Controversies in Systemic Lupus Erythematosus 2021: Changing the Paradigm in the Management of Lupus Nephritis.


Journal

Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases
ISSN: 1536-7355
Titre abrégé: J Clin Rheumatol
Pays: United States
ID NLM: 9518034

Informations de publication

Date de publication:
01 Jun 2022
Historique:
entrez: 26 5 2022
pubmed: 27 5 2022
medline: 31 5 2022
Statut: ppublish

Résumé

Lupus nephritis (LN) affects about a third of patients with systemic lupus erythematosus. Although the use of conventional therapy has significantly improved the prognosis of LN, the response to treatment remains suboptimal, with high rates of relapse and the occurrence of end-stage kidney disease. The implementation of new diagnostic and treatment strategies aimed at improving these outcomes represents a necessary paradigm shift in the management of LN.Herein, we discuss different points of view regarding these still unresolved issues; these comments represent a debate that took place during the virtual congress of the Pan American League of Associations for Rheumatology (PANLAR) and which was organized by the PANLAR Lupus Study Group, GLADEL (Grupo Latino Americano De Estudio del Lupus) on August 15, 2021.

Identifiants

pubmed: 35616510
doi: 10.1097/RHU.0000000000001859
pii: 00124743-202206000-00009
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

229-233

Informations de copyright

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Déclaration de conflit d'intérêts

S.V.P., A.E., M.G., B.A.P.-E., and G.S.A have no conflicts of interest to declare. R.F. has received consulting fees from GSK and Aurinia Pharmaceuticals. F.H. has received consultant fees from GSK, Astra-Zeneca, and Idorsia. B.H.R. has received consulting fees from GSK and Aurinia Pharmacetuicals. G.J.P.-E. is a speaker, is a consultant, and received grants from Pfizer, Janssen, GSK, Sandoz, and Sanofi.

Références

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Auteurs

Sabrina Valeria Porta (SV)

From the Rheumatology Department, Carlos G. Durand Hospital, Buenos Aires, Argentina.

Antoine Enfrein (A)

Internal Medicine Department, Centre Hospitalier Universitaire de Nantes, Nantes, France.

Mercedes García (M)

Rheumatology Department, Hospital Interzonal General de Agudos San Martin de La Plata, La Plata, Argentina.

Richard Furie (R)

Division of Rheumatology, Northwell Health, Great Neck, NY.

Brad H Rovin (BH)

Division of Nephrology, Ohio State University Wexner Medical Center, Columbus, OH.

Bernardo A Pons-Estel (BA)

Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Argentina.

Guillermo J Pons-Estel (GJ)

Centro Regional de Enfermedades Autoinmunes y Reumáticas (GO-CREAR), Rosario, Argentina.

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