Basal-Like Cell-Conditioned Medium Exerts Anti-Fibrotic Effects

PGE2 aberrant basaloid cells basal cells conditioned medium idiopathic pulmonary fibrosis lung fibroblasts

Journal

Frontiers in bioengineering and biotechnology
ISSN: 2296-4185
Titre abrégé: Front Bioeng Biotechnol
Pays: Switzerland
ID NLM: 101632513

Informations de publication

Date de publication:
2022
Historique:
received: 27 12 2021
accepted: 04 02 2022
entrez: 30 3 2022
pubmed: 31 3 2022
medline: 31 3 2022
Statut: epublish

Résumé

In idiopathic pulmonary fibrosis (IPF), basal-like cells are atypically present in the alveolar region, where they may affect adjacent stromal cells by paracrine mechanisms. We here aimed to confirm the presence of basal-like cells in peripheral IPF lung tissue

Identifiants

pubmed: 35350187
doi: 10.3389/fbioe.2022.844119
pii: 844119
pmc: PMC8957873
doi:

Types de publication

Journal Article

Langues

eng

Pagination

844119

Informations de copyright

Copyright © 2022 Khan, Fytianos, Blumer, Roux, Gazdhar, Savic, Knudsen, Jonigk, Kuehnel, Mykoniati, Tamm, Geiser and Hostettler.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Petra Khan (P)

Department of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.

Kleanthis Fytianos (K)

Department of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.

Sabrina Blumer (S)

Department of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.

Julien Roux (J)

Department of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.
Swiss Institute of Bioinformatics, Basel, Switzerland.

Amiq Gazdhar (A)

Department of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.

Spasenija Savic (S)

Institute of Medical Genetics and Pathology, University Hospital Basel, University of Basel, Basel, Switzerland.

Lars Knudsen (L)

Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany.
Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.

Danny Jonigk (D)

Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Institute of Pathology, Hannover Medical School, Hannover, Germany.

Mark P Kuehnel (MP)

Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany.
Institute of Pathology, Hannover Medical School, Hannover, Germany.

Sofia Mykoniati (S)

Department of Internal Medicine, Jura Cantonal Hospital, Delemont, Switzerland.

Michael Tamm (M)

Department of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.

Thomas Geiser (T)

Department of Pulmonary Medicine, University Hospital Bern, and Department of Biomedical Research, University of Bern, Bern, Switzerland.

Katrin E Hostettler (KE)

Department of Biomedicine and Clinics of Respiratory Medicine, University Hospital Basel, University of Basel, Basel, Switzerland.

Classifications MeSH