Ethanol withdrawal-induced adaptations in prefrontal corticotropin releasing factor receptor 1-expressing neurons regulate anxiety and conditioned rewarding effects of ethanol.


Journal

Molecular psychiatry
ISSN: 1476-5578
Titre abrégé: Mol Psychiatry
Pays: England
ID NLM: 9607835

Informations de publication

Date de publication:
08 2022
Historique:
received: 21 08 2021
accepted: 23 05 2022
revised: 22 04 2022
pubmed: 7 6 2022
medline: 2 12 2022
entrez: 6 6 2022
Statut: ppublish

Résumé

Prefrontal circuits are thought to underlie aberrant emotion contributing to relapse in abstinence; however, the discrete cell-types and mechanisms remain largely unknown. Corticotropin-releasing factor and its cognate type-1 receptor, a prominent brain stress system, is implicated in anxiety and alcohol use disorder (AUD). Here, we tested the hypothesis that medial prefrontal cortex CRF1-expressing (mPFC

Identifiants

pubmed: 35668157
doi: 10.1038/s41380-022-01642-3
pii: 10.1038/s41380-022-01642-3
pmc: PMC9708587
doi:

Substances chimiques

Receptors, Corticotropin-Releasing Hormone 0
Ethanol 3K9958V90M
Corticotropin-Releasing Hormone 9015-71-8

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3441-3451

Subventions

Organisme : NIAAA NIH HHS
ID : R01 AA027700
Pays : United States
Organisme : NIAAA NIH HHS
ID : U01 AA013498
Pays : United States
Organisme : NIAAA NIH HHS
ID : F32 AA026765
Pays : United States
Organisme : NIAAA NIH HHS
ID : R01 AA029841
Pays : United States
Organisme : NIAAA NIH HHS
ID : R37 AA017447
Pays : United States
Organisme : NIAAA NIH HHS
ID : T32 AA007456
Pays : United States
Organisme : NIAAA NIH HHS
ID : P60 AA006420
Pays : United States
Organisme : NIAAA NIH HHS
ID : R01 AA015566
Pays : United States
Organisme : NIAAA NIH HHS
ID : R01 AA021491
Pays : United States
Organisme : NIAAA NIH HHS
ID : U01 AA020926
Pays : United States
Organisme : NIAAA NIH HHS
ID : R01 AA012404
Pays : United States

Informations de copyright

© 2022. The Author(s).

