Characterizing Esophageal Motility in Neonatal Intensive Care Unit Patients Using High Resolution Manometry.
bronchopulmonary dysplasia
congenital diaphragmatic hernia
dysphagia
esophageal atresia
esophageal motility
infant
preterm
Journal
Frontiers in pediatrics
ISSN: 2296-2360
Titre abrégé: Front Pediatr
Pays: Switzerland
ID NLM: 101615492
Informations de publication
Date de publication:
2022
2022
Historique:
received:
31
10
2021
accepted:
18
01
2022
entrez:
3
3
2022
pubmed:
4
3
2022
medline:
4
3
2022
Statut:
epublish
Résumé
To characterize esophageal motility and esophago-gastric junction (EGJ) function during feeding in neonatal intensive care unit (NICU) patients. High resolution manometry with impedance (HRIM) was used to investigate esophageal motility and EGJ function in patients admitted to the NICU. Twenty-eight preterm born infants with bronchopulmonary dysplasia (BPD), 12 born with isolated congenital diaphragmatic hernia (iCDH), and 10 with esophageal atresia (EA) were included. Thirteen healthy infants were included as controls. Esophageal motility and EGJ function were analyzed using objective esophageal bolus transport parameters. Normal esophageal peristaltic wave patterns were observed in all investigated infants without EA. Nine of 10 patients with EA presented with abnormal esophageal motor wave patterns. A total of 224 nutritive swallows were analyzed (controls, We conclude that esophageal motility studies using pressure-impedance analysis are feasible in young infants. Bolus transport mechanisms following nutritive swallows appeared well-established in all investigated infants with the exception of those with EA. EGJ relaxation was also functional after deglutition and EGJ function as an anti-reflux barrier appeared well-developed in all investigated NICU groups.
Identifiants
pubmed: 35237539
doi: 10.3389/fped.2022.806072
pmc: PMC8882608
doi:
Types de publication
Journal Article
Langues
eng
Pagination
806072Informations de copyright
Copyright © 2022 Rayyan, Omari, Cossey, Allegaert and Rommel.
Déclaration de conflit d'intérêts
NR and TO hold a patent on AIMplot, the software used to analyze the pressure flow data. Swallow Gateway™ resource is provided and hosted by Flinders University. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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