28717853
Jpn J Med. 1990 Jan-Feb;29(1):104-10
pubmed: 2214340
Radiat Res. 2016 Nov;186(5):478-488
pubmed: 27841740
Breast. 2016 Feb;25:45-50
pubmed: 26547836
Am Heart J. 1992 Dec;124(6):1598-602
pubmed: 1462919
Int J Radiat Oncol Biol Phys. 2010 Mar 1;76(3 Suppl):S77-85
pubmed: 20171522
PLoS One. 2015 Sep 02;10(9):e0137337
pubmed: 26332771
Can J Physiol Pharmacol. 2017 Oct;95(10):1190-1203
pubmed: 28750189
Radiother Oncol. 2015 Jan;114(1):96-103
pubmed: 25465731
Aging (Albany NY). 2020 Aug 15;12(15):15741-15755
pubmed: 32805729
Front Cardiovasc Med. 2017 Oct 26;4:66
pubmed: 29124057
Int J Radiat Oncol Biol Phys. 2004 Mar 15;58(4):1228-34
pubmed: 15001267
Pract Radiat Oncol. 2022 Sep-Oct;12(5):e368-e375
pubmed: 35151923
Am Heart J. 2005 Nov;150(5):977-82
pubmed: 16290974
Radiat Res. 2015 Dec;184(6):611-20
pubmed: 26579943
Circulation. 2013 Apr 9;127(14):1476-85
pubmed: 23569119
Med Hypotheses. 2018 Feb;111:58-60
pubmed: 29406998
Radiother Oncol. 2009 Sep;92(3):492-9
pubmed: 19615773
Circ Heart Fail. 2016 Jan;9(1):e002661
pubmed: 26747861
Radiat Oncol. 2017 Jul 17;12(1):120
pubmed: 28716107
Blood. 2011 Jan 13;117(2):412-8
pubmed: 20858859
Int J Radiat Oncol Biol Phys. 2016 Apr 1;94(5):1061-72
pubmed: 27026313
Curr Treat Options Cardiovasc Med. 2014 Jun;16(6):317
pubmed: 24756471
J Clin Oncol. 2007 Jan 1;25(1):43-9
pubmed: 17194904
Eur Heart J Cardiovasc Imaging. 2013 Aug;14(8):721-40
pubmed: 23847385
Eur Heart J. 2016 Sep 21;37(36):2768-2801
pubmed: 27567406
J Am Heart Assoc. 2017 May 5;6(5):
pubmed: 28476874
Circulation. 2017 Apr 11;135(15):1388-1396
pubmed: 28132957
Heart. 2016 Feb 15;102(4):269-76
pubmed: 26661320
Int J Radiat Oncol Biol Phys. 2016 Mar 15;94(4):700-8
pubmed: 26972642
Eur Heart J. 2014 Mar;35(10):612-23
pubmed: 23666251
J Thorac Oncol. 2014 Oct;9(10):1554-60
pubmed: 25521400
Int J Radiat Oncol Biol Phys. 2017 Sep 1;99(1):51-60
pubmed: 28816160
Radiother Oncol. 2011 Nov;101(2):316-21
pubmed: 21925755
JAMA Intern Med. 2015 Jun;175(6):1007-17
pubmed: 25915855
Eur J Pharmacol. 2012 Oct 5;692(1-3):46-51
pubmed: 22771294
J Am Coll Cardiol. 2013 Jun 11;61(23):2319-28
pubmed: 23583253
Int J Radiat Oncol Biol Phys. 2021 Nov 15;111(4):907-916
pubmed: 34302893
J Am Coll Cardiol. 2019 Jun 18;73(23):2976-2987
pubmed: 31196455
JAMA Oncol. 2021 Jul 01;7(7):1024-1032
pubmed: 33956083
Curr Atheroscler Rep. 2019 Nov 19;21(12):50
pubmed: 31741087
Radiat Oncol. 2013 Sep 23;8:221
pubmed: 24053357
Circulation. 2006 Dec 12;114(24):2655-62
pubmed: 17116771
Cardiol Res Pract. 2011 Feb 27;2011:317659
pubmed: 21403872
Pract Radiat Oncol. 2021 Sep-Oct;11(5):e459-e467
pubmed: 33476841
Acta Oncol. 2020 Oct;59(10):1193-1200
pubmed: 32678696
Int J Radiat Oncol Biol Phys. 2007 Jan 1;67(1):10-8
pubmed: 17189062
Breast. 2019 Feb;43:48-54
pubmed: 30447482
Eur Heart J. 2021 Sep 21;42(36):3599-3726
pubmed: 34447992
Int J Cardiol. 2017 Sep 15;243:204-208
pubmed: 28587740
Pract Radiat Oncol. 2017 Nov - Dec;7(6):e525-e529
pubmed: 28669706
J Natl Cancer Inst. 2015 Feb 23;107(4):
pubmed: 25713164
Hum Pathol. 1996 Aug;27(8):766-73
pubmed: 8760008
J Clin Med. 2021 Dec 28;11(1):
pubmed: 35011887
J Clin Oncol. 2017 Apr 10;35(11):1171-1178
pubmed: 28095159
Br J Cancer. 2009 Aug 18;101(4):575-81
pubmed: 19623176
Radiother Oncol. 2011 Aug;100(2):167-75
pubmed: 21752480
Front Oncol. 2015 Feb 18;5:39
pubmed: 25741474
Int J Radiat Oncol Biol Phys. 2021 Apr 1;109(5):1301-1310
pubmed: 33340602
J Am Heart Assoc. 2021 Sep 21;10(18):e021686
pubmed: 34482706
Rev Cardiovasc Med. 2014;15(3):232-44
pubmed: 25290729
Acta Oncol. 2003;42(1):4-9
pubmed: 12665324
Int J Radiat Oncol Biol Phys. 1992;22(5):887-96
pubmed: 1555981
Semin Radiat Oncol. 2010 Jul;20(3):201-7
pubmed: 20685583
Int J Cardiol. 2014 May 15;173(3):e40-1
pubmed: 24698259
Int J Biol Sci. 2019 Aug 8;15(10):2128-2138
pubmed: 31592122
Medicine (Baltimore). 2020 Sep 18;99(38):e21964
pubmed: 32957314
Med Phys. 2020 Feb;47(2):576-586
pubmed: 31794054
Int J Radiat Oncol Biol Phys. 2021 Aug 1;110(5):1350-1359
pubmed: 33713741
J Am Coll Cardiol. 2013 Jul 23;62(4):263-71
pubmed: 23684677
Front Oncol. 2014 Nov 14;4:327
pubmed: 25452938
Int J Radiat Oncol Biol Phys. 2008 Sep 1;72(1):170-7
pubmed: 18632215
J Natl Cancer Inst. 2007 Mar 7;99(5):365-75
pubmed: 17341728
Bratisl Lek Listy. 2018;119(1):54-59
pubmed: 29405732
Heart. 2016 Jul 1;102(13):1044-51
pubmed: 26908098
N Engl J Med. 2013 Mar 14;368(11):987-98
pubmed: 23484825
Radiother Oncol. 2020 Nov;152:126-132
pubmed: 33058951