Bruins-in-Genomics: Evaluation of the impact of a UCLA undergraduate summer program in computational biology on participating students.


Journal

PloS one
ISSN: 1932-6203
Titre abrégé: PLoS One
Pays: United States
ID NLM: 101285081

Informations de publication

Date de publication:
2022
Historique:
received: 03 02 2022
accepted: 07 05 2022
entrez: 27 5 2022
pubmed: 28 5 2022
medline: 1 6 2022
Statut: epublish

Résumé

Recruiting, training and retaining scientists in computational biology is necessary to develop a workforce that can lead the quantitative biology revolution. Yet, African-American/Black, Hispanic/Latinx, Native Americans, and women are severely underrepresented in computational biosciences. We established the UCLA Bruins-in-Genomics Summer Research Program to provide training and research experiences in quantitative biology and bioinformatics to undergraduate students with an emphasis on students from backgrounds underrepresented in computational biology. Program assessment was based on number of applicants, alumni surveys and comparison of post-graduate educational choices for participants and a control group of students who were accepted but declined to participate. We hypothesized that participation in the Bruins-in-Genomics program would increase the likelihood that students would pursue post-graduate education in a related field. Our surveys revealed that 75% of Bruins-in-Genomics Summer participants were enrolled in graduate school. Logistic regression analysis revealed that women who participated in the program were significantly more likely to pursue a Ph.D. than a matched control group (group x woman interaction term of p = 0.005). The Bruins-in-Genomics Summer program represents an example of how a combined didactic-research program structure can make computational biology accessible to a wide range of undergraduates and increase participation in quantitative biosciences.

Identifiants

pubmed: 35622842
doi: 10.1371/journal.pone.0268861
pii: PONE-D-22-02856
pmc: PMC9140266
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0268861

Subventions

Organisme : NIMH NIH HHS
ID : R25 MH109172
Pays : United States
Organisme : NINDS NIH HHS
ID : R25 NS115554
Pays : United States

Déclaration de conflit d'intérêts

The authors have declared that no competing interests exist.

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Auteurs

Hilary A Coller (HA)

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, United States of America.
Department of Biological Chemistry, David Geffen School of Medicine, Los Angeles, CA, United States of America.
Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Molecular Biology Institute, University of California, Los Angeles, CA, United States of America.
Institute for Quantitative and Computational Biology, University of California, Los Angeles, CA, United States of America.

Stacey Beggs (S)

Department of Computational Medicine, David Geffen School of Medicine, Los Angeles, CA, United States of America.

Samantha Andrews (S)

Department of Computational Medicine, David Geffen School of Medicine, Los Angeles, CA, United States of America.

Jeff Maloy (J)

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, United States of America.

Alec Chiu (A)

Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.

Sriram Sankararaman (S)

Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Institute for Quantitative and Computational Biology, University of California, Los Angeles, CA, United States of America.
Department of Computational Medicine, David Geffen School of Medicine, Los Angeles, CA, United States of America.
Department of Computer Science, University of California, Los Angeles, CA, United States of America.

Matteo Pellegrini (M)

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, United States of America.
Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Molecular Biology Institute, University of California, Los Angeles, CA, United States of America.
Institute for Quantitative and Computational Biology, University of California, Los Angeles, CA, United States of America.

Nelson Freimer (N)

Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Molecular Biology Institute, University of California, Los Angeles, CA, United States of America.
Department of Genetics, David Geffen School of Medicine, Los Angeles, CA, United States of America.
Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine, Los Angeles, CA, United States of America.

Tracy Johnson (T)

Department of Molecular, Cell and Developmental Biology, University of California, Los Angeles, CA, United States of America.
Molecular Biology Institute, University of California, Los Angeles, CA, United States of America.

Jeanette Papp (J)

Department of Genetics, David Geffen School of Medicine, Los Angeles, CA, United States of America.

Eleazar Eskin (E)

Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Institute for Quantitative and Computational Biology, University of California, Los Angeles, CA, United States of America.
Department of Computational Medicine, David Geffen School of Medicine, Los Angeles, CA, United States of America.

Alexander Hoffmann (A)

Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA, United States of America.
Molecular Biology Institute, University of California, Los Angeles, CA, United States of America.
Institute for Quantitative and Computational Biology, University of California, Los Angeles, CA, United States of America.
Department of Microbiology, Immunology, and Molecular Genetics, Los Angeles, CA, United States of America.

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