Références

Neuropsychopharmacology. 2015 Aug;40(9):2066-75
pubmed: 25759300
Front Neuroendocrinol. 2014 Aug;35(3):320-30
pubmed: 24887405
Alcohol Clin Exp Res. 2016 Aug;40(8):1641-50
pubmed: 27374820
J Neurosci. 2016 Oct 19;36(42):10729-10741
pubmed: 27798128
Neuroendocrinology. 1983;36(3):165-86
pubmed: 6601247
Alcohol. 2019 May;76:37-45
pubmed: 30554034
Neurobiol Dis. 2011 Jun;42(3):300-10
pubmed: 21296667
Trends Pharmacol Sci. 2016 Dec;37(12):1045-1054
pubmed: 27717506
Front Neuroanat. 2017 Oct 10;11:90
pubmed: 29066956
Cell. 2016 Sep 22;167(1):60-72.e11
pubmed: 27641503
Brain Behav Immun. 2019 Jan;75:208-219
pubmed: 30791967
Alcohol Clin Exp Res. 1997 May;21(3):521-9
pubmed: 9161613
Brain Res. 2007 Dec;1186:212-23
pubmed: 18001698
Neuropharmacology. 2015 Dec;99:735-49
pubmed: 26188147
Proc Natl Acad Sci U S A. 2012 Oct 30;109(44):18156-61
pubmed: 23071333
eNeuro. 2020 Mar 5;7(2):
pubmed: 32041742
J Neurosci. 2013 Feb 20;33(8):3284-98
pubmed: 23426657
J Neurosci Res. 2017 Jan 2;95(1-2):518-526
pubmed: 27870449
Neuropsychopharmacology. 2016 Nov;41(12):2795-2797
pubmed: 27312404
Cereb Cortex. 2011 Jan;21(1):68-80
pubmed: 20392811
J Comp Neurol. 2008 Dec 1;511(4):479-96
pubmed: 18853426
Addict Behav. 2018 Feb;77:102-106
pubmed: 28992574
Blood. 2012 Feb 23;119(8):1810-20
pubmed: 22186992
Trends Neurosci. 2016 Jun;39(6):378-393
pubmed: 27083478
Psychopharmacology (Berl). 2015 Aug;232(16):2889-902
pubmed: 25899790
Ann Neurol. 1989 Sep;26(3):395-7
pubmed: 2529812
Neuropharmacology. 2018 May 1;133:470-480
pubmed: 29471053
Genome Biol. 2014;15(12):550
pubmed: 25516281
Neuropharmacology. 2017 Aug 1;122:136-147
pubmed: 28159647
Behav Brain Res. 2013 Jan 1;236(1):270-282
pubmed: 22985845
J Immunother Cancer. 2017 Jul 18;5(1):53
pubmed: 28716061
Alcohol. 2009 Feb;43(1):25-33
pubmed: 19185207
eNeuro. 2019 Jun 18;6(3):
pubmed: 31167849
J Physiol. 2008 Apr 15;586(8):2157-70
pubmed: 18308824
J Neurophysiol. 2015 Dec;114(6):3339-50
pubmed: 26445872
Neuropsychopharmacology. 2010 Jan;35(1):217-38
pubmed: 19710631
Cereb Cortex. 2006 Oct;16(10):1440-52
pubmed: 16339088
Biol Psychiatry. 2016 Nov 15;80(10):743-753
pubmed: 27318500
Biol Psychiatry. 2018 Jan 1;83(1):38-49
pubmed: 28697890
J Neurosci. 1985 Dec;5(12):3189-203
pubmed: 3001239
Nat Rev Neurosci. 2011 Oct 20;12(11):652-69
pubmed: 22011681
Science. 2011 Sep 30;333(6051):1903-7
pubmed: 21885734
Nature. 2018 May;557(7705):375-380
pubmed: 29743677
Horm Behav. 2014 Jul;66(2):247-56
pubmed: 24848364
J Affect Disord. 2018 Aug 1;235:96-104
pubmed: 29655081
Neuroscience. 2011 Jan 26;173:82-92
pubmed: 21093544
Biol Psychiatry. 2008 May 1;63(9):832-9
pubmed: 18061145
J Neurosci. 2010 Dec 15;30(50):16970-82
pubmed: 21159967
J Neurosci. 1995 Oct;15(10):6340-50
pubmed: 7472399
Prog Neurobiol. 2021 Apr;199:101952
pubmed: 33197496
Neuron. 2020 Apr 22;106(2):301-315.e7
pubmed: 32101698
Psychol Addict Behav. 2019 Feb;33(1):58-68
pubmed: 30667237
PLoS One. 2012;7(5):e37541
pubmed: 22666364
Neuron. 2020 Mar 18;105(6):1062-1076.e6
pubmed: 31948734
Neuropsychopharmacology. 2016 Oct;41(11):2733-40
pubmed: 27272767
Biol Psychiatry. 2020 Dec 15;88(12):910-921
pubmed: 32680583
Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13123-8
pubmed: 20615973
Alcohol Clin Exp Res. 1991 Jun;15(3):418-27
pubmed: 1877728
Biol Psychiatry. 2010 May 1;67(9):831-9
pubmed: 20060104
J Comp Neurol. 2000 Dec 11;428(2):191-212
pubmed: 11064361
Biol Psychiatry. 2017 Oct 1;82(7):500-510
pubmed: 28209423
Behav Neurosci. 2005 Apr;119(2):420-8
pubmed: 15839788
Int Rev Neurobiol. 2017;136:5-51
pubmed: 29056155
Front Neuroendocrinol. 2014 Apr;35(2):171-9
pubmed: 24145148
Psychoneuroendocrinology. 2018 Apr;90:92-101
pubmed: 29477954
Neurosci Biobehav Rev. 2005;29(4-5):771-83
pubmed: 15890403
Alcohol Clin Exp Res. 2008 Jun;32(6):1001-13
pubmed: 18422840
Arch Neurol. 1988 Sep;45(9):990-2
pubmed: 3415529
Neuropharmacology. 2021 Mar 1;185:108438
pubmed: 33333103
J Neurosci. 2019 Mar 13;39(11):2080-2090
pubmed: 30651328
Neuroscience. 2016 May 3;321:197-209
pubmed: 26204817
Neuroscience. 2012 Jun 1;211:28-38
pubmed: 22414923
Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8410-5
pubmed: 18541912
Front Neuroendocrinol. 1995 Oct;16(4):362-82
pubmed: 8557170
Exp Brain Res. 1998 Dec;123(3):334-40
pubmed: 9860272
Neuropharmacology. 2014 Jan;76 Pt B:370-82
pubmed: 23747571
Neuropharmacology. 2017 Oct;125:418-428
pubmed: 28807676
Alcohol. 2015 Aug;49(5):435-52
pubmed: 26074423
Mol Psychiatry. 2020 Nov;25(11):2742-2758
pubmed: 32086434

Auteurs

Reesha R Patel (RR)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Sarah A Wolfe (SA)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Vittoria Borgonetti (V)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.
Dipartimento di Neuroscienze, Psicologia, Area del Farmaco e Salute del Bambino, Università degli Studi di Firenze, 50139, Firenze (FI), Italy.

Pauravi J Gandhi (PJ)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Larry Rodriguez (L)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Angela E Snyder (AE)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Shannon D'Ambrosio (S)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Michal Bajo (M)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Alain Domissy (A)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Steven Head (S)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Candice Contet (C)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

R Dayne Mayfield (R)

Department of Neuroscience, The University of Texas at Austin, Austin, TX, 78712, USA.
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, TX, 78712, USA.

Amanda J Roberts (AJ)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA.

Marisa Roberto (M)

The Scripps Research Institute, 10550N. Torrey Pines Rd, La Jolla, CA, 92037, USA. mroberto@scripps.edu.

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Classifications MeSH