Association between hamstring coactivation during isokinetic quadriceps strength testing and knee cartilage worsening over 24 months.


Journal

Osteoarthritis and cartilage
ISSN: 1522-9653
Titre abrégé: Osteoarthritis Cartilage
Pays: England
ID NLM: 9305697

Informations de publication

Date de publication:
06 2022
Historique:
received: 07 06 2021
revised: 24 02 2022
accepted: 07 03 2022
pubmed: 22 3 2022
medline: 20 5 2022
entrez: 21 3 2022
Statut: ppublish

Résumé

This study aimed to determine longitudinal associations, including sex-specific differences, between greater knee flexor antagonist coactivation and worsening cartilage morphology in knees with or at risk for osteoarthritis (OA). Baseline measurements were collected at the 60-month visit of a longitudinal osteoarthritis study following community-dwelling participants (MOST). Knee flexor and extensor muscle activity were measured with surface electromyography during a maximal isokinetic knee extension task. MRI analyzed knee cartilage morphology at baseline and 24-month follow-up. Multivariable adjusted logistic regression models were used to assess associations between coactivation level and cartilage morphology worsening. Analysis of 373 women (mean ± SD age 67.4 ± 7.3 years and BMI 29.7 ± 5.0 kg/m These findings suggest a longitudinal relationship between antagonist hamstring coactivation during isokinetic knee extensor testing and worsening of cartilage morphology over 24 months in men with or at risk for knee OA.

Identifiants

pubmed: 35307535
pii: S1063-4584(22)00686-0
doi: 10.1016/j.joca.2022.03.002
pmc: PMC9450915
mid: NIHMS1831149
pii:
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

823-831

Subventions

Organisme : NIA NIH HHS
ID : U01 AG018947
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG018832
Pays : United States
Organisme : NIAMS NIH HHS
ID : P30 AR072571
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG019069
Pays : United States
Organisme : NIA NIH HHS
ID : U01 AG018820
Pays : United States

Informations de copyright

Copyright © 2022 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.

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Auteurs

M T Murphy (MT)

Department of Rehabilitation Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mailstop 1046, Kansas City, KS, 66160, USA. Electronic address: mmurphy11@kumc.edu.

N Wang (N)

Department of Biostatistics and Epidemiology, Boston University, Boston, MA, USA. Electronic address: nwang10@bu.edu.

D T Felson (DT)

Department of Epidemiology, Boston University, Boston, MA, USA. Electronic address: dfelson@bu.edu.

M C Nevitt (MC)

Department of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, CA, USA. Electronic address: michael.nevitt@ucsf.edu.

C E Lewis (CE)

Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA. Electronic address: celewis@uabmc.edu.

L Frey-Law (L)

Department of Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, USA. Electronic address: laura-freylaw@uiowa.edu.

A Guermazi (A)

Department of Radiology, Boston University, Boston, MA, USA. Electronic address: guermazi@bu.edu.

N A Segal (NA)

Department of Rehabilitation Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard, Mailstop 1046, Kansas City, KS, 66160, USA. Electronic address: nsegal@kumc.edu.

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