Response to botulinum neurotoxin injections in large-angle infantile esotropia: a post hoc analysis.
Journal
Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus
ISSN: 1528-3933
Titre abrégé: J AAPOS
Pays: United States
ID NLM: 9710011
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
received:
31
03
2021
revised:
03
11
2021
accepted:
07
11
2021
pubmed:
24
3
2022
medline:
12
5
2022
entrez:
23
3
2022
Statut:
ppublish
Résumé
To determine the anticipated reduction of baseline angle of esotropia and identify predictors of change following botulinum neurotoxin (BNT) injections in large-angle infantile esotropia. This was a prospective, longitudinal study of children <10 years of age diagnosed with infantile esotropia of >30 A total of 117 children were included, 55 in group 1 and 62 in group 2. Mean age was 30.3 ± 18.8 months. Mean baseline deviation was 62.5 In large-angle esotropia there was a reduction of approximately 50% of baseline deviation, with greater relative reduction for smaller baseline deviations; the absolute change in angle was greater in younger children. Alignment after subsequent surgery appeared to remain stable and surgery required less recession than would have been needed for the original angle of esotropia.
Identifiants
pubmed: 35318152
pii: S1091-8531(22)00058-1
doi: 10.1016/j.jaapos.2021.11.017
pii:
doi:
Substances chimiques
Neurotoxins
0
Botulinum Toxins
EC 3.4.24.69
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
79.e1-79.e5Informations de copyright
Copyright © 2022 American Association for Pediatric Ophthalmology and Strabismus. Published by Elsevier Inc. All rights reserved.